Literature DB >> 34100248

Anastomotic Leak: Toward an Understanding of Its Root Causes.

John C Alverdy1, Hans Martin Schardey2,3.   

Abstract

BACKGROUND: When an anastomotic leak is discussed at a typical surgical morbidity and mortality conference, it is often presented as a due to an error in surgical technique involving ischemia, tension, or device failure. Here we assert that without direct visual analysis of the leak site and its tissue histology, an ex post facto claim that an anastomotic leak is due to an error in surgical technique remains speculative.
METHODS: The arguments and rationale used to conclude that an anastomotic leak is due to an error in surgical technique are critically reviewed and assessed for their validity.
RESULTS: No case series or literature exists in which a root cause analysis has been carried out with visual and tissue level evidence to determine the root cause(s) of an anastomotic leak.
CONCLUSIONS: At the individual case level, declaring that an anastomotic leak is due to an error in surgical technique without clear and compelling evidence either visually and/or at the tissue level to substantiate such a claim remains speculative.
© 2021. The Society for Surgery of the Alimentary Tract.

Entities:  

Keywords:  Anastomotic leak; Dogma; Ischemia; Root causes

Mesh:

Year:  2021        PMID: 34100248      PMCID: PMC8815793          DOI: 10.1007/s11605-021-05048-4

Source DB:  PubMed          Journal:  J Gastrointest Surg        ISSN: 1091-255X            Impact factor:   3.452


  74 in total

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2.  Novel de novo synthesized phosphate carrier compound ABA-PEG20k-Pi20 suppresses collagenase production in Enterococcus faecalis and prevents colonic anastomotic leak in an experimental model.

Authors:  M Wiegerinck; S K Hyoju; J Mao; A Zaborin; C Adriaansens; E Salzman; N H Hyman; O Zaborina; H van Goor; J C Alverdy
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3.  Correlation between indocyanine green visualization time in the gastric tube and postoperative endoscopic assessment of the anastomosis after esophageal surgery.

Authors:  Hiroyuki Kitagawa; Tsutomu Namikawa; Jun Iwabu; Keiichiro Yokota; Sunao Uemura; Masaya Munekage; Kazuhiro Hanazaki
Journal:  Surg Today       Date:  2020-05-22       Impact factor: 2.549

4.  Neural correlates of the volitional regulation of the desire for food.

Authors:  M Hollmann; L Hellrung; B Pleger; H Schlögl; S Kabisch; M Stumvoll; A Villringer; A Horstmann
Journal:  Int J Obes (Lond)       Date:  2011-06-28       Impact factor: 5.095

Review 5.  Single layer versus double layer suture anastomosis of the gastrointestinal tract.

Authors:  Muhammad S Sajid; Muhammed Rafay Sameem Siddiqui; Mirza K Baig
Journal:  Cochrane Database Syst Rev       Date:  2012-01-18

6.  The influence of anastomotic leakage for rectal cancer oncologic outcome: A systematic review and meta-analysis.

Authors:  Jianguo Yang; Qingwei Chen; Li Jindou; Yong Cheng
Journal:  J Surg Oncol       Date:  2020-04-03       Impact factor: 3.454

Review 7.  Intraoperative indocyanine green fluorescence angiography to prevent anastomotic leak after low anterior resection for rectal cancer: a meta-analysis.

Authors:  Yu Shen; Tinghan Yang; Jinliang Yang; Wenjian Meng; Ziqiang Wang
Journal:  ANZ J Surg       Date:  2020-03-11       Impact factor: 1.872

8.  Intestinal tissues induce an SNP mutation in Pseudomonas aeruginosa that enhances its virulence: possible role in anastomotic leak.

Authors:  Andrea D Olivas; Benjamin D Shogan; Vesta Valuckaite; Alexander Zaborin; Natalya Belogortseva; Mark Musch; Folker Meyer; William L Trimble; Gary An; Jack Gilbert; Olga Zaborina; John C Alverdy
Journal:  PLoS One       Date:  2012-08-31       Impact factor: 3.240

9.  Hypoxemia Within the First 3 Postoperative Days Is Associated With Increased 1-Year Postoperative Mortality After Adjusting for Perioperative Opioids and Other Confounders.

Authors:  Karsten Bartels; Alexander Kaizer; Leslie Jameson; Kenneth Bullard; Colleen Dingmann; Ana Fernandez-Bustamante
Journal:  Anesth Analg       Date:  2020-08       Impact factor: 6.627

10.  More than half of hypoxemia cases occurred during the recovery period after completion of esophagogastroduodenoscopy with planned moderate sedation.

Authors:  Yukihiro Shirota; Yoshimi Hirase; Tsuyoshi Suda; Masaki Miyazawa; Yuji Hodo; Tokio Wakabayashi
Journal:  Sci Rep       Date:  2020-03-09       Impact factor: 4.379

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  1 in total

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Authors:  J Kinross
Journal:  Tech Coloproctol       Date:  2022-09       Impact factor: 3.699

  1 in total

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