Spatial resolution measurement for iterative reconstruction by use of image-averaging techniques in computed tomography.

The purpose of our study was to investigate the validity of a spatial resolution measuring method that uses a combination of a bar-pattern phantom and an image-averaging technique, and to evaluate the spatial resolution property of iterative reconstruction (IR) images with middle-contrast (50 HU) objects. We used computed tomography (CT) images of the bar-pattern phantom reconstructed by the IR technology Adaptive Iterative Dose Reduction 3D (AIDR 3D), which was installed in the multidetector CT system Aquilion ONE (Toshiba Medical Systems, Otawara, Japan). The contrast of the bar-pattern image was set to 50 HU, which is considered to be a middle contrast that requires higher spatial resolution clinically. We employed an image-averaging technique to eliminate the influence of image noise, and we obtained averaged images of the bar-pattern phantom with sufficiently low noise. Modulation transfer functions (MTFs) were measured from the images. The conventional wire method was also used for comparison; in this method, AIDR 3D showed MTF values equivalent to those of filtered back projection. For the middle-contrast condition, the results showed that the MTF of AIDR 3D decreased with the strength of IR processing. Further, the MTF of AIDR 3D decreased with dose reduction. The image-averaging technique used was effective for correct evaluation of the spatial resolution for middle-contrast objects in IR images. The results obtained by our method clarified that the resolution preservation of AIDR 3D was not sufficient for middle-contrast objects.