Literature DB >> 26287299

Postoperative Hypoxemia Is Common and Persistent: A Prospective Blinded Observational Study.

Zhuo Sun1, Daniel I Sessler, Jarrod E Dalton, P J Devereaux, Aram Shahinyan, Amanda J Naylor, Matthew T Hutcherson, Patrick S Finnegan, Vikas Tandon, Saeed Darvish-Kazem, Shaan Chugh, Hussain Alzayer, Andrea Kurz.   

Abstract

BACKGROUND: The incidence, severity, and duration of postoperative oxygen desaturation in the general surgical population are poorly characterized. We therefore used continuous pulse oximetry to quantify arterial oxygen saturation (SpO2) in a cross-section of patients having noncardiac surgery.
METHODS: Oxygen saturation, blinded to clinicians, was recorded at 1-minute intervals in patients >45 years old for up to 48 hours after noncardiac surgery in 1250 patients from Cleveland Clinic Main Campus and 250 patients from the Juravinski Hospital. We determined (1) the cumulative minutes of raw minute-by-minute values below various hypoxemic thresholds; and (2) the contiguous duration of kernel-smoothed (sliding window) values below various hypoxemic thresholds. Finally, we compared our blinded continuous values with saturations recorded during routine nursing care.
RESULTS: Eight hundred thirty-three patients had sufficient data for analyses. Twenty-one percent had ≥10 min/h with raw SpO2 values <90% averaged over the entire recording duration; 8% averaged ≥20 min/h <90%; and 8% averaged ≥5 min/h <85%. Prolonged hypoxemic episodes were common, with 37% of patients having at least 1 (smoothed) SpO2 <90% for an hour or more; 11% experienced at least 1 episode lasting ≥6 hours; and 3% had saturations <80% for at least 30 minutes. Clinical hypoxemia, according to nursing records, measured only in Cleveland Clinic patients (n = 594), occurred in 5% of the monitored patients. The nurses missed 90% of smoothed hypoxemic episodes in which saturation was <90% for at least one hour.
CONCLUSIONS: Hypoxemia was common and prolonged in hospitalized patients recovering from noncardiac surgery. The SpO2 values recorded in medical records seriously underestimated the severity of postoperative hypoxemia.

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Year:  2015        PMID: 26287299      PMCID: PMC4825673          DOI: 10.1213/ANE.0000000000000836

Source DB:  PubMed          Journal:  Anesth Analg        ISSN: 0003-2999            Impact factor:   6.627


  29 in total

1.  Who bounces back? Physiologic and other predictors of intensive care unit readmission.

Authors:  A L Rosenberg; T P Hofer; R A Hayward; C Strachan; C M Watts
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2.  Relationship between nocturnal hypoxaemia, tachycardia and myocardial ischaemia after major abdominal surgery.

Authors:  I Gögenur; S Rosenberg-Adamsen; C Lie; M Carstensen; V Rasmussen; J Rosenberg
Journal:  Br J Anaesth       Date:  2004-07-09       Impact factor: 9.166

3.  A comparison of oxygen saturation data in inpatients with low oxygen saturation using automated continuous monitoring and intermittent manual data charting.

Authors:  Andreas H Taenzer; Joshua Pyke; Michael D Herrick; Thomas M Dodds; Susan P McGrath
Journal:  Anesth Analg       Date:  2014-02       Impact factor: 5.108

4.  Postoperative mental confusion--association with postoperative hypoxemia.

Authors:  J Rosenberg; H Kehlet
Journal:  Surgery       Date:  1993-07       Impact factor: 3.982

5.  Missed opportunities? An observational study of vital sign measurements.

Authors:  Chris H Van Leuvan; Imogen Mitchell
Journal:  Crit Care Resusc       Date:  2008-06       Impact factor: 2.159

6.  Pulse oximetry in the postoperative care of cardiac surgical patients. A randomized controlled trail.

Authors:  M I Bierman; K L Stein; J V Snyder
Journal:  Chest       Date:  1992-11       Impact factor: 9.410

7.  Continuous oximetry/capnometry monitoring reveals frequent desaturation and bradypnea during patient-controlled analgesia.

Authors:  Frank J Overdyk; Rickey Carter; Ray R Maddox; Jarred Callura; Amy E Herrin; Craig Henriquez
Journal:  Anesth Analg       Date:  2007-08       Impact factor: 5.108

8.  Intraoperative tissue oxygenation and postoperative outcomes after major non-cardiac surgery: an observational study.

Authors:  B B Abdelmalak; J P Cata; A Bonilla; J You; T Kopyeva; J D Vogel; S Campbell; D I Sessler
Journal:  Br J Anaesth       Date:  2012-11-21       Impact factor: 9.166

Review 9.  Respiratory and haemodynamic effects of acute postoperative pain management: evidence from published data.

Authors:  J N Cashman; S J Dolin
Journal:  Br J Anaesth       Date:  2004-05-28       Impact factor: 9.166

10.  Myocardial injury after noncardiac surgery: a large, international, prospective cohort study establishing diagnostic criteria, characteristics, predictors, and 30-day outcomes.

Authors:  Fernando Botto; Pablo Alonso-Coello; Matthew T V Chan; Juan Carlos Villar; Denis Xavier; Sadeesh Srinathan; Gordon Guyatt; Patricia Cruz; Michelle Graham; C Y Wang; Otavio Berwanger; Rupert M Pearse; Bruce M Biccard; Valsa Abraham; German Malaga; Graham S Hillis; Reitze N Rodseth; Deborah Cook; Carisi A Polanczyk; Wojciech Szczeklik; Daniel I Sessler; Tej Sheth; Gareth L Ackland; Martin Leuwer; Amit X Garg; Yannick Lemanach; Shirley Pettit; Diane Heels-Ansdell; Giovanna Luratibuse; Michael Walsh; Robert Sapsford; Holger J Schünemann; Andrea Kurz; Sabu Thomas; Marko Mrkobrada; Lehana Thabane; Hertzel Gerstein; Pilar Paniagua; Peter Nagele; Parminder Raina; Salim Yusuf; P J Devereaux; P J Devereaux; Daniel I Sessler; Michael Walsh; Gordon Guyatt; Matthew J McQueen; Mohit Bhandari; Deborah Cook; Jackie Bosch; Norman Buckley; Salim Yusuf; Clara K Chow; Graham S Hillis; Richard Halliwell; Stephen Li; Vincent W Lee; John Mooney; Carisi A Polanczyk; Mariana V Furtado; Otavio Berwanger; Erica Suzumura; Eliana Santucci; Katia Leite; Jose Amalth do Espirirto Santo; Cesar A P Jardim; Alexandre Biasi Cavalcanti; Helio Penna Guimaraes; Michael J Jacka; Michelle Graham; Finlay McAlister; Sean McMurtry; Derek Townsend; Neesh Pannu; Sean Bagshaw; Amal Bessissow; Mohit Bhandari; Emmanuelle Duceppe; John Eikelboom; Javier Ganame; James Hankinson; Stephen Hill; Sanjit Jolly; Andre Lamy; Elizabeth Ling; Patrick Magloire; Guillaume Pare; Deven Reddy; David Szalay; Jacques Tittley; Jeff Weitz; Richard Whitlock; Saeed Darvish-Kazim; Justin Debeer; Peter Kavsak; Clive Kearon; Richard Mizera; Martin O'Donnell; Matthew McQueen; Jehonathan Pinthus; Sebastian Ribas; Marko Simunovic; Vikas Tandon; Tomas Vanhelder; Mitchell Winemaker; Hertzel Gerstein; Sarah McDonald; Paul O'Bryne; Ameen Patel; James Paul; Zubin Punthakee; Karen Raymer; Omid Salehian; Fred Spencer; Stephen Walter; Andrew Worster; Anthony Adili; Catherine Clase; Deborah Cook; Mark Crowther; James Douketis; Azim Gangji; Paul Jackson; Wendy Lim; Peter Lovrics; Sergio Mazzadi; William Orovan; Jill Rudkowski; Mark Soth; Maria Tiboni; Rey Acedillo; Amit Garg; Ainslie Hildebrand; Ngan Lam; Danielle Macneil; Marko Mrkobrada; Pavel S Roshanov; Sadeesh K Srinathan; Clare Ramsey; Philip St John; Laurel Thorlacius; Faisal S Siddiqui; Hilary P Grocott; Andrew McKay; Trevor W R Lee; Ryan Amadeo; Duane Funk; Heather McDonald; James Zacharias; Juan Carlos Villar; Olga Lucía Cortés; Maria Stella Chaparro; Skarlett Vásquez; Alvaro Castañeda; Silvia Ferreira; Pierre Coriat; Denis Monneret; Jean Pierre Goarin; Cristina Ibanez Esteve; Catherine Royer; Georges Daas; Matthew T V Chan; Gordon Y S Choi; Tony Gin; Lydia C W Lit; Denis Xavier; Alben Sigamani; Atiya Faruqui; Radhika Dhanpal; Smitha Almeida; Joseph Cherian; Sultana Furruqh; Valsa Abraham; Lalita Afzal; Preetha George; Shaveta Mala; Holger Schünemann; Paola Muti; Enrico Vizza; C Y Wang; G S Y Ong; Marzida Mansor; Alvin S B Tan; Ina I Shariffuddin; V Vasanthan; N H M Hashim; A Wahab Undok; Ushananthini Ki; Hou Yee Lai; Wan Azman Ahmad; Azad H A Razack; German Malaga; Vanessa Valderrama-Victoria; Javier D Loza-Herrera; Maria De Los Angeles Lazo; Aida Rotta-Rotta; Wojciech Szczeklik; Barbara Sokolowska; Jacek Musial; Jacek Gorka; Pawel Iwaszczuk; Mateusz Kozka; Maciej Chwala; Marcin Raczek; Tomasz Mrowiecki; Bogusz Kaczmarek; Bruce Biccard; Hussein Cassimjee; Dean Gopalan; Theroshnie Kisten; Aine Mugabi; Prebashini Naidoo; Rubeshan Naidoo; Reitze Rodseth; David Skinner; Alex Torborg; Pilar Paniagua; Gerard Urrutia; Mari Luz Maestre; Miquel Santaló; Raúl Gonzalez; Adrià Font; Cecilia Martínez; Xavier Pelaez; Marta De Antonio; Jose Marcial Villamor; Jesús Alvarez García; Maria José Ferré; Ekaterina Popova; Pablo Alonso-Coello; Ignacio Garutti; Patricia Cruz; Carmen Fernández; Maria Palencia; Susana Díaz; Teresa Del Castillo; Alberto Varela; Angeles de Miguel; Manuel Muñoz; Patricia Piñeiro; Gabriel Cusati; Maria Del Barrio; Maria José Membrillo; David Orozco; Fidel Reyes; Robert J Sapsford; Julian Barth; Julian Scott; Alistair Hall; Simon Howell; Michaela Lobley; Janet Woods; Susannah Howard; Joanne Fletcher; Nikki Dewhirst; C Williams; A Rushton; I Welters; M Leuwer; Rupert Pearse; Gareth Ackland; Ahsun Khan; Edyta Niebrzegowska; Sally Benton; Andrew Wragg; Andrew Archbold; Amanda Smith; Eleanor McAlees; Cheryl Ramballi; Neil Macdonald; Marta Januszewska; Robert Stephens; Anna Reyes; Laura Gallego Paredes; Pervez Sultan; David Cain; John Whittle; Ana Gutierrez Del Arroyo; Daniel I Sessler; Andrea Kurz; Zhuo Sun; Patrick S Finnegan; Cameron Egan; Hooman Honar; Aram Shahinyan; Krit Panjasawatwong; Alexander Y Fu; Sihe Wang; Edmunds Reineks; Peter Nagele; Jane Blood; Megan Kalin; David Gibson; Troy Wildes
Journal:  Anesthesiology       Date:  2014-03       Impact factor: 7.892

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Review 4.  A review of recent advances in data analytics for post-operative patient deterioration detection.

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5.  Association between complications and death within 30 days after noncardiac surgery.

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6.  Effects of the intermediate care unit on the oldest-old general surgical patients: a retrospective, pre- and postintervention study.

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Journal:  Aging Clin Exp Res       Date:  2020-07-31       Impact factor: 3.636

7.  Knowledge Gaps in the Perioperative Management of Adults with Obstructive Sleep Apnea and Obesity Hypoventilation Syndrome. An Official American Thoracic Society Workshop Report.

Authors:  Najib T Ayas; Cheryl R Laratta; John M Coleman; Anthony G Doufas; Matthias Eikermann; Peter C Gay; Daniel J Gottlieb; Indira Gurubhagavatula; David R Hillman; Roop Kaw; Atul Malhotra; Babak Mokhlesi; Timothy I Morgenthaler; Sairam Parthasarathy; Satya Krishna Ramachandran; Kingman P Strohl; Patrick J Strollo; Michael J Twery; Phyllis C Zee; Frances F Chung
Journal:  Ann Am Thorac Soc       Date:  2018-02

8.  A prospective study of post-cesarean delivery hypoxia after spinal anesthesia with intrathecal morphine 150μg.

Authors:  Karim S Ladha; Rie Kato; Lawrence C Tsen; Brian T Bateman; Toshiyuki Okutomi
Journal:  Int J Obstet Anesth       Date:  2017-06-20       Impact factor: 2.603

Review 9.  Anastomotic Leak: Toward an Understanding of Its Root Causes.

Authors:  John C Alverdy; Hans Martin Schardey
Journal:  J Gastrointest Surg       Date:  2021-06-07       Impact factor: 3.452

Review 10.  Opioid-Induced In-Hospital Deaths: A 10-Year Review of Australian Coroners' Cases Exploring Similarities and Lessons Learnt.

Authors:  Nicholas Smoker; Ben Kirsopp; Jacinta Lee Johnson
Journal:  Pharmacy (Basel)       Date:  2021-05-07
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