Inese Sviestina1,2, Janis Mozgis3, Dzintars Mozgis4. 1. University Children's Hospital, Vienibas gatve 45, Riga, 1004, Latvia. inese.sviestina@gmail.com. 2. Faculty of Pharmacy, Riga Stradins University, Riga, Latvia. inese.sviestina@gmail.com. 3. Faculty of Medicine, Riga Stradins University, Riga, Latvia. 4. Public Health and Epidemiology Department, Riga Stradins University, Riga, Latvia.
Abstract
BACKGROUND: Surgical prophylaxis may account for one-third of all antibiotic use in paediatric hospitals. OBJECTIVE: To evaluate the appropriateness of surgical prophylaxis and to analyse adherence of surgeons to surgical prophylaxis guidelines. METHOD: Retrospective study at a university paediatric hospital. Patients younger than 18 years with injuries of lower and upper extremities were included. The study period was from January 1st 2011-December 31st 2013 and January 1st 2001-December 31st 2003. The appropriateness of the antibiotic use was analysed in accordance with international and local guidelines. RESULTS: Antibiotic prophylaxis was needed by 1125 (55.0 %) patients in 2011-2013 and by 816 (44.4 %) patients in 2001-2003. However, it was administered to only 66.0 % of those in need of prophylaxis in 2011-2013 and to 70.8 % of those in 2001-2003. A single antibiotic dose was administered to 73.8 % of those who received antibiotics in 2011-2013 and to 34.1 % of those in 2001-2003. The timing of the first dose was correct in 370 (52.9 %) prescriptions in 2011-2013 and in 10 (20.4 %) prescriptions in 2001-2003. The most often used antibiotics for prophylaxis were cefazolin in 2011-2013 and cefuroxime in 2001-2003. CONCLUSION: Overall adherence rate to the international and hospital guidelines was low, indicating that in order to improve this situation, there is a need for multiple interventions.
BACKGROUND: Surgical prophylaxis may account for one-third of all antibiotic use in paediatric hospitals. OBJECTIVE: To evaluate the appropriateness of surgical prophylaxis and to analyse adherence of surgeons to surgical prophylaxis guidelines. METHOD: Retrospective study at a university paediatric hospital. Patients younger than 18 years with injuries of lower and upper extremities were included. The study period was from January 1st 2011-December 31st 2013 and January 1st 2001-December 31st 2003. The appropriateness of the antibiotic use was analysed in accordance with international and local guidelines. RESULTS: Antibiotic prophylaxis was needed by 1125 (55.0 %) patients in 2011-2013 and by 816 (44.4 %) patients in 2001-2003. However, it was administered to only 66.0 % of those in need of prophylaxis in 2011-2013 and to 70.8 % of those in 2001-2003. A single antibiotic dose was administered to 73.8 % of those who received antibiotics in 2011-2013 and to 34.1 % of those in 2001-2003. The timing of the first dose was correct in 370 (52.9 %) prescriptions in 2011-2013 and in 10 (20.4 %) prescriptions in 2001-2003. The most often used antibiotics for prophylaxis were cefazolin in 2011-2013 and cefuroxime in 2001-2003. CONCLUSION: Overall adherence rate to the international and hospital guidelines was low, indicating that in order to improve this situation, there is a need for multiple interventions.
Authors: Mohamed El Hassan; Asim Ahmed Elnour; Farah Hamad Farah; Abdulla Shehab; Naama M Al Kalbani; Sahar Asim; Omer Abdulla Shehab; Rauda Abdulla Journal: Int J Clin Pharm Date: 2014-12-09
Authors: Dale W Bratzler; E Patchen Dellinger; Keith M Olsen; Trish M Perl; Paul G Auwaerter; Maureen K Bolon; Douglas N Fish; Lena M Napolitano; Robert G Sawyer; Douglas Slain; James P Steinberg; Robert A Weinstein Journal: Am J Health Syst Pharm Date: 2013-02-01 Impact factor: 2.637
Authors: Amir Khoshbin; Jeannette P So; Ilyas S Aleem; Derek Stephens; Anne G Matlow; James G Wright Journal: Ann Surg Date: 2015-08 Impact factor: 12.969