| Literature DB >> 26309755 |
Paul Béland1, Oleksiy Krupin2, Pierre Berini3.
Abstract
Experimentation demonstrates long-range surface plasmon polariton waveguides as a useful biosensor to selectively detect gram negative or gram positive bacteria in human urine having a low concentration of constituents. The biosensor can detect bacteria at concentrations of 10(5) CFU/ml, the internationally recommended threshold for diagnostic of urinary tract infection. Using a negative control urine solution of bacterial concentration 1000☓ higher than the targeted bacteria, we obtain a ratio of 5.4 for the positive to negative signals.Entities:
Keywords: (130.3120) Integrated optics devices; (170.0170) Medical optics and biotechnology; (170.7230) Urology; (230.7390) Waveguides, planar; (240.6680) Surface plasmons; (250.5403) Plasmonics; (280.1415) Biological sensing and sensors
Year: 2015 PMID: 26309755 PMCID: PMC4541519 DOI: 10.1364/BOE.6.002908
Source DB: PubMed Journal: Biomed Opt Express ISSN: 2156-7085 Impact factor: 3.732