Selcuk Kaya1, Seyhan Aktas2, Seniha Senbayrak3, Recep Tekin4, Nefise Oztoprak5, Firdevs Aksoy6, Pinar Firat7, Sevinc Yenice8, Ahsen Oncul9, Alper Gunduz9, Semiha Solak10, Ayten Kadanali11, Sule Eren Cakar11, Derya Caglayan12, Hava Yilmaz13, Ilkay Bozkurt13, Tulin Elmaslar14, Ayse Sagmak Tartar15, Aynur Aynioglu16, Nilgun Fidan Kocyigit17, Iftihar Koksal1. 1. Department of Infectious Diseases and Microbiology, Karadeniz Technical University School of Medicine, Trabzon; Hospital Infections Prevention and Control Committee, Karadeniz Technical University School of Medicine, Trabzon, Turkey. 2. Hospital Infections Prevention and Control Committee, Karadeniz Technical University School of Medicine, Trabzon, Turkey. 3. Clinic of Infectious Diseases and Clinical Microbiology, Haydarpaşa Numune Training and Research Hospital, İstanbul, Turkey. 4. Department of Infectious Diseases and Clinical Microbiology, Dicle University School of Medicine Diyarbakır, Turkey. 5. Clinic of Infectious Diseases and Clinical Microbiology, Antalya Training and Research Hospital, Antalya, Turkey. 6. Clinic of Infectious Diseases and Clinical Microbiology, Kanuni Training and Research Hospital, Trabzon, Turkey. 7. Clinic of Infectious Diseases and Clinical Microbiology, Keçiören Training and Research Hospital, Ankara, Turkey. 8. Infection Control Committee, Zonguldak Obstetrics and Pediatric Diseases Hospital, Zonguldak, Turkey. 9. Clinic of Infectious Diseases and Clinical Microbiology, Şişli Etfal Training and Research Hospital, İstanbul, Turkey. 10. Clinic of Infectious Diseases and Clinical Microbiology, Yıldırım Beyazıt University, Yenimahalle Training and Research Hospital, Ankara, Turkey. 11. Clinic of Infectious Diseases and Clinical Microbiology, Ümraniye Training and Research Hospital, İstanbul, Turkey. 12. Clinic of Infectious Diseases and Clinical Microbiology, İzmir M. Enver Şenerdem Torbalı Public Hospital, İzmir, Turkey. 13. Clinic of Infectious Diseases and Clinical Microbiology, Ondokuz Mayıs University School of Medicine, Samsun, Turkey. 14. Clinic of Infectious Diseases and Clinical Microbiology, Ardahan State Hospital, Ardahan, Turkey. 15. Clinic of Infectious Diseases and Clinical Microbiology, Cizre State Hospital, Cizre, Turkey. 16. Clinic of Infectious Diseases and Clinical Microbiology, İzmir Kemalpaşa Public Hospital, İzmir, Turkey. 17. Clinic of Infectious Diseases and Clinical Microbiology, Zonguldak Atatürk Public Hospital, Zonguldak, Turkey.
Abstract
OBJECTIVE: The purpose of this study was to evaluate compliance with guidelines in surgical prophylaxis (SP) procedures in Turkey. MATERIALS AND METHODS: A point prevalence study involving 4 university, 5 education and research and 7 public hospitals was performed assessing compliance with guidelines for antibiotic use in SP. Compliance was based on the "Clinical Practice Guidelines for Antimicrobial Surgery (CPGAS) 2013" guideline. RESULTS: Sixteen centers were included in the study, with 166 operations performed at these being evaluated. Parenteral antibiotic for SP was applied in 161 (96.9%) of these. Type of antibiotic was inappropriate in 66 (40.9%) cases and duration of use in 47 (29.1%). The main antibiotics used inappropriately in SP were ceftriaxone, glycopeptides and aminoglycosides. No significant difference was observed between secondary and tertiary hospitals in terms of inappropriate selection. Duration of prophylaxis was also incompatible with guideline recommendations in approximately half of surgical procedures performed in both secondary and tertiary hospitals, however statistical significance was observed between institutions in favor of tertiary hospitals. CONCLUSION: Antibiotics are to a considerable extent used in a manner incompatible with guidelines even in tertiary hospitals in Turkey. It must not be forgotten that several pre-, intra- and postoperative factors can be involved in the development of surgical site infections (SSI), and antibiotics are not the only option available for preventing these. A significant improvement can be achieved in prophylaxis with close observation, educational activities, collaboration with the surgical team and increasing compliance with guidelines. All health institutions must establish and apply their own SP consensus accompanied by the guidelines in order to achieve success in SP.
OBJECTIVE: The purpose of this study was to evaluate compliance with guidelines in surgical prophylaxis (SP) procedures in Turkey. MATERIALS AND METHODS: A point prevalence study involving 4 university, 5 education and research and 7 public hospitals was performed assessing compliance with guidelines for antibiotic use in SP. Compliance was based on the "Clinical Practice Guidelines for Antimicrobial Surgery (CPGAS) 2013" guideline. RESULTS: Sixteen centers were included in the study, with 166 operations performed at these being evaluated. Parenteral antibiotic for SP was applied in 161 (96.9%) of these. Type of antibiotic was inappropriate in 66 (40.9%) cases and duration of use in 47 (29.1%). The main antibiotics used inappropriately in SP were ceftriaxone, glycopeptides and aminoglycosides. No significant difference was observed between secondary and tertiary hospitals in terms of inappropriate selection. Duration of prophylaxis was also incompatible with guideline recommendations in approximately half of surgical procedures performed in both secondary and tertiary hospitals, however statistical significance was observed between institutions in favor of tertiary hospitals. CONCLUSION: Antibiotics are to a considerable extent used in a manner incompatible with guidelines even in tertiary hospitals in Turkey. It must not be forgotten that several pre-, intra- and postoperative factors can be involved in the development of surgical site infections (SSI), and antibiotics are not the only option available for preventing these. A significant improvement can be achieved in prophylaxis with close observation, educational activities, collaboration with the surgical team and increasing compliance with guidelines. All health institutions must establish and apply their own SP consensus accompanied by the guidelines in order to achieve success in SP.
Authors: Mohamed El Hassan; Asim Ahmed Elnour; Farah Hamad Farah; Abdulla Shehab; Naama M Al Kalbani; Sahar Asim; Omer Abdulla Shehab; Rauda Abdulla Journal: Int J Clin Pharm Date: 2014-12-09
Authors: Massimo Sartelli; Therese M Duane; Fausto Catena; Jeffrey M Tessier; Federico Coccolini; Lillian S Kao; Belinda De Simone; Francesco M Labricciosa; Addison K May; Luca Ansaloni; John E Mazuski Journal: Surg Infect (Larchmt) Date: 2016-11-09 Impact factor: 2.150
Authors: Julius C Mwita; Olayinka O Ogunleye; Adesola Olalekan; Aubrey C Kalungia; Amanj Kurdi; Zikria Saleem; Jacqueline Sneddon; Brian Godman Journal: Int J Gen Med Date: 2021-02-18