Literature DB >> 22810693

Chemical biology: Greasy tags for protein removal.

Taavi K Neklesa, Craig M Crews.   

Abstract

Mesh：

Year:  2012        PMID： 22810693     DOI： 10.1038/487308a

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


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  7 in total

1.  Identification of hydrophobic tags for the degradation of stabilized proteins.

Authors:  Hyun Seop Tae; Thomas B Sundberg; Taavi K Neklesa; Devin J Noblin; Jeffrey L Gustafson; Anke G Roth; Kanak Raina; Craig M Crews
Journal:  Chembiochem       Date:  2012-01-23       Impact factor: 3.164

2.  The druggable genome: an update.

Authors:  Andreas P Russ; Stefan Lampel
Journal:  Drug Discov Today       Date:  2005-12       Impact factor: 7.851

3.  Design, synthesis and selection of DNA-encoded small-molecule libraries.

Authors:  Matthew A Clark; Raksha A Acharya; Christopher C Arico-Muendel; Svetlana L Belyanskaya; Dennis R Benjamin; Neil R Carlson; Paolo A Centrella; Cynthia H Chiu; Steffen P Creaser; John W Cuozzo; Christopher P Davie; Yun Ding; G Joseph Franklin; Kurt D Franzen; Malcolm L Gefter; Steven P Hale; Nils J V Hansen; David I Israel; Jinwei Jiang; Malcolm J Kavarana; Michael S Kelley; Christopher S Kollmann; Fan Li; Kenneth Lind; Sibongile Mataruse; Patricia F Medeiros; Jeffrey A Messer; Paul Myers; Heather O'Keefe; Matthew C Oliff; Cecil E Rise; Alexander L Satz; Steven R Skinner; Jennifer L Svendsen; Lujia Tang; Kurt van Vloten; Richard W Wagner; Gang Yao; Baoguang Zhao; Barry A Morgan
Journal:  Nat Chem Biol       Date:  2009-08-02       Impact factor: 15.040

Review 4.  Small-molecule discovery from DNA-encoded chemical libraries.

Authors:  Ralph E Kleiner; Christoph E Dumelin; David R Liu
Journal:  Chem Soc Rev       Date:  2011-06-14       Impact factor: 54.564

5.  Inhibitor mediated protein degradation.

Authors:  Marcus J C Long; Deviprasad R Gollapalli; Lizbeth Hedstrom
Journal:  Chem Biol       Date:  2012-05-25

6.  Chemical genetic control of protein levels: selective in vivo targeted degradation.

Authors:  John S Schneekloth; Fabiana N Fonseca; Michael Koldobskiy; Amit Mandal; Raymond Deshaies; Kathleen Sakamoto; Craig M Crews
Journal:  J Am Chem Soc       Date:  2004-03-31       Impact factor: 15.419

7.  Small-molecule hydrophobic tagging-induced degradation of HaloTag fusion proteins.

Authors:  Taavi K Neklesa; Hyun Seop Tae; Ashley R Schneekloth; Michael J Stulberg; Timothy W Corson; Thomas B Sundberg; Kanak Raina; Scott A Holley; Craig M Crews
Journal:  Nat Chem Biol       Date:  2011-07-03       Impact factor: 15.040
  7 in total
  25 in total

Review 1.  Preclinical and Clinical Advances of Targeted Protein Degradation as a Novel Cancer Therapeutic Strategy: An Oncologist Perspective.

Authors:  Xinrui Yang; He Yin; Richard D Kim; Jason B Fleming; Hao Xie
Journal:  Target Oncol       Date:  2020-12-28       Impact factor: 4.493

2.  Know your target, know your molecule.

Authors:  Mark E Bunnage; Adam M Gilbert; Lyn H Jones; Erik C Hett
Journal:  Nat Chem Biol       Date:  2015-06       Impact factor: 15.040

3.  Association between foldability and aggregation propensity in small disulfide-rich proteins.

Authors:  Hugo Fraga; Ricardo Graña-Montes; Ricard Illa; Giovanni Covaleda; Salvador Ventura
Journal:  Antioxid Redox Signal       Date:  2014-05-05       Impact factor: 8.401

4.  The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study.

Authors:  George M Burslem; Blake E Smith; Ashton C Lai; Saul Jaime-Figueroa; Daniel C McQuaid; Daniel P Bondeson; Momar Toure; Hanqing Dong; Yimin Qian; Jing Wang; Andrew P Crew; John Hines; Craig M Crews
Journal:  Cell Chem Biol       Date:  2017-11-09       Impact factor: 8.116

5.  Boc3Arg-Linked Ligands Induce Degradation by Localizing Target Proteins to the 20S Proteasome.

Authors:  Yuntao Shi; Marcus J C Long; Masha M Rosenberg; Shican Li; Aimee Kobjack; Philip Lessans; Rory T Coffey; Lizbeth Hedstrom
Journal:  ACS Chem Biol       Date:  2016-10-18       Impact factor: 5.100

Review 6.  Emerging modes-of-action in drug discovery.

Authors:  Eric Valeur; Frank Narjes; Christian Ottmann; Alleyn T Plowright
Journal:  Medchemcomm       Date:  2019-06-25       Impact factor: 3.597

Review 7.  Induced protein degradation: an emerging drug discovery paradigm.

Authors:  Ashton C Lai; Craig M Crews
Journal:  Nat Rev Drug Discov       Date:  2016-11-25       Impact factor: 84.694

8.  Discovery of a first-in-class EZH2 selective degrader.

Authors:  Anqi Ma; Elias Stratikopoulos; Kwang-Su Park; Jieli Wei; Tiphaine C Martin; Xiaobao Yang; Megan Schwarz; Violetta Leshchenko; Alexander Rialdi; Brandon Dale; Alessandro Lagana; Ernesto Guccione; Samir Parekh; Ramon Parsons; Jian Jin
Journal:  Nat Chem Biol       Date:  2019-12-09       Impact factor: 15.040

Review 9.  Targeted Protein Degradation: from Chemical Biology to Drug Discovery.

Authors:  Philipp M Cromm; Craig M Crews
Journal:  Cell Chem Biol       Date:  2017-06-22       Impact factor: 8.116

10.  Degradation of Akt using protein-catalyzed capture agents.

Authors:  Ryan K Henning; Joseph O Varghese; Samir Das; Arundhati Nag; Grace Tang; Kevin Tang; Alexander M Sutherland; James R Heath
Journal:  J Pept Sci       Date:  2016-02-16       Impact factor: 1.905
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