Literature DB >> 24030287

Optimizing fracture prevention: the fracture liaison service, an observational study.

D A Eekman1, S H van Helden, A M Huisman, H J J Verhaar, I E M Bultink, P P Geusens, P Lips, W F Lems.   

Abstract

UNLABELLED: The response rate to the invitation to the fracture liaison service and reasons for non-response were evaluated in 2,207 fragility fracture patients. Fifty-one percent responded; non-responders were most often not interested (38 %) or were hip fracture patients. After 1 year of treatment, 88 % was still persistent and 2 % had a new fracture.
INTRODUCTION: To increase the percentage of elderly fracture patients undergoing a dual energy x-ray absorptiometry (DXA) measurement, and to investigate why some patients did not respond to invitation to our fracture liaison service (FLS).
METHODS: In four Dutch hospitals, fracture patients ≥ 50 years were invited through a written or personal invitation at the surgical outpatient department, for a DXA measurement and visit to our FLS. Patients who did not respond were contacted by telephone. In patients diagnosed with osteoporosis, treatment was started. Patients were contacted every 3 months during 1 year to assess drug persistence and the occurrence of subsequent fractures.
RESULTS: Of the 2,207 patients who were invited, 50.6 % responded. Most frequent reasons for not responding included: not interested (38 %), already screened/under treatment for osteoporosis (15.7 %), physically unable to attend the clinic (11.5 %), and death (5.2 %). Hip fracture patients responded less frequently (29 %) while patients with a wrist (60 %) or ankle fracture (65.2 %) were more likely to visit the clinic. In 337 responding patients, osteoporosis was diagnosed and treatment was initiated. After 12 months of follow-up, 88 % of the patients were still persistent with anti-osteoporosis therapy and only 2 % suffered a subsequent clinical fracture.
CONCLUSION: In elderly fracture patients, the use of a FLS leads to an increased response rate, a high persistence to drug treatment, and a low rate of subsequent clinical fractures. Additional programs for hip fracture patients are required, as these patients have a low response rate.

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Year:  2013        PMID: 24030287     DOI: 10.1007/s00198-013-2481-8

Source DB:  PubMed          Journal:  Osteoporos Int        ISSN: 0937-941X            Impact factor:   4.507


  35 in total

1.  Persistence and compliance of medications used in the treatment of osteoporosis--analysis using a large scale, representative, longitudinal German database.

Authors:  Volker Ziller; Karel Kostev; Ioannis Kyvernitakis; Jelena Boeckhoff; Peyman Hadji
Journal:  Int J Clin Pharmacol Ther       Date:  2012-05       Impact factor: 1.366

2.  Risk of new clinical fractures within 2 years following a fracture.

Authors:  Svenhjalmar van Helden; Jochen Cals; Fons Kessels; Peter Brink; Geert Jan Dinant; Piet Geusens
Journal:  Osteoporos Int       Date:  2005-12-24       Impact factor: 4.507

3.  Mortality after all major types of osteoporotic fracture in men and women: an observational study.

Authors:  J R Center; T V Nguyen; D Schneider; P N Sambrook; J A Eisman
Journal:  Lancet       Date:  1999-03-13       Impact factor: 79.321

4.  Management of osteoporosis in fracture liaison service associated with long-term adherence to treatment.

Authors:  L Boudou; B Gerbay; F Chopin; E Ollagnier; P Collet; T Thomas
Journal:  Osteoporos Int       Date:  2011-04-29       Impact factor: 4.507

Review 5.  Poor bisphosphonate adherence for treatment of osteoporosis increases fracture risk: systematic review and meta-analysis.

Authors:  I Imaz; P Zegarra; J González-Enríquez; B Rubio; R Alcazar; J M Amate
Journal:  Osteoporos Int       Date:  2009-12-05       Impact factor: 4.507

6.  The fracture and osteoporosis outpatient clinic: an effective strategy for improving implementation of an osteoporosis guideline.

Authors:  Svenhjalmar van Helden; Evelyne Cauberg; Piet Geusens; Bjorn Winkes; Trudy van der Weijden; Peter Brink
Journal:  J Eval Clin Pract       Date:  2007-10       Impact factor: 2.431

Review 7.  Efficacy of bisphosphonates in reducing fracture risk in postmenopausal osteoporosis.

Authors:  John P Bilezikian
Journal:  Am J Med       Date:  2009-02       Impact factor: 4.965

8.  Low-energy distal radius fractures in middle-aged and elderly men and women--the burden of osteoporosis and fracture risk : A study of 1794 consecutive patients.

Authors:  J Øyen; C G Gjesdal; C Brudvik; L M Hove; E M Apalset; H C Gulseth; G Haugeberg
Journal:  Osteoporos Int       Date:  2009-10-08       Impact factor: 4.507

9.  Prior fractures are common in patients with subsequent hip fractures.

Authors:  Beatrice J Edwards; Andrew D Bunta; Christine Simonelli; Mark Bolander; Lorraine A Fitzpatrick
Journal:  Clin Orthop Relat Res       Date:  2007-08       Impact factor: 4.176

10.  Osteoporotic fracture: missed opportunity for intervention.

Authors:  Leah Port; Jacqueline Center; N Kathy Briffa; Tuan Nguyen; Robert Cumming; John Eisman
Journal:  Osteoporos Int       Date:  2003-08-07       Impact factor: 4.507

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  26 in total

1.  Two-year adherence to treatment and associated factors in a fracture liaison service in Spain.

Authors:  A Naranjo; S Ojeda-Bruno; A Bilbao-Cantarero; J C Quevedo-Abeledo; B V Diaz-González; C Rodríguez-Lozano
Journal:  Osteoporos Int       Date:  2015-06-06       Impact factor: 4.507

2.  Secondary prevention of osteoporotic fractures: evaluation of the Amiens University Hospital's fracture liaison service between January 2010 and December 2011.

Authors:  N Dehamchia-Rehailia; D Ursu; I Henry-Desailly; P Fardellone; J Paccou
Journal:  Osteoporos Int       Date:  2014-07-01       Impact factor: 4.507

3.  Compliance and persistence to oral bisphosphonate therapy following initiation within a secondary fracture prevention program: a randomised controlled trial of specialist vs. non-specialist management.

Authors:  K Ganda; A Schaffer; S Pearson; M J Seibel
Journal:  Osteoporos Int       Date:  2014-01-21       Impact factor: 4.507

Review 4.  Critical issues and current challenges in osteoporosis and fracture prevention. An overview of unmet needs.

Authors:  Willem F Lems; Hennie G Raterman
Journal:  Ther Adv Musculoskelet Dis       Date:  2017-10-27       Impact factor: 5.346

5.  Challenges and opportunities to improve fracture liaison service attendance: fracture registration and patient characteristics and motivations.

Authors:  P van den Berg; P M M van Haard; P P Geusens; J P van den Bergh; D H Schweitzer
Journal:  Osteoporos Int       Date:  2019-05-25       Impact factor: 4.507

6.  [Osteological interdisciplinary management : exemplified by a bilateral proximal humeral fracture].

Authors:  C Neuerburg; K Pietschke; U Stumpf; S Sommerey; R Schmidmaier; B Ockert; W Böcker; F Haasters
Journal:  Unfallchirurg       Date:  2015-11       Impact factor: 1.000

7.  Meeting international standards of secondary fracture prevention: a survey on Fracture Liaison Services in the Netherlands.

Authors:  P van den Berg; D H Schweitzer; P M M van Haard; J P van den Bergh; P P Geusens
Journal:  Osteoporos Int       Date:  2015-04-10       Impact factor: 4.507

8.  Indirect costs account for half of the total costs of an osteoporotic fracture: a prospective evaluation.

Authors:  D A Eekman; M M ter Wee; V M H Coupé; S Erisek-Demirtas; M H Kramer; W F Lems
Journal:  Osteoporos Int       Date:  2013-09-27       Impact factor: 4.507

Review 9.  Fracture liaison services: promoting enhanced bone health care.

Authors:  Juliet Aizer; Marcy B Bolster
Journal:  Curr Rheumatol Rep       Date:  2014-11       Impact factor: 4.592

Review 10.  [Augmentation techniques on the proximal femur].

Authors:  C Neuerburg; M Gosch; M Blauth; W Böcker; C Kammerlander
Journal:  Unfallchirurg       Date:  2015-09       Impact factor: 1.000

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