Literature DB >> 28753599

Probes &Drugs portal: an interactive, open data resource for chemical biology.

Ctibor Skuta1, Martin Popr1, Tomas Muller1, Jindrich Jindrich1,2, Michal Kahle1, David Sedlak1, Daniel Svozil1,3, Petr Bartunek1.   

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Year:  2017        PMID： 28753599     DOI： 10.1038/nmeth.4365

Source DB:  PubMed          Journal:  Nat Methods        ISSN： 1548-7091            Impact factor:   28.547


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  6 in total

1.  The art of the chemical probe.

Authors:  Stephen V Frye
Journal:  Nat Chem Biol       Date:  2010-03       Impact factor: 15.040

Review 2.  Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes.

Authors:  Stuart L Schreiber; Joanne D Kotz; Min Li; Jeffrey Aubé; Christopher P Austin; John C Reed; Hugh Rosen; E Lucile White; Larry A Sklar; Craig W Lindsley; Benjamin R Alexander; Joshua A Bittker; Paul A Clemons; Andrea de Souza; Michael A Foley; Michelle Palmer; Alykhan F Shamji; Mathias J Wawer; Owen McManus; Meng Wu; Beiyan Zou; Haibo Yu; Jennifer E Golden; Frank J Schoenen; Anton Simeonov; Ajit Jadhav; Michael R Jackson; Anthony B Pinkerton; Thomas D Y Chung; Patrick R Griffin; Benjamin F Cravatt; Peter S Hodder; William R Roush; Edward Roberts; Dong-Hoon Chung; Colleen B Jonsson; James W Noah; William E Severson; Subramaniam Ananthan; Bruce Edwards; Tudor I Oprea; P Jeffrey Conn; Corey R Hopkins; Michael R Wood; Shaun R Stauffer; Kyle A Emmitte
Journal:  Cell       Date:  2015-06-04       Impact factor: 41.582

3.  Target validation using chemical probes.

Authors:  Mark E Bunnage; Eugene L Piatnitski Chekler; Lyn H Jones
Journal:  Nat Chem Biol       Date:  2013-04       Impact factor: 15.040

Review 4.  Probing the probes: fitness factors for small molecule tools.

Authors:  Paul Workman; Ian Collins
Journal:  Chem Biol       Date:  2010-06-25

5.  The promise and peril of chemical probes.

Authors:  Cheryl H Arrowsmith; James E Audia; Christopher Austin; Jonathan Baell; Jonathan Bennett; Julian Blagg; Chas Bountra; Paul E Brennan; Peter J Brown; Mark E Bunnage; Carolyn Buser-Doepner; Robert M Campbell; Adrian J Carter; Philip Cohen; Robert A Copeland; Ben Cravatt; Jayme L Dahlin; Dashyant Dhanak; Aled M Edwards; Mathias Frederiksen; Stephen V Frye; Nathanael Gray; Charles E Grimshaw; David Hepworth; Trevor Howe; Kilian V M Huber; Jian Jin; Stefan Knapp; Joanne D Kotz; Ryan G Kruger; Derek Lowe; Mary M Mader; Brian Marsden; Anke Mueller-Fahrnow; Susanne Müller; Ronan C O'Hagan; John P Overington; Dafydd R Owen; Saul H Rosenberg; Bryan Roth; Brian Roth; Ruth Ross; Matthieu Schapira; Stuart L Schreiber; Brian Shoichet; Michael Sundström; Giulio Superti-Furga; Jack Taunton; Leticia Toledo-Sherman; Chris Walpole; Michael A Walters; Timothy M Willson; Paul Workman; Robert N Young; William J Zuercher
Journal:  Nat Chem Biol       Date:  2015-08       Impact factor: 15.040

6.  Parallel worlds of public and commercial bioactive chemistry data.

Authors:  Christopher A Lipinski; Nadia K Litterman; Christopher Southan; Antony J Williams; Alex M Clark; Sean Ekins
Journal:  J Med Chem       Date:  2014-12-04       Impact factor: 7.446
  6 in total
  12 in total

Review 1.  Chemical probes and drug leads from advances in synthetic planning and methodology.

Authors:  Christopher J Gerry; Stuart L Schreiber
Journal:  Nat Rev Drug Discov       Date:  2018-04-13       Impact factor: 84.694

Review 2.  Online informatics resources to facilitate cancer target and chemical probe discovery.

Authors:  Xuan Yang; Haian Fu; Andrey A Ivanov
Journal:  RSC Med Chem       Date:  2020-04-09

3.  ICBS 2017 in Shanghai-Illuminating Life with Chemical Innovation.

Authors:  Qi Zhang; Jingyu Zhang; Evripidis Gavathiotis
Journal:  ACS Chem Biol       Date:  2018-05-02       Impact factor: 5.100

4.  Revealing new therapeutic opportunities through drug target prediction: a class imbalance-tolerant machine learning approach.

Authors:  Siqi Liang; Haiyuan Yu
Journal:  Bioinformatics       Date:  2020-08-15       Impact factor: 6.937

Review 5.  Drug combination therapy for emerging viral diseases.

Authors:  Zeenat A Shyr; Yu-Shan Cheng; Donald C Lo; Wei Zheng
Journal:  Drug Discov Today       Date:  2021-05-21       Impact factor: 7.851

Review 6.  Collection of analog series-based scaffolds from public compound sources.

Authors:  Dilyana Dimova; Jürgen Bajorath
Journal:  Future Sci OA       Date:  2018-02-08

7.  Probing the chemical-biological relationship space with the Drug Target Explorer.

Authors:  Robert J Allaway; Salvatore La Rosa; Justin Guinney; Sara J C Gosline
Journal:  J Cheminform       Date:  2018-08-20       Impact factor: 5.514

8.  ABC-transporter upregulation mediates resistance to the CDK7 inhibitors THZ1 and ICEC0942.

Authors:  Georgina P Sava; Hailing Fan; Rosemary A Fisher; Sabrina Lusvarghi; Sunil Pancholi; Suresh V Ambudkar; Lesley-Ann Martin; R Charles Coombes; Lakjaya Buluwela; Simak Ali
Journal:  Oncogene       Date:  2019-09-17       Impact factor: 9.867

Review 9.  The SGC beyond structural genomics: redefining the role of 3D structures by coupling genomic stratification with fragment-based discovery.

Authors:  Anthony R Bradley; Aude Echalier; Michael Fairhead; Claire Strain-Damerell; Paul Brennan; Alex N Bullock; Nicola A Burgess-Brown; Elisabeth P Carpenter; Opher Gileadi; Brian D Marsden; Wen Hwa Lee; Wyatt Yue; Chas Bountra; Frank von Delft
Journal:  Essays Biochem       Date:  2017-11-08       Impact factor: 8.000

10.  DrugCentral 2018: an update.

Authors:  Oleg Ursu; Jayme Holmes; Cristian G Bologa; Jeremy J Yang; Stephen L Mathias; Vasileios Stathias; Dac-Trung Nguyen; Stephan Schürer; Tudor Oprea
Journal:  Nucleic Acids Res       Date:  2019-01-08       Impact factor: 16.971
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