| Literature DB >> 34276147 |
Hannah A Levy1, Brian A Karamian1, Jeffrey Henstenburg1, Joseph Larwa1, Jose A Canseco1, Brett Haislup1, Michael Chang1, Parthik Patel1, Kris E Radcliff1, Barrett I Woods1, Mark F Kurd1, Alan S Hilibrand1, Christopher K Kepler1, Alexander R Vaccaro1, Gregory D Schroeder1.
Abstract
This study aims to determine if preoperative weakness is an isolated risk factor for prolonged postoperative opioid use after anterior cervical discectomy and fusion (ACDF). Patients with preoperative weakness were significantly more likely to have prolonged and inappropriate opioid use and have a single prescription mean morphine equivalent (MME) ≥ 200. Logistic regression isolated preoperative weakness, opioid tolerance, depression, and VAS Neck pain as independent predictors of extended opioid use. High postoperative opioid dose (MME ≥ 90) correlated with opioid tolerance, younger age, male sex, greater CCI, prior cervical surgery, and preoperative VAS Neck pain on regression.Entities:
Keywords: ACDF; Charlson comorbidity index, CCI; Motor weakness; Narcotics; Opioid; Pennsylvania prescription drug monitoring program, PDMP; Risk factors; Spine surgery; anterior cervical discectomy and fusion, ACDF; body mass index, BMI; health-related quality of life, HRQOL; manual muscle testing, MMT; mean morphine equivalent, MME; odds ratio, OR; visual analogue scale, VAS
Year: 2021 PMID： 34276147 PMCID： PMC8267480 DOI： 10.1016/j.jor.2021.06.003
Source DB: PubMed Journal: J Orthop ISSN： 0972-978X