Literature DB >> 17999981

Adherence to guidelines for antibiotic prophylaxis in general surgery: a critical appraisal.

C E Tourmousoglou1, E Ch Yiannakopoulou, V Kalapothaki, J Bramis, J St Papadopoulos.   

Abstract

OBJECTIVES: To evaluate the adherence of general surgeons to guidelines for antimicrobial prophylaxis. This study was held from January 2000 until October 2000 in a General Surgery Clinic in a hospital in Athens, Greece.
METHODS: Eight hundred and ninety-eight patients were enrolled and operated on electively. Questionnaires concerning demographic data, health status, type of surgery (clean and clean-contaminated) and parameters of antibiotic prophylaxis (antibiotic choice, route, dose, timing of first dose, timing of operative redosing and duration of prophylaxis) were completed.
RESULTS: Of the patients, 44.8% underwent a clean surgical operation and 55.2% underwent a clean-contaminated surgical operation. Inguinal hernia repair and laparoscopic cholecystectomy were the commonest operations in each category. Second-generation cephalosporins were the most frequently prescribed antibiotics, in 67%. Although, only 78.5% of procedures required prophylaxis, it was administered in 97.5%, so it was not justified and inappropriately administered in 19%. It was revealed that 100% of patients received antibiotic prophylaxis on time. The choice of antimicrobial agent was appropriate in 70% and the duration of prophylaxis was optimal in 36.3%. The overall compliance rate of surgeons with guidelines for antibiotic prophylaxis was 36.3%.
CONCLUSIONS: Adherence to separate aspects of guidelines for surgical prophylaxis has to be improved. The duration of antibiotic prophylaxis was the main parameter of interest. Interventions have to be made about the development, distribution and adoption of adequate guidelines in collaboration with surgeons.

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Year:  2007        PMID: 17999981     DOI: 10.1093/jac/dkm406

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN: 0305-7453            Impact factor:   5.790


  40 in total

Review 1.  [Antibiotic prophylaxis and endoluminal tubes].

Authors:  C Justinger; M K Schilling
Journal:  Chirurg       Date:  2011-12       Impact factor: 0.955

2.  Improvement in Adherence to Surgical Antimicrobial Prophylaxis Guidelines after Implementation of a Multidisciplinary Quality Improvement Project.

Authors:  Shorouq Telfah; Lama Nazer; Manar Dirani; Faiez Daoud
Journal:  Sultan Qaboos Univ Med J       Date:  2015-11-23

3.  Adherence to guidelines for antibiotic prophylaxis in surgery patients in German hospitals: a multicentre evaluation involving pharmacy interns.

Authors:  C Hohmann; C Eickhoff; R Radziwill; M Schulz
Journal:  Infection       Date:  2011-10-15       Impact factor: 3.553

4.  Adherence to perioperative antibiotic prophylaxis among orthopedic trauma patients.

Authors:  Kristopher M Lundine; Susan Nelson; Richard Buckley; Sven Putnis; Paul J Duffy
Journal:  Can J Surg       Date:  2010-12       Impact factor: 2.089

5.  A Study on the Usage Pattern of Antimicrobial Agents for the Prevention of Surgical Site Infections (SSIs) in a Tertiary Care Teaching Hospital.

Authors:  Afzal Khan A K; Mirshad P V; Mohammed Rafiuddin Rashed; Gausia Banu
Journal:  J Clin Diagn Res       Date:  2013-02-27

6.  A Critical Evaluation and Comparison of Antimicrobial Prophylaxis in Elective Surgeries Across three Hospitals.

Authors:  Yogesh Belagali; Alwar Mc; Poornachandra Thejeswi; Ullal Sheetal D; Vani Bhagwath; Ashok Shenoy K; Mukta Chowta; Sahana D Acharya
Journal:  J Clin Diagn Res       Date:  2013-06-01

7.  Antimicrobial prescribing practices following publication of guidelines for the prevention of infections associated with combat-related injuries.

Authors:  David R Tribble; Bradley Lloyd; Amy Weintrob; Anuradha Ganesan; Clinton K Murray; Ping Li; William Bradley; Susan Fraser; Tyler Warkentien; Lakisha J Gaskins; Françoise Seillier-Moiseiwitsch; Eugene V Millar; Duane R Hospenthal
Journal:  J Trauma       Date:  2011-08

8.  Clinical pharmacists' review of surgical antimicrobial prophylaxis in a tertiary hospital in Abu Dhabi.

Authors:  Mohamed El Hassan; Asim Ahmed Elnour; Farah Hamad Farah; Abdulla Shehab; Naama M Al Kalbani; Sahar Asim; Omer Abdulla Shehab; Rauda Abdulla
Journal:  Int J Clin Pharm       Date:  2014-12-09

Review 9.  Antimicrobial Stewardship: A Call to Action for Surgeons.

Authors:  Massimo Sartelli; Therese M Duane; Fausto Catena; Jeffrey M Tessier; Federico Coccolini; Lillian S Kao; Belinda De Simone; Francesco M Labricciosa; Addison K May; Luca Ansaloni; John E Mazuski
Journal:  Surg Infect (Larchmt)       Date:  2016-11-09       Impact factor: 2.150

10.  Timing of surgical antibiotic prophylaxis administration: complexities of analysis.

Authors:  Carrie Cartmill; Lorelei Lingard; Glenn Regehr; Sherry Espin; John Bohnen; Ross Baker; Lorne Rotstein
Journal:  BMC Med Res Methodol       Date:  2009-06-23       Impact factor: 4.615

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