Literature DB >> 23247169

Drug discovery: nature's pieces.

Brian K Shoichet.   

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Year:  2013        PMID： 23247169     DOI： 10.1038/nchem.1537

Source DB:  PubMed          Journal:  Nat Chem        ISSN： 1755-4330            Impact factor:   24.427


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  12 in total

Review 1.  Current trends in lead discovery: are we looking for the appropriate properties?

Authors:  Tudor I Oprea
Journal:  Mol Divers       Date:  2002       Impact factor: 2.943

Review 2.  Natural products as sources of new drugs over the period 1981-2002.

Authors:  David J Newman; Gordon M Cragg; Kenneth M Snader
Journal:  J Nat Prod       Date:  2003-07       Impact factor: 4.050

Review 3.  Fragment-based lead discovery.

Authors:  David C Rees; Miles Congreve; Christopher W Murray; Robin Carr
Journal:  Nat Rev Drug Discov       Date:  2004-08       Impact factor: 84.694

Review 4.  Drugs for bad bugs: confronting the challenges of antibacterial discovery.

Authors:  David J Payne; Michael N Gwynn; David J Holmes; David L Pompliano
Journal:  Nat Rev Drug Discov       Date:  2006-12-08       Impact factor: 84.694

5.  Virtual exploration of the chemical universe up to 11 atoms of C, N, O, F: assembly of 26.4 million structures (110.9 million stereoisomers) and analysis for new ring systems, stereochemistry, physicochemical properties, compound classes, and drug discovery.

Authors:  Tobias Fink; Jean-Louis Reymond
Journal:  J Chem Inf Model       Date:  2007-01-30       Impact factor: 4.956

6.  Drug discovery: A question of library design.

Authors:  Philip J Hajduk; Warren R J D Galloway; David R Spring
Journal:  Nature       Date:  2011-02-03       Impact factor: 49.962

7.  Discovering high-affinity ligands for proteins: SAR by NMR.

Authors:  S B Shuker; P J Hajduk; R P Meadows; S W Fesik
Journal:  Science       Date:  1996-11-29       Impact factor: 47.728

Review 8.  The art and practice of structure-based drug design: a molecular modeling perspective.

Authors:  R S Bohacek; C McMartin; W C Guida
Journal:  Med Res Rev       Date:  1996-01       Impact factor: 12.944

9.  Natural-product-derived fragments for fragment-based ligand discovery.

Authors:  Björn Over; Stefan Wetzel; Christian Grütter; Yasushi Nakai; Steffen Renner; Daniel Rauh; Herbert Waldmann
Journal:  Nat Chem       Date:  2012-12-02       Impact factor: 24.427

10.  Quantifying biogenic bias in screening libraries.

Authors:  Jérôme Hert; John J Irwin; Christian Laggner; Michael J Keiser; Brian K Shoichet
Journal:  Nat Chem Biol       Date:  2009-05-31       Impact factor: 15.040
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  5 in total

1.  Estimation of the size of drug-like chemical space based on GDB-17 data.

Authors:  P G Polishchuk; T I Madzhidov; A Varnek
Journal:  J Comput Aided Mol Des       Date:  2013-08-21       Impact factor: 3.686

2.  Uncovering the potential of novel micromonosporae isolated from an extreme hyper-arid Atacama Desert soil.

Authors:  Lorena Carro; Jean Franco Castro; Valeria Razmilic; Imen Nouioui; Che Pan; José M Igual; Marcel Jaspars; Michael Goodfellow; Alan T Bull; Juan A Asenjo; Hans-Peter Klenk
Journal:  Sci Rep       Date:  2019-03-18       Impact factor: 4.379

3.  Identification and Heterologous Expression of the Chaxamycin Biosynthesis Gene Cluster from Streptomyces leeuwenhoekii.

Authors:  Jean Franco Castro; Valeria Razmilic; Juan Pablo Gomez-Escribano; Barbara Andrews; Juan A Asenjo; Mervyn J Bibb
Journal:  Appl Environ Microbiol       Date:  2015-06-19       Impact factor: 4.792

Review 4.  Capturing Biological Activity in Natural Product Fragments by Chemical Synthesis.

Authors:  Erika A Crane; Karl Gademann
Journal:  Angew Chem Int Ed Engl       Date:  2016-02-02       Impact factor: 15.336

5.  Metabolomic Diversity and Identification of Antibacterial Activities of Bacteria Isolated From Marine Sediments in Hawai'i and Puerto Rico.

Authors:  Ruhnaz Kashfi; Charles Kelsey; David Jorgen Gang; Douglas R Call; David R Gang
Journal:  Front Mol Biosci       Date:  2020-02-25
  5 in total

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