| Literature DB >> 30065949 |
Lifeng Yu1, Liqiang Ren1, Zhoubo Li1, Shuai Leng1, Cynthia H McCollough1.
Abstract
Energy-resolved photon-counting-detector CT (PCD-CT) is promising for material decomposition with multiple contrast agents using two or more energy bins. However, corrections for nonidealities of PCDs are required, which are still active research topics. In addition, PCD-CT is also likely to have a very high cost due to the current lack of mass production capabilities. We proposed an alternative approach to perform multienergy CT (MECT), which is achieved by acquiring triple or quadruple x-ray beam measurements on a dual-source CT scanner. This strategy was based on a "twin-beam" design on a single-source scanner for dual-energy CT. Examples of beam filters and spectra for triple and quadruple x-ray beam were provided. Computer simulation studies were performed to evaluate the noise and accuracy of material decomposition for multiple contrast mixtures using both triple- and quadruple-beam configurations, compared with the performance on a PCD-CT platform. The results demonstrated that the image quality and dose efficiency of the triple-beam configuration in the proposed MECT technique were comparable to that in PCD-CT. The proposed technique can be readily implemented on a dual-source scanner, which may allow material decomposition of multiple contrast agents to be performed on clinical CT scanners with energy-integrating detectors.Entities:
Keywords: basis material decomposition; dual-energy CT; dual-source CT; multienergy CT
Year: 2018 PMID: 30065949 PMCID: PMC6056773 DOI: 10.1117/1.JMI.5.3.033502
Source DB: PubMed Journal: J Med Imaging (Bellingham) ISSN: 2329-4302