Literature DB >> 25937684

Energy dispersive CdTe and CdZnTe detectors for spectral clinical CT and NDT applications.

W C Barber1, J C Wessel1, E Nygard2, J S Iwanczyk3.   

Abstract

We are developing room temperature compound semiconductor detectors for applications in energy-resolved high-flux single x-ray photon-counting spectral computed tomography (CT), including functional imaging with nanoparticle contrast agents for medical applications and non destructive testing (NDT) for security applications. Energy-resolved photon-counting can provide reduced patient dose through optimal energy weighting for a particular imaging task in CT, functional contrast enhancement through spectroscopic imaging of metal nanoparticles in CT, and compositional analysis through multiple basis function material decomposition in CT and NDT. These applications produce high input count rates from an x-ray generator delivered to the detector. Therefore, in order to achieve energy-resolved single photon counting in these applications, a high output count rate (OCR) for an energy-dispersive detector must be achieved at the required spatial resolution and across the required dynamic range for the application. The required performance in terms of the OCR, spatial resolution, and dynamic range must be obtained with sufficient field of view (FOV) for the application thus requiring the tiling of pixel arrays and scanning techniques. Room temperature cadmium telluride (CdTe) and cadmium zinc telluride (CdZnTe) compound semiconductors, operating as direct conversion x-ray sensors, can provide the required speed when connected to application specific integrated circuits (ASICs) operating at fast peaking times with multiple fixed thresholds per pixel provided the sensors are designed for rapid signal formation across the x-ray energy ranges of the application at the required energy and spatial resolutions, and at a sufficiently high detective quantum efficiency (DQE). We have developed high-flux energy-resolved photon-counting x-ray imaging array sensors using pixellated CdTe and CdZnTe semiconductors optimized for clinical CT and security NDT. We have also fabricated high-flux ASICs with a two dimensional (2D) array of inputs for readout from the sensors. The sensors are guard ring free and have a 2D array of pixels and can be tiled in 2D while preserving pixel pitch. The 2D ASICs have four energy bins with a linear energy response across sufficient dynamic range for clinical CT and some NDT applications. The ASICs can also be tiled in 2D and are designed to fit within the active area of the sensors. We have measured several important performance parameters including; the output count rate (OCR) in excess of 20 million counts per second per square mm with a minimum loss of counts due to pulse pile-up, an energy resolution of 7 keV full width at half maximum (FWHM) across the entire dynamic range, and a noise floor about 20keV. This is achieved by directly interconnecting the ASIC inputs to the pixels of the CdZnTe sensors incurring very little input capacitance to the ASICs. We present measurements of the performance of the CdTe and CdZnTe sensors including the OCR, FWHM energy resolution, noise floor, as well as the temporal stability and uniformity under the rapidly varying high flux expected in CT and NDT applications.

Entities:  

Keywords:  ASIC; CT; CZT; CdTe; X-ray; semiconductor

Year:  2015        PMID: 25937684      PMCID: PMC4415629          DOI: 10.1016/j.nima.2014.10.079

Source DB:  PubMed          Journal:  Nucl Instrum Methods Phys Res A        ISSN: 0168-9002            Impact factor:   1.455


  10 in total

1.  Four multidetector-row helical CT: image quality and volume coverage speed.

Authors:  H Hu; H D He; W D Foley; S H Fox
Journal:  Radiology       Date:  2000-04       Impact factor: 11.105

2.  Noise reduction in spectral CT: reducing dose and breaking the trade-off between image noise and energy bin selection.

Authors:  Shuai Leng; Lifeng Yu; Jia Wang; Joel G Fletcher; Charles A Mistretta; Cynthia H McCollough
Journal:  Med Phys       Date:  2011-09       Impact factor: 4.071

3.  An analytical model of the effects of pulse pileup on the energy spectrum recorded by energy resolved photon counting x-ray detectors.

Authors:  Katsuyuki Taguchi; Eric C Frey; Xiaolan Wang; Jan S Iwanczyk; William C Barber
Journal:  Med Phys       Date:  2010-08       Impact factor: 4.071

4.  Photon counting computed tomography: concept and initial results.

Authors:  Polad M Shikhaliev; Tong Xu; Sabee Molloi
Journal:  Med Phys       Date:  2005-02       Impact factor: 4.071

5.  Beam hardening artefacts in computed tomography with photon counting, charge integrating and energy weighting detectors: a simulation study.

Authors:  Polad M Shikhaliev
Journal:  Phys Med Biol       Date:  2005-12-01       Impact factor: 3.609

6.  Experimental feasibility of multi-energy photon-counting K-edge imaging in pre-clinical computed tomography.

Authors:  J P Schlomka; E Roessl; R Dorscheid; S Dill; G Martens; T Istel; C Bäumer; C Herrmann; R Steadman; G Zeitler; A Livne; R Proksa
Journal:  Phys Med Biol       Date:  2008-07-08       Impact factor: 3.609

7.  Segmentation and quantification of materials with energy discriminating computed tomography: a phantom study.

Authors:  Huy Q Le; Sabee Molloi
Journal:  Med Phys       Date:  2011-01       Impact factor: 4.071

8.  Modeling the performance of a photon counting x-ray detector for CT: energy response and pulse pileup effects.

Authors:  Katsuyuki Taguchi; Mengxi Zhang; Eric C Frey; Xiaolan Wang; Jan S Iwanczyk; Einar Nygard; Neal E Hartsough; Benjamin M W Tsui; William C Barber
Journal:  Med Phys       Date:  2011-02       Impact factor: 4.071

9.  CT scanning: patterns of use and dose.

Authors:  F A Mettler; P W Wiest; J A Locken; C A Kelsey
Journal:  J Radiol Prot       Date:  2000-12       Impact factor: 1.394

10.  Photon Counting Energy Dispersive Detector Arrays for X-ray Imaging.

Authors:  Jan S Iwanczyk; Einar Nygård; Oded Meirav; Jerry Arenson; William C Barber; Neal E Hartsough; Nail Malakhov; Jan C Wessel
Journal:  IEEE Trans Nucl Sci       Date:  2009       Impact factor: 1.679

  10 in total
  6 in total

1.  Spectral Photon Counting CT: Imaging Algorithms and Performance Assessment.

Authors:  Adam S Wang; Norbert J Pelc
Journal:  IEEE Trans Radiat Plasma Med Sci       Date:  2020-07-07

2.  Ballistic Deficit Pulse Processing in Cadmium-Zinc-Telluride Pixel Detectors for High-Flux X-ray Measurements.

Authors:  Antonino Buttacavoli; Fabio Principato; Gaetano Gerardi; Manuele Bettelli; Andrea Zappettini; Paul Seller; Matthew C Veale; Silvia Zanettini; Leonardo Abbene
Journal:  Sensors (Basel)       Date:  2022-04-29       Impact factor: 3.847

Review 3.  Tutorial on X-ray photon counting detector characterization.

Authors:  Liqiang Ren; Bin Zheng; Hong Liu
Journal:  J Xray Sci Technol       Date:  2018       Impact factor: 1.535

Review 4.  Cadmium Telluride Semiconductor Detector for Improved Spatial and Energy Resolution Radioisotopic Imaging.

Authors:  Samira Abbaspour; Babak Mahmoudian; Jalil Pirayesh Islamian
Journal:  World J Nucl Med       Date:  2017 Apr-Jun

5.  Incomplete Charge Collection at Inter-Pixel Gap in Low- and High-Flux Cadmium Zinc Telluride Pixel Detectors.

Authors:  Antonino Buttacavoli; Fabio Principato; Gaetano Gerardi; Donato Cascio; Giuseppe Raso; Manuele Bettelli; Andrea Zappettini; Paul Seller; Matthew C Veale; Leonardo Abbene
Journal:  Sensors (Basel)       Date:  2022-02-13       Impact factor: 3.576

6.  Energy Recovery of Multiple Charge Sharing Events in Room Temperature Semiconductor Pixel Detectors.

Authors:  Antonino Buttacavoli; Gaetano Gerardi; Fabio Principato; Marcello Mirabello; Donato Cascio; Giuseppe Raso; Manuele Bettelli; Andrea Zappettini; Paul Seller; Matthew C Veale; Leonardo Abbene
Journal:  Sensors (Basel)       Date:  2021-05-25       Impact factor: 3.576

  6 in total

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