| Literature DB >> 23039167 |
Nils P Hailer1, Rüdiger J Weiss, André Stark, Johan Kärrholm.
Abstract
BACKGROUND ANDEntities:
Mesh:
Year: 2012 PMID: 23039167 PMCID: PMC3488169 DOI: 10.3109/17453674.2012.733919
Source DB: PubMed Journal: Acta Orthop ISSN: 1745-3674 Impact factor: 3.717
Age at index THA
| Age group | n | % |
|---|---|---|
| < 50 | 2,513 | 3 |
| 50–59 | 8,851 | 11 |
| 60–75 | 43,117 | 55 |
| > 75 | 23,617 | 30 |
Diagnosis at index THA
| Diagnosis | n | % |
|---|---|---|
| pOA | 64,987 | 83 |
| Fracture | 7,785 | 10 |
| FHN | 2,035 | 3 |
| Inflammatory | 1,486 | 2 |
| Pediatric | 1,249 | 2 |
| Other | 550 | 1 |
pOA: osteoarthritis;
FHN: femoral head necrosis;
a Missing data in 6 cases.
Head diameters inserted at index THA
| Diameter, mm | n | % |
|---|---|---|
| 22 | 1,394 | 2 |
| 28 | 57,194 | 73 |
| 32 | 16,451 | 21 |
| 36 | 2,772 | 4 |
| Dual-mobility | 287 | 0.4 |
Head size by diagnosis or by surgical approach
| 22 mm | 28 mm | 32 mm | 36 mm | Dual-mobility | |
|---|---|---|---|---|---|
|
| |||||
| pOA | 1,102 | 47,890 | 13,717 | 2,210 | 68 |
| Inflammatory | 28 | 1,144 | 226 | 85 | 3 |
| Fracture | 146 | 5,530 | 1,764 | 171 | 174 |
| Pediatric | 64 | 845 | 142 | 188 | 10 |
| FHN | 46 | 1,387 | 469 | 109 | 24 |
| Other | 8 | 392 | 133 | 9 | 8 |
|
| |||||
| Direct lateral | 1,191 | 25,696 | 6,929 | 1,450 | 194 |
| Posterior | 1,92 | 30,856 | 9,464 | 1,299 | 93 |
| MIS | 11 | 642 | 58 | 23 | 0 |
pOA: osteoarthritis;
FHN: femoral head necrosis;
MIS: minimally invasive approaches.
Cup types inserted during index THA
| Cup type | n | % |
|---|---|---|
| Lubinus | 33,754 | 43 |
| Hooded Duration | 7,802 | 10 |
| Charnley Elite | 7,165 | 9 |
| ZCA | 6,854 | 9 |
| Trilogy | 4,167 | 5 |
| Exeter Duration | 4,088 | 5 |
| Marathon | 3,102 | 4 |
| FAL | 2,947 | 4 |
| Reflection | 2,241 | 3 |
| Trident HA | 1,705 | 2 |
| Reflection XLPE | 1,601 | 2 |
| Charnley | 1,265 | 2 |
| Allofit | 1,120 | 1 |
| Avantage | 287 | 0.3 |
Figure 1.Frequency of revision surgery due to dislocation plotted against time elapsed after the index procedure.
Cox regression analysis of risk factors for revision due to dislocation a
| Unadjusted | Adjusted | p-value | |||
|---|---|---|---|---|---|
| RR | 95% CI | RR | 95% CI | ||
| Head diameter | |||||
| 28 mm | 1 | 1 | |||
| 22 mm | 1.8 | (1.1–2.9) | 2.0 | (1.2–3.3) | 0.01 |
| 32 mm | 0.8 | (0.6–1.1) | 0.8 | (0.6–1.1) | 0.1 |
| 36 mm | 0.7 | (0.3–1.3) | 0.7 | (0.3–1.4) | 0.3 |
| Dual-mobility | 0.9 | (0.1–6.1) | 0.4 | (0.1–2.9) | 0.4 |
| Sex | |||||
| Female | 0.9 | (0.8–1.1) | 0.8 | (0.7–1.0) | 0.03 |
| Diagnosis | |||||
| pOA | 1 | 1 | |||
| Inflammatory | 1.0 | (0.5–2.3) | 1.0 | (0.4–2.3) | 1.0 |
| Fracture | 3.7 | (2.9–4.7) | 3.9 | (3.1–5.0) | < 0.001 |
| Pediatric | 1.5 | (0.7–3.1) | 1.5 | (0.7–3.2) | 0.3 |
| FHN | 3.6 | (2.4–5.4) | 3.7 | (2.5–5.5) | < 0.001 |
| Other | 5.4 | (2.7–10.9) | 5.6 | (2.8–11.4) | < 0.001 |
| Age | |||||
| < 50 | 1 | 1 | |||
| 50–59 | 0.9 | (0.5–1.7) | 1.1 | (0.6–2.0) | 0.8 |
| 60–75 | 0.8 | (0.5–1.4) | 0.9 | (0.5–1.6) | 0.7 |
| > 75 | 1.2 | (0.7–2.0) | 1.1 | (0.6–2.0) | 0.6 |
| Approach | |||||
| Direct lateral | 1 | 1 | |||
| Posterior | 1.2 | (1.0–1.4) | 1.3 | (1.1–1.7) | 0.01 |
| MIS | 3.3 | (1.8–5.9) | 4.2 | (2.3–7.7) | < 0.001 |
Unadjusted and adjusted risk ratios (RRs) were calculated with 95% CI using a Cox proportional hazards model. p values refer to adjusted RR.
Reference category with RR = 1.
Reference category was male with RR = 1.
Abbreviations, see Table 4.
Figure 2.Survival functions with the endpoint “revision due to dislocation” by surgical approach. A Cox proportional hazards model was used in order to calculate adjusted survival functions with 95% CI (dotted lines) for the 3 surgical approaches lateral (n = 35,460), posterior (n = 41,904), and minimally invasive (n = 734). The endpoint was revision due to dislocation. Survival functions were adjusted for the mean of the covariates gender, age, primary diagnosis, and femoral head size. The lateral approach was associated with the lowest risk of revision due to dislocation.
Figure 3.Survival functions for patients with a femoral neck fracture with the endpoint “revision due to dislocation” by femoral head size. A Cox proportional hazards model was used to calculate adjusted survival functions with 95% CI (dotted lines) for patients with a femoral head fracture, for the femoral head sizes 22 mm (n = 1,394) and 28 mm (n = 57,194), and dual-mobility cups (n = 287). The endpoint was revision due to dislocation. Survival functions were adjusted for the mean of the covariates gender, age, and surgical approach but fixed for the diagnosis femoral neck fracture. Dual-mobility cups were associated with the lowest risk of revision due to dislocation.