Literature DB >> 23024624

Cervical radiculopathy: a review.

John M Caridi1, Matthias Pumberger, Alexander P Hughes.   

Abstract

BACKGROUND: Cervical radiculopathy is defined as a syndrome of pain and/or sensorimotor deficits due to compression of a cervical nerve root. Understanding of this disease is vital for rapid diagnosis and treatment of patients with this condition, facilitating their recovery and return to regular activity.
PURPOSE: This review is designed to clarify (1) the pathophysiology that leads to nerve root compression; (2) the diagnosis of the disease guided by history, physical exam, imaging, and electrophysiology; and (3) operative and non-operative options for treatment and how these should be applied.
METHODS: The PubMed database was searched for relevant articles and these articles were reviewed by independent authors. The conclusions are presented in this manuscript.
RESULTS: Facet joint spondylosis and herniation of the intervertebral disc are the most common causes of nerve root compression. The clinical consequence of radiculopathy is arm pain or paresthesias in the dermatomal distribution of the affected nerve and may or may not be associated with neck pain and motor weakness. Patient history and clinical examination are important for diagnosis. Further imaging modalities, such as x-ray, computed tomography, magnetic resonance imaging, and electrophysiologic testing, are of importance. Most patients will significantly improve from non-surgical active and passive therapies. Indicated for surgery are patients with clinically significant motor deficits, debilitating pain that is resistant to conservative modalities and/or time, or instability in the setting of disabling radiculopathy. Surgical treatment options include anterior cervical decompression with fusion and posterior cervical laminoforaminotomy.
CONCLUSION: Understanding the pathophysiology, diagnosis, treatment indications, and treatment techniques is essential for rapid diagnosis and care of patients with cervical radiculopathy.

Entities:  

Keywords:  ACDF; ADF; cervical radiculopathy; disc herniation; posterior cervical foraminotomy; posterior cervical laminoforaminotomy

Year:  2011        PMID: 23024624      PMCID: PMC3192889          DOI: 10.1007/s11420-011-9218-z

Source DB:  PubMed          Journal:  HSS J        ISSN: 1556-3316


  72 in total

Review 1.  Complications of cervical transforaminal epidural steroid injections.

Authors:  Benoy Benny; Pari Azari; Dean Briones
Journal:  Am J Phys Med Rehabil       Date:  2010-07       Impact factor: 2.159

2.  Clinical trial of a cervical traction modality with electromyographic biofeedback.

Authors:  A M Wong; M Y Lee; W H Chang; F T Tang
Journal:  Am J Phys Med Rehabil       Date:  1997 Jan-Feb       Impact factor: 2.159

Review 3.  Management of cervical radiculopathy.

Authors:  J van Gijn; K Reiners; K V Toyka; R Braakman
Journal:  Eur Neurol       Date:  1995       Impact factor: 1.710

4.  The pathomorphologic changes that accompany the resolution of cervical radiculopathy. A prospective study with repeat magnetic resonance imaging.

Authors:  K Bush; R Chaudhuri; S Hillier; J Penny
Journal:  Spine (Phila Pa 1976)       Date:  1997-01-15       Impact factor: 3.468

5.  Epidemiology of cervical radiculopathy. A population-based study from Rochester, Minnesota, 1976 through 1990.

Authors:  K Radhakrishnan; W J Litchy; W M O'Fallon; L T Kurland
Journal:  Brain       Date:  1994-04       Impact factor: 13.501

6.  Cervical laminoforaminotomy for the treatment of cervical degenerative radiculopathy.

Authors:  Robert F Heary; Timothy C Ryken; Paul G Matz; Paul A Anderson; Michael W Groff; Langston T Holly; Michael G Kaiser; Praveen V Mummaneni; Tanvir F Choudhri; Edward J Vresilovic; Daniel K Resnick
Journal:  J Neurosurg Spine       Date:  2009-08

7.  The efficacy of the synthetic interbody cage and Grafton for anterior cervical fusion.

Authors:  Hyun-Woong Park; Jung-Kil Lee; Sung-Jun Moon; Seung-Kweon Seo; Jae-Hyun Lee; Soo-Han Kim
Journal:  Spine (Phila Pa 1976)       Date:  2009-08-01       Impact factor: 3.468

8.  Prospective nonrandomized comparison of an allograft with bone morphogenic protein versus an iliac-crest autograft in anterior cervical discectomy and fusion.

Authors:  Glenn Robin Buttermann
Journal:  Spine J       Date:  2007-03-07       Impact factor: 4.166

9.  Does rigid instrumentation increase the fusion rate in one-level anterior cervical discectomy and fusion?

Authors:  Dino Samartzis; Francis H Shen; Craig Lyon; Mathew Phillips; Edward J Goldberg; Howard S An
Journal:  Spine J       Date:  2004 Nov-Dec       Impact factor: 4.166

10.  Cervical interlaminar epidural steroid injection for neck pain and cervical radiculopathy: effect and prognostic factors.

Authors:  Jong Won Kwon; Joon Woo Lee; Sung Hyun Kim; Ja-Young Choi; Jin-Sup Yeom; Hyun-Jib Kim; Kyu-Sung Kwack; Sung Gyu Moon; Woo Sun Jun; Heung Sik Kang
Journal:  Skeletal Radiol       Date:  2007-03-06       Impact factor: 2.199

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  47 in total

1.  Cervical cages placed bilaterally in the facet joints from a posterior approach significantly increase foraminal area.

Authors:  Kris Siemionow; Piotr Janusz; Pawel Glowka
Journal:  Eur Spine J       Date:  2016-02-11       Impact factor: 3.134

Review 2.  Systematic review of radiological cervical foraminal grading systems.

Authors:  James Meacock; Moritz Schramm; Senthil Selvanathan; Stuart Currie; Deborah Stocken; David Jayne; Simon Thomson
Journal:  Neuroradiology       Date:  2021-01-04       Impact factor: 2.804

3.  Successful outcomes following transforaminal epidural steroid injections for C4/5 cervical disc prolapse associated with profound neurological deficit.

Authors:  Adam Meir; Keith Bush
Journal:  Eur Spine J       Date:  2017-03-27       Impact factor: 3.134

4.  Classification by pain pattern for patients with cervical spine radiculopathy.

Authors:  Richard Yarznbowicz; Matt Wlodarski; Jonathan Dolutan
Journal:  J Man Manip Ther       Date:  2019-05-02

5.  CERVICAL CONTRIBUTION TO FUNCTIONAL SHOULDER IMPINGEMENT: TWO CASE REPORTS.

Authors:  Steven Pheasant
Journal:  Int J Sports Phys Ther       Date:  2016-12

Review 6.  Spinal Injuries in the Overhead Athlete.

Authors:  Robert G Watkins; David Chang; Robert G Watkins
Journal:  Curr Rev Musculoskelet Med       Date:  2022-09-29

7.  Pre-treatment with Meloxicam Prevents the Spinal Inflammation and Oxidative Stress in DRG Neurons that Accompany Painful Cervical Radiculopathy.

Authors:  Sonia Kartha; Christine L Weisshaar; Blythe H Philips; Beth A Winkelstein
Journal:  Neuroscience       Date:  2018-08-04       Impact factor: 3.590

Review 8.  Cervical radiculopathy.

Authors:  Sravisht Iyer; Han Jo Kim
Journal:  Curr Rev Musculoskelet Med       Date:  2016-09

9.  The impact of preoperative motor weakness on postoperative opioid use after ACDF.

Authors:  Hannah A Levy; Brian A Karamian; Jeffrey Henstenburg; Joseph Larwa; Jose A Canseco; Brett Haislup; Michael Chang; Parthik Patel; Kris E Radcliff; Barrett I Woods; Mark F Kurd; Alan S Hilibrand; Christopher K Kepler; Alexander R Vaccaro; Gregory D Schroeder
Journal:  J Orthop       Date:  2021-06-30

10.  Diagnostic Implication and Clinical Relevance of Dermatomal Somatosensory Evoked Potentials in Patients with Radiculopathy: A Retrospective Study.

Authors:  Nam-Gyu Jo; Myoung-Hwan Ko; Yu Hui Won; Sung-Hee Park; Gi-Wook Kim; Jeong-Hwan Seo
Journal:  Pain Res Manag       Date:  2021-06-01       Impact factor: 3.037

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