Borjan A Gagoski1,2, Berkin Bilgic2,3, Cornelius Eichner3,4, Himanshu Bhat5, P Ellen Grant1,2, Lawrence L Wald2,3,6, Kawin Setsompop2,3. 1. Fetal-Neonatal Neuroimaging & Developmental Science Center, Boston Children's Hospital, Boston, MA, USA. 2. Department of Radiology, Harvard Medical School, Boston, MA, USA. 3. Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, USA. 4. Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany. 5. Siemens Medical Solutions USA Inc., Charlestown, MA, USA. 6. Harvard-MIT Health Sciences and Technology, Cambridge, MA, USA.
Abstract
PURPOSE: To enable highly accelerated RARE/Turbo Spin Echo (TSE) imaging using Simultaneous MultiSlice (SMS) Wave-CAIPI acquisition with reduced g-factor penalty. METHODS: SMS Wave-CAIPI incurs slice shifts across simultaneously excited slices while playing sinusoidal gradient waveforms during the readout of each encoding line. This results in an efficient k-space coverage that spreads aliasing in all three dimensions to fully harness the encoding power of coil sensitivities. The novel MultiPINS radiofrequency (RF) pulses dramatically reduce the power deposition of multiband (MB) refocusing pulse, thus allowing high MB factors within the Specific Absorption Rate (SAR) limit. RESULTS: Wave-CAIPI acquisition with MultiPINS permits whole brain coverage with 1 mm isotropic resolution in 70 s at effective MB factor 13, with maximum and average g-factor penalties of gmax = 1.34 and gavg = 1.12, and without √R penalty. With blipped-CAIPI, the g-factor performance was degraded to gmax = 3.24 and gavg = 1.42; a 2.4-fold increase in gmax relative to Wave-CAIPI. At this MB factor, the SAR of the MultiBand and PINS pulses are 4.2 and 1.9 times that of the MultiPINS pulse, while the peak RF power are 19.4 and 3.9 times higher. CONCLUSION: Combination of the two technologies, Wave-CAIPI and MultiPINS pulse, enables highly accelerated RARE/TSE imaging with low SNR penalty at reduced SAR.
PURPOSE: To enable highly accelerated RARE/Turbo Spin Echo (TSE) imaging using Simultaneous MultiSlice (SMS) Wave-CAIPI acquisition with reduced g-factor penalty. METHODS:SMS Wave-CAIPI incurs slice shifts across simultaneously excited slices while playing sinusoidal gradient waveforms during the readout of each encoding line. This results in an efficient k-space coverage that spreads aliasing in all three dimensions to fully harness the encoding power of coil sensitivities. The novel MultiPINS radiofrequency (RF) pulses dramatically reduce the power deposition of multiband (MB) refocusing pulse, thus allowing high MB factors within the Specific Absorption Rate (SAR) limit. RESULTS: Wave-CAIPI acquisition with MultiPINS permits whole brain coverage with 1 mm isotropic resolution in 70 s at effective MB factor 13, with maximum and average g-factor penalties of gmax = 1.34 and gavg = 1.12, and without √R penalty. With blipped-CAIPI, the g-factor performance was degraded to gmax = 3.24 and gavg = 1.42; a 2.4-fold increase in gmax relative to Wave-CAIPI. At this MB factor, the SAR of the MultiBand and PINS pulses are 4.2 and 1.9 times that of the MultiPINS pulse, while the peak RF power are 19.4 and 3.9 times higher. CONCLUSION: Combination of the two technologies, Wave-CAIPI and MultiPINS pulse, enables highly accelerated RARE/TSE imaging with low SNR penalty at reduced SAR.
Authors: K Setsompop; J Cohen-Adad; B A Gagoski; T Raij; A Yendiki; B Keil; V J Wedeen; L L Wald Journal: Neuroimage Date: 2012-06-23 Impact factor: 6.556
Authors: Kawin Setsompop; Borjan A Gagoski; Jonathan R Polimeni; Thomas Witzel; Van J Wedeen; Lawrence L Wald Journal: Magn Reson Med Date: 2011-08-19 Impact factor: 4.668
Authors: Kamil Uğurbil; Junqian Xu; Edward J Auerbach; Steen Moeller; An T Vu; Julio M Duarte-Carvajalino; Christophe Lenglet; Xiaoping Wu; Sebastian Schmitter; Pierre Francois Van de Moortele; John Strupp; Guillermo Sapiro; Federico De Martino; Dingxin Wang; Noam Harel; Michael Garwood; Liyong Chen; David A Feinberg; Stephen M Smith; Karla L Miller; Stamatios N Sotiropoulos; Saad Jbabdi; Jesper L R Andersson; Timothy E J Behrens; Matthew F Glasser; David C Van Essen; Essa Yacoub Journal: Neuroimage Date: 2013-05-21 Impact factor: 6.556
Authors: Stephen F Cauley; Kawin Setsompop; Berkin Bilgic; Himanshu Bhat; Borjan Gagoski; Lawrence L Wald Journal: Magn Reson Med Date: 2016-10-21 Impact factor: 4.668
Authors: Daniel Polak; Stephen Cauley; Susie Y Huang; Maria Gabriela Longo; John Conklin; Berkin Bilgic; Ned Ohringer; Esther Raithel; Peter Bachert; Lawrence L Wald; Kawin Setsompop Journal: J Magn Reson Imaging Date: 2019-02-08 Impact factor: 4.813
Authors: Itthi Chatnuntawech; Patrick McDaniel; Stephen F Cauley; Borjan A Gagoski; Christian Langkammer; Adrian Martin; P Ellen Grant; Lawrence L Wald; Kawin Setsompop; Elfar Adalsteinsson; Berkin Bilgic Journal: NMR Biomed Date: 2016-06-22 Impact factor: 4.044
Authors: Huihui Ye; Stephen F Cauley; Borjan Gagoski; Berkin Bilgic; Dan Ma; Yun Jiang; Yiping P Du; Mark A Griswold; Lawrence L Wald; Kawin Setsompop Journal: Magn Reson Med Date: 2016-05-25 Impact factor: 4.668