Literature DB >> 21933782

Fish oil and omega-3 fatty acids in cardiovascular disease: do they really work?

Daan Kromhout1, Satoshi Yasuda, Johanna M Geleijnse, Hiroaki Shimokawa.   

Abstract

Omega-3 fatty acids, which are found abundantly in fish oil, exert pleiotropic cardiometabolic effects with a diverse range of actions. The results of previous studies raised a lot of interest in the role of fish oil and omega-3 fatty acids in primary and secondary prevention of cardiovascular diseases. The present review will focus on the current clinical uses of omega-3 fatty acids and provide an update on their effects. Since recently published trials in patients with coronary artery diseases or post-myocardial infarction did not show an effect of omega-3 fatty acids on major cardiovascular endpoints, this review will examine the limitations of those data and suggest recommendations for the use of omega-3 fatty acids.

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Year:  2011        PMID： 21933782      PMCID： PMC3279313          DOI： 10.1093/eurheartj/ehr362

Source DB:  PubMed          Journal:  Eur Heart J        ISSN： 0195-668X            Impact factor:   29.983


  66 in total

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Authors:  H M SINCLAIR
Journal:  Lancet       Date:  1956-04-07       Impact factor: 79.321

2.  Meta-analysis of observational studies on fish intake and coronary heart disease.

Authors:  Seamus Paul Whelton; Jiang He; Paul Kieran Whelton; Paul Muntner
Journal:  Am J Cardiol       Date:  2004-05-01       Impact factor: 2.778

3.  Eicosapentaenoic acid reduces ischemic ventricular fibrillation via altering monophasic action potential in pigs.

Authors:  Ryuji Tsuburaya; Satoshi Yasuda; Yoshitaka Ito; Takashi Shiroto; Jun Yi Gao; Kenta Ito; Hiroaki Shimokawa
Journal:  J Mol Cell Cardiol       Date:  2011-05-30       Impact factor: 5.000

Review 4.  Fish consumption and coronary heart disease mortality. A systematic review of prospective cohort studies.

Authors:  P Marckmann; M Grønbaek
Journal:  Eur J Clin Nutr       Date:  1999-08       Impact factor: 4.016

5.  Beneficial effect of hydroxyfasudil, a specific Rho-kinase inhibitor, on ischemia/reperfusion injury in canine coronary microcirculation in vivo.

Authors:  Toyotaka Yada; Hiroaki Shimokawa; Osamu Hiramatsu; Tatsuya Kajita; Fumiyuki Shigeto; Etsuro Tanaka; Yoshiro Shinozaki; Hidezo Mori; Takahiko Kiyooka; Masashi Katsura; Seitaro Ohkuma; Masami Goto; Yasuo Ogasawara; Fumihiko Kajiya
Journal:  J Am Coll Cardiol       Date:  2005-02-15       Impact factor: 24.094

6.  Fish and omega-3 fatty acid intake and risk of coronary heart disease in women.

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Journal:  JAMA       Date:  2002-04-10       Impact factor: 56.272

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Journal:  Blood       Date:  1993-04-01       Impact factor: 22.113

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Authors:  H Hallaq; T W Smith; A Leaf
Journal:  Proc Natl Acad Sci U S A       Date:  1992-03-01       Impact factor: 11.205

Review 9.  omega-3 polyunsaturated fatty acid supplementation for the treatment of heart failure: mechanisms and clinical potential.

Authors:  Monika K Duda; Karen M O'Shea; William C Stanley
Journal:  Cardiovasc Res       Date:  2009-05-27       Impact factor: 10.787

10.  Remnant lipoproteins from patients with sudden cardiac death enhance coronary vasospastic activity through upregulation of Rho-kinase.

Authors:  Keiji Oi; Hiroaki Shimokawa; Junko Hiroki; Toyokazu Uwatoku; Kohtaro Abe; Yasuharu Matsumoto; Yasuhiro Nakajima; Katsuyuki Nakajima; Sanae Takeichi; Akira Takeshita
Journal:  Arterioscler Thromb Vasc Biol       Date:  2004-03-25       Impact factor: 8.311
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  60 in total

1.  Effects of n-3 fatty acids on major cardiovascular events in statin users and non-users with a history of myocardial infarction.

Authors:  Simone R B M Eussen; Johanna M Geleijnse; Erik J Giltay; Cathy J M Rompelberg; Olaf H Klungel; Daan Kromhout
Journal:  Eur Heart J       Date:  2012-02-01       Impact factor: 29.983

Review 2.  Metabolic/inflammatory/vascular comorbidity in psychiatric disorders; soluble epoxide hydrolase (sEH) as a possible new target.

Authors:  W Swardfager; M Hennebelle; D Yu; B D Hammock; A J Levitt; K Hashimoto; A Y Taha
Journal:  Neurosci Biobehav Rev       Date:  2018-02-02       Impact factor: 8.989

3.  Prevalence of Glucosamine and Omega-3 Fatty Acid Use and Characteristics of Users among Mid-Age Women: Analysis of a Nationally Representative Sample of 10,638 Women.

Authors:  D Sibbritt; C Lui; T Kroll; J Adams
Journal:  J Nutr Health Aging       Date:  2016       Impact factor: 4.075

Review 4.  Omega-3 in antiarrhythmic therapy : pros position.

Authors:  Bruno Trimarco
Journal:  High Blood Press Cardiovasc Prev       Date:  2013-02-19

5.  The association between marine n-3 polyunsaturated fatty acid levels and survival after renal transplantation.

Authors:  Ivar A Eide; Trond Jenssen; Anders Hartmann; Lien M Diep; Dag O Dahle; Anna V Reisæter; Kristian S Bjerve; Jeppe H Christensen; Erik B Schmidt; My Svensson
Journal:  Clin J Am Soc Nephrol       Date:  2015-06-10       Impact factor: 8.237

6.  Fish intake or omega-3 fatty acids: greater than the sum of all parts?

Authors:  Jessica C Kiefte-de Jong; Rajiv Chowdhury; Oscar H Franco
Journal:  Eur J Epidemiol       Date:  2013-01-03       Impact factor: 8.082

7.  Diet and cardiovascular disease.

Authors:  W M Monique Verschuren
Journal:  Curr Cardiol Rep       Date:  2012-12       Impact factor: 2.931

8.  Double-blind randomized placebo-controlled clinical trial of omega 3 fatty acids for the treatment of diabetic patients with nonalcoholic steatohepatitis.

Authors:  Srinivasan Dasarathy; Jaividhya Dasarathy; Amer Khiyami; Lisa Yerian; Carol Hawkins; Ruth Sargent; Arthur J McCullough
Journal:  J Clin Gastroenterol       Date:  2015-02       Impact factor: 3.062

9.  Omega-3 fatty acids: An update emphasizing clinical use.

Authors:  David Kiefer; Traci Pantuso
Journal:  Agro Food Ind Hi Tech       Date:  2012-07

10.  Omega-3 fatty acids lower blood pressure by directly activating large-conductance Ca²⁺-dependent K⁺ channels.

Authors:  Toshinori Hoshi; Bianka Wissuwa; Yutao Tian; Nobuyoshi Tajima; Rong Xu; Michael Bauer; Stefan H Heinemann; Shangwei Hou
Journal:  Proc Natl Acad Sci U S A       Date:  2013-03-04       Impact factor: 11.205
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