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Literature DB >> 22006680

DNA nanotechnology for nucleic acid analysis: DX motif-based sensor.

Dmitry M Kolpashchikov¹, Yulia V Gerasimova, Mohammad S Khan.

Abstract

A light on the tiles: A sensor that fluoresces in the presence of specific nucleic acids was designed and characterized. The sensor uses a molecular beacon probe and three adaptor strands to form a five-stranded assembly, a DX-tile, with a specific analyte. This sensor is a highly selective and affordable tool for the real-time analysis of DNA and RNA.

Entities: CellLine Chemical Gene Mutation Species

Mesh：

Substances：
Molecular Probes
RNA
DNA

Year: 2011 PMID： 22006680 PMCID： PMC3221779 DOI： 10.1002/cbic.201100545

Source DB: PubMed Journal: Chembiochem ISSN： 1439-4227 Impact factor: 3.164

32 in total

1. Molecular-beacon-based tricomponent probe for SNP analysis in folded nucleic acids.

Authors: Camha Nguyen; Jeffrey Grimes; Yulia V Gerasimova; Dmitry M Kolpashchikov
Journal: Chemistry Date: 2011-09-28 Impact factor: 5.236

Review 2. Molecular typing methodologies for microbial source tracking and epidemiological investigations of Gram-negative bacterial foodborne pathogens.

Authors: Steven L Foley; Aaron M Lynne; Rajesh Nayak
Journal: Infect Genet Evol Date: 2009-03-24 Impact factor: 3.342

3. Intrinsic DNA curvature of double-crossover tiles.

Authors: Seungjae Kim; Junghoon Kim; Pengfei Qian; Jihoon Shin; Rashid Amin; Sang Jung Ahn; Thomas H LaBean; Moon Ki Kim; Sung Ha Park
Journal: Nanotechnology Date: 2011-05-04 Impact factor: 3.874

Review 4. Nucleic acid based molecular devices.

Authors: Yamuna Krishnan; Friedrich C Simmel
Journal: Angew Chem Int Ed Engl Date: 2011-03-28 Impact factor: 15.336

Review 5. Nanomaterials based on DNA.

Authors: Nadrian C Seeman
Journal: Annu Rev Biochem Date: 2010 Impact factor: 23.643

DNA nanotechnology for nucleic acid analysis: DX motif-based sensor.

1. Molecular-beacon-based tricomponent probe for SNP analysis in folded nucleic acids.

Review 2. Molecular typing methodologies for microbial source tracking and epidemiological investigations of Gram-negative bacterial foodborne pathogens.

3. Intrinsic DNA curvature of double-crossover tiles.

Review 4. Nucleic acid based molecular devices.

Review 5. Nanomaterials based on DNA.

6. Enzyme-assisted binary probe for sensitive detection of RNA and DNA.

7. Real-time SNP analysis in secondary-structure-folded nucleic acids.

8. A single molecular beacon probe is sufficient for the analysis of multiple nucleic acid sequences.

9. An optimized microarray platform for assaying genomic variation in Plasmodium falciparum field populations.

10. Dynamic patterning programmed by DNA tiles captured on a DNA origami substrate.

1. A differential fluorescent receptor for nucleic acid analysis.

2. Detection of bacterial 16S rRNA using a molecular beacon-based X sensor.

3. DNA nanotechnology for nucleic acid analysis: multifunctional molecular DNA machine for RNA detection.

4. DNA Antenna Tile-Associated Deoxyribozyme Sensor with Improved Sensitivity.

5. Divide and Control: Comparison of Split and Switch Hybridization Sensors.

6. Molecular logic gates for DNA analysis: detection of rifampin resistance in M. tuberculosis DNA.

7. Nonequilibrium Hybridization Enables Discrimination of a Point Mutation within 5-40 °C.

8. Operating Cooperatively (OC) sensor for highly specific recognition of nucleic acids.

9. Integrating DNA strand-displacement circuitry with DNA tile self-assembly.

Review 10. An elegant biosensor molecular beacon probe: challenges and recent solutions.