Literature DB >> 25488316

Clinical pharmacists' review of surgical antimicrobial prophylaxis in a tertiary hospital in Abu Dhabi.

Mohamed El Hassan1, Asim Ahmed Elnour, Farah Hamad Farah, Abdulla Shehab, Naama M Al Kalbani, Sahar Asim, Omer Abdulla Shehab, Rauda Abdulla.   

Abstract

BACKGROUND: There is a lack of evidence to support standard of care and concordance with surgical antimicrobial prophylaxis (SAP) guidelines in our setting. There is an opportunity for clinical pharmacists to facilitate this process across all surgical disciplines.
OBJECTIVE: To assess adherence of surgeons to SAP guidelines.
METHOD: This was a retrospective study of 250 patients who underwent surgery during 2012 in Mafraq Hospital, Abu Dhabi. We evaluated prescribing of SAP, antimicrobial selection, first-dose timing, dose interval, treatment duration and adherence of surgeons to local hospital guidelines.
RESULTS: We reviewed 250 patients (193 were male and 57 were female, mean age 36 ± 1.2 years); 54 % had elective operations and 46 % underwent emergency surgery. Adherence to hospital guidelines was 32.1 %. Antimicrobial selection, timing of the first dose, dosage interval and treatment duration were concordant with the hospital guidelines in 26, 31 and 40.3 % of cases, respectively. Main barriers to adherence to hospital guidelines were lack of awareness and education.
CONCLUSIONS: The present study indicated poor adherence to the SAP guidelines. The timing of administration of SAP was not appropriate in two-thirds of the patients and more than half received more than three doses of SAP inappropriately. Continuing medical education should target antimicrobial prophylaxis (selection, timing and duration), clinical pharmacy antibiotic services and cyclic auditing.

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Year:  2014        PMID: 25488316     DOI: 10.1007/s11096-014-0045-4

Source DB:  PubMed          Journal:  Int J Clin Pharm


  8 in total

1.  Evaluation of prophylactic antibiotic administration at the surgical ward of a major referral hospital, Islamic Republic of Iran.

Authors:  G Vessal; S Namazi; M A Davarpanah; F Foroughinia
Journal:  East Mediterr Health J       Date:  2011-08       Impact factor: 1.628

2.  Adherence to guidelines for antibiotic prophylaxis in general surgery: a critical appraisal.

Authors:  C E Tourmousoglou; E Ch Yiannakopoulou; V Kalapothaki; J Bramis; J St Papadopoulos
Journal:  J Antimicrob Chemother       Date:  2007-11-12       Impact factor: 5.790

Review 3.  Is antibiotic prophylaxis in surgery a generally effective intervention? Testing a generic hypothesis over a set of meta-analyses.

Authors:  Russell J Bowater; Seonaid A Stirling; Richard J Lilford
Journal:  Ann Surg       Date:  2009-04       Impact factor: 12.969

4.  A Study on the Usage Pattern of Antimicrobial Agents for the Prevention of Surgical Site Infections (SSIs) in a Tertiary Care Teaching Hospital.

Authors:  Afzal Khan A K; Mirshad P V; Mohammed Rafiuddin Rashed; Gausia Banu
Journal:  J Clin Diagn Res       Date:  2013-02-27

5.  Clinical practice guidelines for antimicrobial prophylaxis in surgery.

Authors:  Dale W Bratzler; E Patchen Dellinger; Keith M Olsen; Trish M Perl; Paul G Auwaerter; Maureen K Bolon; Douglas N Fish; Lena M Napolitano; Robert G Sawyer; Douglas Slain; James P Steinberg; Robert A Weinstein
Journal:  Am J Health Syst Pharm       Date:  2013-02-01       Impact factor: 2.637

Review 6.  [Prevention of surgical site infection in abdominal surgery. A critical review of the evidence].

Authors:  Jaime Ruiz Tovar; Josep M Badia
Journal:  Cir Esp       Date:  2014-01-09       Impact factor: 1.653

Review 7.  Adherence to surgical care improvement project measures and post-operative surgical site infections.

Authors:  Samir S Awad
Journal:  Surg Infect (Larchmt)       Date:  2012-08-22       Impact factor: 2.150

8.  Multistate point-prevalence survey of health care-associated infections.

Authors:  Shelley S Magill; Jonathan R Edwards; Wendy Bamberg; Zintars G Beldavs; Ghinwa Dumyati; Marion A Kainer; Ruth Lynfield; Meghan Maloney; Laura McAllister-Hollod; Joelle Nadle; Susan M Ray; Deborah L Thompson; Lucy E Wilson; Scott K Fridkin
Journal:  N Engl J Med       Date:  2014-03-27       Impact factor: 91.245

  8 in total
  7 in total

1.  An Evaluation of Surgical Prophylaxis Procedures in Turkey: A Multi-Center Point Prevalence Study.

Authors:  Selcuk Kaya; Seyhan Aktas; Seniha Senbayrak; Recep Tekin; Nefise Oztoprak; Firdevs Aksoy; Pinar Firat; Sevinc Yenice; Ahsen Oncul; Alper Gunduz; Semiha Solak; Ayten Kadanali; Sule Eren Cakar; Derya Caglayan; Hava Yilmaz; Ilkay Bozkurt; Tulin Elmaslar; Ayse Sagmak Tartar; Aynur Aynioglu; Nilgun Fidan Kocyigit; Iftihar Koksal
Journal:  Eurasian J Med       Date:  2016-02

2.  [Multicenter study of adherence to guidelines on surgical prophylaxis and the determinants of non-adherence in ArgentinaEstudo multicêntrico sobre a adesão a diretrizes de profilaxia cirúrgica e seus determinantes na Argentina].

Authors:  Viviana M Rodríguez; Liliana Clara; Diana Klajn; Ángel Colque; María Paula Herrera; Patricia Angeleri
Journal:  Rev Panam Salud Publica       Date:  2020-09-23

3.  Analysis of antibiotic surgical prophylaxis in hospitalized children suffering upper and lower extremity injuries.

Authors:  Inese Sviestina; Janis Mozgis; Dzintars Mozgis
Journal:  Int J Clin Pharm       Date:  2016-03-02

4.  Adherence to the guidelines for surgical antimicrobial prophylaxis in a Saudi tertiary care hospital.

Authors:  Yaser M Alahmadi; Raed H Alharbi; Ahmad K Aljabri; Fadwa S Alofi; Omimah A Alshaalani; Baiaan H Alssdi
Journal:  J Taibah Univ Med Sci       Date:  2020-03-05

5.  Assessment of implementation of antibiotic stewardship program in surgical prophylaxis at a secondary care hospital in Ras Al Khaimah, United Arab Emirates.

Authors:  Hessa Saleh Alshehhi; Areeg Anwer Ali; Duaa Salem Jawhar; Essam Mahran Aly; Srinivas Swamy; Manal Abdel Fattah; Khawla Abdullah Drweesh; Azzan Alsaadi
Journal:  Sci Rep       Date:  2021-01-13       Impact factor: 4.379

6.  Why we prescribe antibiotics for too long in the hospital setting: a systematic scoping review.

Authors:  Robin M E Janssen; Anke J M Oerlemans; Johannes G Van Der Hoeven; Jaap Ten Oever; Jeroen A Schouten; Marlies E J L Hulscher
Journal:  J Antimicrob Chemother       Date:  2022-07-28       Impact factor: 5.758

7.  The Effect of Pharmacist-Led Intervention on Surgical Antibacterial Prophylaxis (SAP) at an Orthopedic Unit.

Authors:  Adina Fésüs; Ria Benkő; Mária Matuz; Orsolya Kungler-Gorácz; Márton Á Fésüs; Tamás Bazsó; Zoltán Csernátony; Gábor Kardos
Journal:  Antibiotics (Basel)       Date:  2021-12-09
  7 in total

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