PURPOSE: To evaluate the feasibility of prospectively guiding 4-dimensional (4D) magnetic resonance imaging (MRI) image acquisition using triggers at preselected respiratory amplitudes to achieve T(2) weighting for abdominal motion tracking. METHODS AND MATERIALS: A respiratory amplitude-based triggering system was developed and integrated into a commercial turbo spin echo MRI sequence. Initial feasibility tests were performed on healthy human study participants. Four respiratory states, the middle and the end of inhalation and exhalation, were used to trigger 4D MRI image acquisition of the liver. To achieve T(2) weighting, the echo time and repetition time were set to 75 milliseconds and 4108 milliseconds, respectively. Single-shot acquisition, together with parallel imaging and partial k-space imaging techniques, was used to improve image acquisition efficiency. 4D MRI image sets composed of axial or sagittal slices were acquired. RESULTS: Respiratory data measured and logged by the MRI scanner showed that the triggers occurred at the appropriate respiratory levels. Liver motion could be easily observed on both 4D MRI image datasets by sensing either the change of liver in size and shape (axial) or diaphragm motion (sagittal). Both 4D MRI image datasets were T(2)-weighted as expected. CONCLUSIONS: This study demonstrated the feasibility of achieving T(2)-weighted 4D MRI images using amplitude-based respiratory triggers. With the aid of the respiratory amplitude-based triggering system, the proposed method is compatible with most MRI sequences and therefore has the potential to improve tumor-tissue contrast in abdominal tumor motion imaging.
PURPOSE: To evaluate the feasibility of prospectively guiding 4-dimensional (4D) magnetic resonance imaging (MRI) image acquisition using triggers at preselected respiratory amplitudes to achieve T(2) weighting for abdominal motion tracking. METHODS AND MATERIALS: A respiratory amplitude-based triggering system was developed and integrated into a commercial turbo spin echo MRI sequence. Initial feasibility tests were performed on healthy human study participants. Four respiratory states, the middle and the end of inhalation and exhalation, were used to trigger 4D MRI image acquisition of the liver. To achieve T(2) weighting, the echo time and repetition time were set to 75 milliseconds and 4108 milliseconds, respectively. Single-shot acquisition, together with parallel imaging and partial k-space imaging techniques, was used to improve image acquisition efficiency. 4D MRI image sets composed of axial or sagittal slices were acquired. RESULTS: Respiratory data measured and logged by the MRI scanner showed that the triggers occurred at the appropriate respiratory levels. Liver motion could be easily observed on both 4D MRI image datasets by sensing either the change of liver in size and shape (axial) or diaphragm motion (sagittal). Both 4D MRI image datasets were T(2)-weighted as expected. CONCLUSIONS: This study demonstrated the feasibility of achieving T(2)-weighted 4D MRI images using amplitude-based respiratory triggers. With the aid of the respiratory amplitude-based triggering system, the proposed method is compatible with most MRI sequences and therefore has the potential to improve tumor-tissue contrast in abdominal tumor motion imaging.
Authors: J W Wong; M B Sharpe; D A Jaffray; V R Kini; J M Robertson; J S Stromberg; A A Martinez Journal: Int J Radiat Oncol Biol Phys Date: 1999-07-01 Impact factor: 7.038
Authors: P J Keall; G Starkschall; H Shukla; K M Forster; V Ortiz; C W Stevens; S S Vedam; R George; T Guerrero; R Mohan Journal: Phys Med Biol Date: 2004-05-21 Impact factor: 3.609
Authors: Juergen Biederer; Julien Dinkel; Gregor Remmert; Siri Jetter; Simeon Nill; Torsten Moser; Rolf Bendl; Carsten Thierfelder; Michael Fabel; Uwe Oelfke; Michael Bock; Christian Plathow; Hendrik Bolte; Thomas Welzel; Beata Hoffmann; Günter Hartmann; Wolfgang Schlegel; Jürgen Debus; Martin Heller; Hans-Ulrich Kauczor Journal: Int J Radiat Oncol Biol Phys Date: 2009-03-01 Impact factor: 7.038
Authors: Daniel A Low; Michelle Nystrom; Eugene Kalinin; Parag Parikh; James F Dempsey; Jeffrey D Bradley; Sasa Mutic; Sasha H Wahab; Tareque Islam; Gary Christensen; David G Politte; Bruce R Whiting Journal: Med Phys Date: 2003-06 Impact factor: 4.071
Authors: Dongsu Du; Shelton D Caruthers; Carri Glide-Hurst; Daniel A Low; H Harold Li; Sasa Mutic; Yanle Hu Journal: Int J Radiat Oncol Biol Phys Date: 2015-03-30 Impact factor: 7.038
Authors: Juan Yang; Jing Cai; Hongjun Wang; Zheng Chang; Brian G Czito; Mustafa R Bashir; Fang-Fang Yin Journal: Int J Radiat Oncol Biol Phys Date: 2014-01-17 Impact factor: 7.038
Authors: Guang Li; Jie Wei; Devin Olek; Mo Kadbi; Neelam Tyagi; Kristen Zakian; James Mechalakos; Joseph O Deasy; Margie Hunt Journal: Int J Radiat Oncol Biol Phys Date: 2016-11-09 Impact factor: 7.038