OBJECTIVE: To compare quantitatively and qualitatively hepatocyte-phase images obtained 10 and 20 min (Images-10, and Images-20) after injection of gadolinium-ethoxybenzyl-diethylenetriamine-pentaacetic acid (Gd-EOB-DTPA) to detect liver metastases from colorectal carcinoma on 3.0 T MR imaging. METHODS: A total of 48 patients (26 men, 22 women; mean age, 64 years) with 88 histopathologically confirmed liver metastases underwent Gd-EOB-DTPA-enhanced MR imaging. Tumour-to-liver contrast-to-noise ratio (CNR), signal intensity gain (SIG) of liver parenchyma and overall image quality were analysed. Two radiologists independently reviewed two sets of MR images: set 1, unenhanced (T1- and T2-weighted), dynamic images and Images-10; set 2, unenhanced, dynamic and Images-20. Sensitivity and positive predictive value (PPV) to detect liver metastases, and diagnostic performance using the alternative free-response receiver operating characteristics (AFROC) method were calculated. RESULTS: The mean tumour-to-liver CNR, SIG of liver parenchyma and overall image quality on Images-20 were significantly higher than those on Images-10. The overall image quality of "fair to excellent" was achieved on both images in 93.8% of the patients. Sensitivity, PPV and area under the AFROC curve on set 1 were similar to set 2, including lesions <1 cm. CONCLUSION: In detecting liver metastases from colorectal carcinoma, Images-10 could replace Images-20 in 3.0 T MR imaging.
OBJECTIVE: To compare quantitatively and qualitatively hepatocyte-phase images obtained 10 and 20 min (Images-10, and Images-20) after injection of gadolinium-ethoxybenzyl-diethylenetriamine-pentaacetic acid (Gd-EOB-DTPA) to detect liver metastases from colorectal carcinoma on 3.0 T MR imaging. METHODS: A total of 48 patients (26 men, 22 women; mean age, 64 years) with 88 histopathologically confirmed liver metastases underwent Gd-EOB-DTPA-enhanced MR imaging. Tumour-to-liver contrast-to-noise ratio (CNR), signal intensity gain (SIG) of liver parenchyma and overall image quality were analysed. Two radiologists independently reviewed two sets of MR images: set 1, unenhanced (T1- and T2-weighted), dynamic images and Images-10; set 2, unenhanced, dynamic and Images-20. Sensitivity and positive predictive value (PPV) to detect liver metastases, and diagnostic performance using the alternative free-response receiver operating characteristics (AFROC) method were calculated. RESULTS: The mean tumour-to-liver CNR, SIG of liver parenchyma and overall image quality on Images-20 were significantly higher than those on Images-10. The overall image quality of "fair to excellent" was achieved on both images in 93.8% of the patients. Sensitivity, PPV and area under the AFROC curve on set 1 were similar to set 2, including lesions <1 cm. CONCLUSION: In detecting liver metastases from colorectal carcinoma, Images-10 could replace Images-20 in 3.0 T MR imaging.
Authors: Christoph J Zech; Luigi Grazioli; Josy Breuer; Maximilian F Reiser; Stefan O Schoenberg Journal: Invest Radiol Date: 2008-07 Impact factor: 6.016
Authors: Mustafa R Bashir; Steven R Breault; Ryan Braun; Richard K Do; Rendon C Nelson; Scott B Reeder Journal: Acad Radiol Date: 2014-04-06 Impact factor: 3.173
Authors: Guilherme Moura Cunha; Kyle A Hasenstab; Atsushi Higaki; Kang Wang; Timo Delgado; Ryan L Brunsing; Alexandra Schlein; Armin Schwartzman; Albert Hsiao; Claude B Sirlin; Katie J Fowler Journal: Eur J Radiol Date: 2020-01-14 Impact factor: 3.528