Literature DB >> 265588

Minimal length of the lactose operator sequence for the specific recognition by the lactose repressor.

C P Bahl, R Wu, J Stawinsky, S A Narang.   

Abstract

A number of specific duplex DNA sequences which correspond to varying lengths of the lactose operator region have been synthesized by a combination of chemical and enzymatic methods. Repressor binding studies on these synthetic duplex operator molecules show that all the nucleotides essential for full lactose operator-repressor interactions are included in a 17-nucleotide-long duplex DNA that constitutes the minimal recognition sequence for this DNA-protein interaction.

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Year:  1977        PMID： 265588      PMCID： PMC430549          DOI： 10.1073/pnas.74.3.966

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  23 in total

1.  The predicted secondary structure of the N-terminal sequence of the lac repressor and proposed models for its complexation to the lac operator.

Authors:  D J Patel
Journal:  Biochemistry       Date:  1975-03-11       Impact factor: 3.162

2.  On the statistical significance of primary structural features found in DNA-protein interaction sites.

Authors:  G Dykes; R Bambara; K Marians; R Wu
Journal:  Nucleic Acids Res       Date:  1975-03       Impact factor: 16.971

3.  Genetic regulation: the Lac control region.

Authors:  R C Dickson; J Abelson; W M Barnes; W S Reznikoff
Journal:  Science       Date:  1975-01-10       Impact factor: 47.728

4.  Synthetic lac operator DNA is functional in vivo.

Authors:  H L Heyneker; J Shine; H M Goodman; H W Boyer; J Rosenberg; R E Dickerson; S A Narang; K Itakura; S Lin; A D Riggs
Journal:  Nature       Date:  1976-10-28       Impact factor: 49.962

5.  A general method for inserting specific DNA sequences into cloning vehicles.

Authors:  C P Bahl; K J Marians; R Wu
Journal:  Gene       Date:  1976       Impact factor: 3.688

6.  The use of arylsulfonyltriazoles for the synthesis of oligonucleotides by the triester approach.

Authors:  N Katagiri; K Itakura; S A Narang
Journal:  J Am Chem Soc       Date:  1975-12-10       Impact factor: 15.419

7.  Chemical synthesis and sequence studies of deoxyribooligonucleotides which constitute the duplex sequence of the lactose operator of Escherichia coli.

Authors:  K Itakura; N Katagiri; S A Narang; C P Bahl; K J Marians; R Wu
Journal:  J Biol Chem       Date:  1975-06-25       Impact factor: 5.157

8.  A reliable mapping method for sequence determination of oligodeoxyribonucleotides by mobility shift analysis.

Authors:  C P Tu; E Jay; C P Bahl; R Wu
Journal:  Anal Biochem       Date:  1976-07       Impact factor: 3.365

9.  Structure of the lactose operator.

Authors:  K J Marians; J D Brooker
Journal:  Nature       Date:  1976-03-25       Impact factor: 49.962

10.  Cloned synthetic lac operator DNA is biologically active.

Authors:  K J Marians; R Wu; J Stawinski; T Hozumi; S A Narang
Journal:  Nature       Date:  1976-10-28       Impact factor: 49.962
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  28 in total

1.  Comparative study of papovavirus DNA: BKV(MM), BKV(WT) and SV40.

Authors:  R C Yang; R Wu
Journal:  Nucleic Acids Res       Date:  1979-10-10       Impact factor: 16.971

2.  Enhanced bacterial protein expression during auto-induction obtained by alteration of lac repressor dosage and medium composition.

Authors:  Paul G Blommel; Katie J Becker; Petar Duvnjak; Brian G Fox
Journal:  Biotechnol Prog       Date:  2007-05-17

3.  Multi-scale genetic dynamic modelling II: application to synthetic biology: an algorithmic Markov chain based approach.

Authors:  Markus Kirkilionis; Ulrich Janus; Luca Sbano
Journal:  Theory Biosci       Date:  2011-04-21       Impact factor: 1.919

4.  CyanoGate: A Modular Cloning Suite for Engineering Cyanobacteria Based on the Plant MoClo Syntax.

Authors:  Ravendran Vasudevan; Grant A R Gale; Alejandra A Schiavon; Anton Puzorjov; John Malin; Michael D Gillespie; Konstantinos Vavitsas; Valentin Zulkower; Baojun Wang; Christopher J Howe; David J Lea-Smith; Alistair J McCormick
Journal:  Plant Physiol       Date:  2019-02-28       Impact factor: 8.340

5.  How lac repressor recognizes lac operator.

Authors:  D V Goeddel; D G Yansura; M H Caruthers
Journal:  Proc Natl Acad Sci U S A       Date:  1978-08       Impact factor: 11.205

6.  Binding of lac repressor to the secondary lac operator in Escherichia coli.

Authors:  A Rambach; M Lebastard
Journal:  Mol Gen Genet       Date:  1978-10-30

7.  Studies on gene control regions X. The effect of specific adenine-thymine transversions on the lac repressor-lac operator interaction.

Authors:  H S Sista; R T Loder; M H Caruthers
Journal:  Nucleic Acids Res       Date:  1979-06-11       Impact factor: 16.971

8.  Studies on gene control regions. VI. The 5- methyl of thymine, a lac repressor recognition site.

Authors:  D V Goeddel; D G Yansura; M H Caruthers
Journal:  Nucleic Acids Res       Date:  1977-09       Impact factor: 16.971

9.  Synthesis of human insulin gene. Part I. Development of reversed-phase chromatography in the modified triester method. Its application in the rapid and efficient synthesis of eight deoxyribooligonucleotides fragments constituting human insulin A DNA.

Authors:  H M Hsiung; R Brousseau; J Michniewicz; S A Narang
Journal:  Nucleic Acids Res       Date:  1979-04       Impact factor: 16.971

10.  Site-specific modification of the lactose operator with acetylaminofluorene.

Authors:  G Stöhrer; J A Osband; G Alvarado-Urbina
Journal:  Nucleic Acids Res       Date:  1983-08-11       Impact factor: 16.971
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