Literature DB >> 2646717

Nucleotides in yeast tRNAPhe required for the specific recognition by its cognate synthetase.

J R Sampson1, A B DiRenzo, L S Behlen, O C Uhlenbeck.   

Abstract

An analysis of the aminoacylation kinetics of unmodified yeast tRNAPhe mutants revealed that five single-stranded nucleotides are important for its recognition by yeast phenylalanyl-tRNA synthetase, provided they were positioned correctly in a properly folded tRNA structure. When four other tRNAs were changed to have these five nucleotides, they became near-normal substrates for the enzyme.

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Year:  1989        PMID： 2646717     DOI： 10.1126/science.2646717

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  69 in total

1.  An engineered class I transfer RNA with a class II tertiary fold.

Authors:  T A Nissan; B Oliphant; J J Perona
Journal:  RNA       Date:  1999-03       Impact factor: 4.942

2.  Modulation of tRNAAla identity by inorganic pyrophosphatase.

Authors:  Alexey D Wolfson; Olke C Uhlenbeck
Journal:  Proc Natl Acad Sci U S A       Date:  2002-04-30       Impact factor: 11.205

3.  A one-step method for in vitro production of tRNA transcripts.

Authors:  Dragana Korencić; Dieter Söll; Alexandre Ambrogelly
Journal:  Nucleic Acids Res       Date:  2002-10-15       Impact factor: 16.971

4.  Enzymatic aminoacylation of an eight-base-pair microhelix with histidine.

Authors:  C Francklyn; P Schimmel
Journal:  Proc Natl Acad Sci U S A       Date:  1990-11       Impact factor: 11.205

Review 5.  The accuracy of aminoacylation--ensuring the fidelity of the genetic code.

Authors:  D Söll
Journal:  Experientia       Date:  1990-12-01

6.  An anticodon change switches the identity of E. coli tRNA(mMet) from methionine to threonine.

Authors:  L H Schulman; H Pelka
Journal:  Nucleic Acids Res       Date:  1990-01-25       Impact factor: 16.971

7.  Rapid determination of nucleotides that define tRNA(Gly) acceptor identity.

Authors:  W H McClain; K Foss; R A Jenkins; J Schneider
Journal:  Proc Natl Acad Sci U S A       Date:  1991-07-15       Impact factor: 11.205

8.  Anticodon-independent aminoacylation of an RNA minihelix with valine.

Authors:  M Frugier; C Florentz; R Giegé
Journal:  Proc Natl Acad Sci U S A       Date:  1992-05-01       Impact factor: 11.205

9.  Identity elements of human tRNA(Leu): structural requirements for converting human tRNA(Ser) into a leucine acceptor in vitro.

Authors:  K Breitschopf; T Achsel; K Busch; H J Gross
Journal:  Nucleic Acids Res       Date:  1995-09-25       Impact factor: 16.971

10.  Replacement of RNA hairpins by in vitro selected tetranucleotides.

Authors:  B Dichtl; T Pan; A B DiRenzo; O C Uhlenbeck
Journal:  Nucleic Acids Res       Date:  1993-02-11       Impact factor: 16.971
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