Literature DB >> 25615511

The effects of extending the spectral information acquired by a photon-counting detector for spectral CT.

Taly Gilat Schmidt1, Kevin C Zimmerman, Emil Y Sidky.   

Abstract

Photon-counting x-ray detectors with pulse-height analysis provide spectral information that may improve material decomposition and contrast-to-noise ratio (CNR) in CT images. The number of energy measurements that can be acquired simultaneously on a detector pixel is equal to the number of comparator channels. Some spectral CT designs have a limited number of comparator channels, due to the complexity of readout electronics. The spectral information could be extended by changing the comparator threshold levels over time, sub pixels, or view angle. However, acquiring more energy measurements than comparator channels increases the noise and/or dose, due to differences in noise correlations across energy measurements and decreased dose utilisation. This study experimentally quantified the effects of acquiring more energy measurements than comparator channels using a bench-top spectral CT system. An analytical and simulation study modeling an ideal detector investigated whether there was a net benefit for material decomposition or optimal energy weighting when acquiring more energy measurements than comparator channels. Experimental results demonstrated that in a two-threshold acquisition, acquiring the high-energy measurement independently from the low-energy measurement increased noise standard deviation in material-decomposition basis images by factors of 1.5-1.7 due to changes in covariance between energy measurements. CNR in energy-weighted images decreased by factors of 0.92-0.71. Noise standard deviation increased by an additional factor of [Formula: see text] due to reduced dose utilisation. The results demonstrated no benefit for two-material decomposition noise or energy-weighted CNR when acquiring more energy measurements than comparator channels. Understanding the noise penalty of acquiring more energy measurements than comparator channels is important for designing spectral detectors and for designing experiments and interpreting data from prototype systems with a limited number of comparator channels.

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Year:  2015        PMID: 25615511      PMCID: PMC4339093          DOI: 10.1088/0031-9155/60/4/1583

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  15 in total

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8.  Estimator for photon counting energy selective x-ray imaging with multibin pulse height analysis.

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  8 in total

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4.  Spectral prior image constrained compressed sensing (spectral PICCS) for photon-counting computed tomography.

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Review 5.  Pulmonary CT and MRI phenotypes that help explain chronic pulmonary obstruction disease pathophysiology and outcomes.

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6.  A neural network-based method for spectral distortion correction in photon counting x-ray CT.

Authors:  Mengheng Touch; Darin P Clark; William Barber; Cristian T Badea
Journal:  Phys Med Biol       Date:  2016-07-29       Impact factor: 3.609

7.  Evaluation of conventional imaging performance in a research whole-body CT system with a photon-counting detector array.

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8.  CAMPO Precision128 Max ENERGY Spectrum CT Combined with Multiple Parameters to Evaluate the Benign and Malignant Pleural Effusion.

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  8 in total

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