| Literature DB >> 24130233 |
Yuni K Dewaraja1, Michael Ljungberg, Alan J Green, Pat B Zanzonico, Eric C Frey, Wesley E Bolch, A Bertrand Brill, Mark Dunphy, Darrell R Fisher, Roger W Howell, Ruby F Meredith, George Sgouros, Barry W Wessels.
Abstract
The reliability of radiation dose estimates in internal radionuclide therapy is directly related to the accuracy of activity estimates obtained at each imaging time point. The recently published MIRD pamphlet no. 23 provided a general overview of quantitative SPECT imaging for dosimetry. The present document is the first in a series of isotope-specific guidelines that will follow MIRD 23 and focuses on one of the most commonly used therapeutic radionuclides, (131)I. The purpose of this document is to provide guidance on the development of protocols for quantitative (131)I SPECT in radionuclide therapy applications that require regional (normal organs, lesions) and 3-dimensional dosimetry.Entities:
Keywords: 131I; MIRD; SPECT/CT, dosimetry; quantitative SPECT
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Year: 2013 PMID： 24130233 PMCID： PMC3970715 DOI： 10.2967/jnumed.113.122390
Source DB: PubMed Journal: J Nucl Med ISSN： 0161-5505 Impact factor: 10.057