INTRODUCTION: The Woven Endobridge (WEB II) device (Sequent Medical, Inc., Aliso Viejo, CA, USA) is an intra-saccular, oblate, braided-wire embolization device designed to provide flow disruption at the aneurysm neck-parent artery interface. The purpose of this study was to evaluate the acute and short-term performance of the WEB II device regarding the immediacy, degree, and durability of aneurysm occlusion in two patients. METHODS: The WEB II device was implanted in one patient with an unruptured MCA trifurcation aneurysm and one patient with an unruptured basilar tip aneurysm. The degree of intra-aneurysmal flow disruption was graded based on serial digital subtraction aneurysm angiography performed over 30 min immediately following device implantation and at 8 weeks. Immediate and 8-week post-treatment CT and 3-T MRI studies were also performed. RESULTS: Delivery and deployment of the WEB II device was technically straightforward and achieved without complications. Neither device required retrieval or repositioning after full deployment. There were no peri-procedural thrombembolic or hemorrhagic complications. In both cases, complete aneurysm occlusion was observed within minutes of device deployment. Short-term angiographic follow-up confirmed stable complete occlusion at 8 weeks. CONCLUSION: Early technical and clinical results from the first WEB II cases have been encouraging and suggest that the intra-saccular deployment of self-expanding, compliant, cylindrical, high-density, braided metallic mesh constructs may represent a feasible approach for the endovascular treatment of cerebral aneurysms.
INTRODUCTION: The Woven Endobridge (WEB II) device (Sequent Medical, Inc., Aliso Viejo, CA, USA) is an intra-saccular, oblate, braided-wire embolization device designed to provide flow disruption at the aneurysm neck-parent artery interface. The purpose of this study was to evaluate the acute and short-term performance of the WEB II device regarding the immediacy, degree, and durability of aneurysm occlusion in two patients. METHODS: The WEB II device was implanted in one patient with an unruptured MCA trifurcation aneurysm and one patient with an unruptured basilar tip aneurysm. The degree of intra-aneurysmal flow disruption was graded based on serial digital subtraction aneurysm angiography performed over 30 min immediately following device implantation and at 8 weeks. Immediate and 8-week post-treatment CT and 3-T MRI studies were also performed. RESULTS: Delivery and deployment of the WEB II device was technically straightforward and achieved without complications. Neither device required retrieval or repositioning after full deployment. There were no peri-procedural thrombembolic or hemorrhagic complications. In both cases, complete aneurysm occlusion was observed within minutes of device deployment. Short-term angiographic follow-up confirmed stable complete occlusion at 8 weeks. CONCLUSION: Early technical and clinical results from the first WEB II cases have been encouraging and suggest that the intra-saccular deployment of self-expanding, compliant, cylindrical, high-density, braided metallic mesh constructs may represent a feasible approach for the endovascular treatment of cerebral aneurysms.
Authors: Z Kulcsár; E Houdart; A Bonafé; G Parker; J Millar; A J P Goddard; S Renowden; G Gál; B Turowski; K Mitchell; F Gray; M Rodriguez; R van den Berg; A Gruber; H Desal; I Wanke; D A Rüfenacht Journal: AJNR Am J Neuroradiol Date: 2010-11-11 Impact factor: 3.825
Authors: I Szikora; Z Berentei; Z Kulcsar; M Marosfoi; Z S Vajda; W Lee; A Berez; P K Nelson Journal: AJNR Am J Neuroradiol Date: 2010-02-11 Impact factor: 3.825
Authors: C Ulfert; J Pfaff; S Schönenberger; J Bösel; C Herweh; M Pham; M Bendszus; M Möhlenbruch Journal: Clin Neuroradiol Date: 2016-09-16 Impact factor: 3.649
Authors: Fernando Mut; Bong Jae Chung; Jorge Chudyk; Pedro Lylyk; Ramanathan Kadirvel; David F Kallmes; Juan R Cebral Journal: Int J Numer Method Biomed Eng Date: 2019-04-11 Impact factor: 2.747
Authors: J Caroff; C Mihalea; H Neki; D Ruijters; L Ikka; N Benachour; J Moret; L Spelle Journal: AJNR Am J Neuroradiol Date: 2014-02-13 Impact factor: 3.825