Literature DB >> 26161377

Multivariate Analysis of Risk Factors Associated With the Nonreversal Ileostomy Following Sphincter-Preserving Surgery for Rectal Cancer.

Young Ah Kim1, Gil Jae Lee1, Sung Won Park1, Won-Suk Lee1, Jeong-Heum Baek1.   

Abstract

PURPOSE: A loop ileostomy is used to protect an anastomosis after anal sphincter-preserving surgery, especially in patients with low rectal cancer, but little information is available concerning risk factors associated with a nonreversal ileostomy. The purpose of this study was to identify risk factors of ileostomy nonreversibility after a sphincter-saving resection for rectal cancer.
METHODS: Six hundred seventy-nine (679) patients with rectal cancer who underwent sphincter-preserving surgery between January 2004 and December 2011 were evaluated retrospectively. Of the 679, 135 (19.9%) underwent a defunctioning loop ileostomy of temporary intent, and these patients were divided into two groups, that is, a reversal group (RG, 112 patients) and a nonreversal group (NRG, 23 patients) according to the reversibility of the ileostomy.
RESULTS: In 23 of the 135 rectal cancer patients (17.0%) that underwent a diverting ileostomy, stoma reversal was not possible for the following reasons; stage IV rectal cancer (11, 47.8%), poor tone of the anal sphincter (4, 17.4%), local recurrence (2, 8.7%), anastomotic leakage (1, 4.3%), radiation proctitis (1, 4.3%), and patient refusal (4, 17.4%). The independent risk factors of the nonreversal group were anastomotic leakage or fistula, stage IV cancer, local recurrence, and comorbidity.
CONCLUSION: Postoperative complications such as anastomotic leakage or fistula, advanced primary disease (stage IV), local recurrence and comorbidity were identified as risk factors of a nonreversal ileostomy. These factors should be considered when drafting prudential guidelines for ileostomy closure.

Entities:  

Keywords:  Ileostomy; Rectal cancer; Sphincter-preserving surgery

Year:  2015        PMID: 26161377      PMCID: PMC4496460          DOI: 10.3393/ac.2015.31.3.98

Source DB:  PubMed          Journal:  Ann Coloproctol        ISSN: 2287-9714


  23 in total

1.  The indications for a diverting stoma in low anterior resection for rectal cancer: a prospective multicentre study of 222 patients from Japanese cancer centers.

Authors:  A Shiomi; M Ito; N Saito; T Hirai; M Ohue; Y Kubo; Y Takii; T Sudo; M Kotake; Y Moriya
Journal:  Colorectal Dis       Date:  2011-12       Impact factor: 3.788

2.  Characteristics and risk factors associated with permanent stomas after sphincter-saving resection for rectal cancer.

Authors:  Seok In Seo; Chang Sik Yu; Gwon Sik Kim; Jong Lyul Lee; Yong Sik Yoon; Chan Wook Kim; Seok-Byung Lim; Jin Cheon Kim
Journal:  World J Surg       Date:  2013-10       Impact factor: 3.352

3.  Delayed anastomotic leakage following sphincter-preserving surgery for rectal cancer.

Authors:  Ui Sup Shin; Chan Wook Kim; Chang Sik Yu; Jin Cheon Kim
Journal:  Int J Colorectal Dis       Date:  2010-04-13       Impact factor: 2.571

4.  Co-morbidity leads to altered treatment and worse survival of elderly patients with colorectal cancer.

Authors:  V E P P Lemmens; M L G Janssen-Heijnen; C D G W Verheij; S Houterman; O J Repelaer van Driel; J W W Coebergh
Journal:  Br J Surg       Date:  2005-05       Impact factor: 6.939

Review 5.  Postoperative complications following surgery for rectal cancer.

Authors:  Bogdan C Paun; Scott Cassie; Anthony R MacLean; Elijah Dixon; W Donald Buie
Journal:  Ann Surg       Date:  2010-05       Impact factor: 12.969

6.  Ultimate fate of the leaking intestinal anastomosis: does leak mean permanent stoma?

Authors:  Todd D Francone; Abdulaziz Saleem; Thomas A Read; Patricia L Roberts; Peter W Marcello; David J Schoetz; Rocco Ricciardi
Journal:  J Gastrointest Surg       Date:  2010-04-07       Impact factor: 3.452

7.  What is the risk for a permanent stoma after low anterior resection of the rectum for cancer? A six-year follow-up of a multicenter trial.

Authors:  Rickard Lindgren; Olof Hallböök; Jörgen Rutegård; Rune Sjödahl; Peter Matthiessen
Journal:  Dis Colon Rectum       Date:  2011-01       Impact factor: 4.585

8.  Loop ileostomy following anterior resection: is it really temporary?

Authors:  G G David; J P Slavin; S Willmott; D J Corless; A U Khan; C R Selvasekar
Journal:  Colorectal Dis       Date:  2009-02-17       Impact factor: 3.788

9.  The outcome following sphincter-saving resection and abdominoperineal resection for low rectal cancer.

Authors:  N S Williams; P Durdey; D Johnston
Journal:  Br J Surg       Date:  1985-08       Impact factor: 6.939

10.  Risk factors of permanent stomas in patients with rectal cancer after low anterior resection with temporary stomas.

Authors:  Chul Min Lee; Jung Wook Huh; Yoon Ah Park; Yong Beom Cho; Hee Cheol Kim; Seong Hyeon Yun; Woo Yong Lee; Ho-Kyung Chun
Journal:  Yonsei Med J       Date:  2015-03       Impact factor: 2.759

View more
  6 in total

1.  The fate of preserved sphincter in rectal cancer patients.

Authors:  Ri Na Yoo; Gun Kim; Bong-Hyeon Kye; Hyeon-Min Cho; HyungJin Kim
Journal:  Int J Colorectal Dis       Date:  2018-03-12       Impact factor: 2.571

2.  The effect of biofeedback training on intestinal function among patients with middle and low rectal cancer: a randomized controlled study.

Authors:  Li Liu; Xiaodan Wu; Qianwen Liu; Caixing Tang; Baojia Luo; Yujing Fang; Zhizhong Pan; Desen Wan; Meichun Zheng
Journal:  Ann Transl Med       Date:  2019-11

3.  Stoma Creation After Surgery for Rectal Cancer: Temporary or Permanent?

Authors:  Jung Wook Huh
Journal:  Ann Coloproctol       Date:  2015-06

4.  Fortune of temporary ileostomies in patients treated with laparoscopic low anterior resection for rectal cancer.

Authors:  Mustafa Haksal; Nuri Okkabaz; Ali Emre Atici; Osman Civil; Yasar Ozdenkaya; Ayhan Erdemir; Nihat Aksakal; Mustafa Oncel
Journal:  Ann Surg Treat Res       Date:  2016-12-30       Impact factor: 1.859

5.  Early closure of defunctioning stoma increases complications related to stoma closure after concurrent chemoradiotherapy and low anterior resection in patients with rectal cancer.

Authors:  Tzu-Chieh Yin; Hsiang-Lin Tsai; Ping-Fu Yang; Wei-Chih Su; Cheng-Jen Ma; Ching-Wen Huang; Ming-Yii Huang; Chun-Ming Huang; Jaw-Yuan Wang
Journal:  World J Surg Oncol       Date:  2017-04-11       Impact factor: 2.754

6.  A nomogram to predict the incidence of permanent stoma in elderly patients with rectal cancer.

Authors:  Chuangkun Li; Xiusen Qin; Zifeng Yang; Wentai Guo; Rongkang Huang; Huaiming Wang; Hui Wang
Journal:  Ann Transl Med       Date:  2021-02
  6 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.