Literature DB >> 27489519

Dose distribution verification for GYN brachytherapy using EBT Gafchromic film and TG-43 calculation.

Somayeh Gholami1, Hamid Reza Mirzaei2, Ali Jabbary Arfaee2, Ramin Jaberi3, Hassan Ali Nedaie3, Seied Rabi Mahdavi4, Eftekhar Rajab Bolookat2, Ali S Meigooni5.   

Abstract

AIM: Verification of dose distributions for gynecological (GYN) brachytherapy implants using EBT Gafchromic film.
BACKGROUND: One major challenge in brachytherapy is to verify the accuracy of dose distributions calculated by a treatment planning system.
MATERIALS AND METHODS: A new phantom was designed and fabricated using 90 slabs of 18 cm × 16 cm × 0.2 cm Perspex to accommodate a tandem and Ovoid assembly, which is normally used for GYN brachytherapy treatment. This phantom design allows the use of EBT Gafchromic films for dosimetric verification of GYN implants with a cobalt-60 HDR system or a LDR Cs-137 system. Gafchromic films were exposed using a plan that was designed to deliver 1.5 Gy of dose to 0.5 cm distance from the lateral surface of ovoids from a pair of ovoid assembly that was used for treatment vaginal cuff. For a quantitative analysis of the results for both LDR and HDR systems, the measured dose values at several points of interests were compared with the calculated data from a commercially available treatment planning system. This planning system was utilizing the TG-43 formalism and parameters for calculation of dose distributions around a brachytherapy implant.
RESULTS: The results of these investigations indicated that the differences between the calculated and measured data at different points were ranging from 2.4% to 3.8% for the LDR Cs-137 and HDR Co-60 systems, respectively.
CONCLUSION: The EBT Gafchromic films combined with the newly designed phantom could be utilized for verification of the dose distributions around different GYN implants treated with either LDR or HDR brachytherapy procedures.

Entities:  

Keywords:  Film dosimetry; GZP6 HDR system; QA brachytherapy phantom; Selectron LDR system; TG-43

Year:  2016        PMID: 27489519      PMCID: PMC4959939          DOI: 10.1016/j.rpor.2016.06.005

Source DB:  PubMed          Journal:  Rep Pract Oncol Radiother        ISSN: 1507-1367


  22 in total

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2.  Grid Block Design Based on Monte Carlo Simulated Dosimetry, the Linear Quadratic and Hug-Kellerer Radiobiological Models.

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