Literature DB >> 21344553

Amides as excellent mimics of phosphate linkages in RNA.

Chelliah Selvam1, Siji Thomas, Jason Abbott, Scott D Kennedy, Eriks Rozners.   

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Year:  2011        PMID： 21344553      PMCID： PMC3516995          DOI： 10.1002/anie.201007012

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  13 in total

1.  RNA-Binding affinities and crystal structure of oligonucleotides containing five-atom amide-based backbone structures.

Authors:  Pradeep S Pallan; Peter von Matt; Christopher J Wilds; Karl-Heinz Altmann; Martin Egli
Journal:  Biochemistry       Date:  2006-07-04       Impact factor: 3.162

2.  Solid-phase synthesis of modified RNAs containing amide-linked oligoribonucleosides at their 3'-end and their application to siRNA.

Authors:  Reiko Iwase; Takaaki Toyama; Kengo Nishimori
Journal:  Nucleosides Nucleotides Nucleic Acids       Date:  2007       Impact factor: 1.381

Review 3.  Chemical modification: the key to clinical application of RNA interference?

Authors:  David R Corey
Journal:  J Clin Invest       Date:  2007-12       Impact factor: 14.808

4.  Effects of hydration, ion release, and excluded volume on the melting of triplex and duplex DNA.

Authors:  C H Spink; J B Chaires
Journal:  Biochemistry       Date:  1999-01-05       Impact factor: 3.162

5.  Determination of nucleic acid hydration using osmotic stress.

Authors:  Eriks Rozners
Journal:  Curr Protoc Nucleic Acid Chem       Date:  2010-12

6.  Synthesis and properties of RNA analogues having amides as interuridine linkages at selected positions.

Authors:  Eriks Rozners; Dace Katkevica; Erika Bizdena; Roger Strömberg
Journal:  J Am Chem Soc       Date:  2003-10-08       Impact factor: 15.419

7.  RNA internal loops with tandem AG pairs: the structure of the 5'GAGU/3'UGAG loop can be dramatically different from others, including 5'AAGU/3'UGAA.

Authors:  Nicholas B Hammond; Blanton S Tolbert; Ryszard Kierzek; Douglas H Turner; Scott D Kennedy
Journal:  Biochemistry       Date:  2010-07-13       Impact factor: 3.162

8.  Water and ion binding around r(UpA)12 and d(TpA)12 oligomers--comparison with RNA and DNA (CpG)12 duplexes.

Authors:  P Auffinger; E Westhof
Journal:  J Mol Biol       Date:  2001-02-02       Impact factor: 5.469

9.  Interplay of structure, hydration and thermal stability in formacetal modified oligonucleotides: RNA may tolerate nonionic modifications better than DNA.

Authors:  Andrej Kolarovic; Emma Schweizer; Emily Greene; Mark Gironda; Pradeep S Pallan; Martin Egli; Eriks Rozners
Journal:  J Am Chem Soc       Date:  2009-10-21       Impact factor: 15.419

10.  Hydration of short DNA, RNA and 2'-OMe oligonucleotides determined by osmotic stressing.

Authors:  Eriks Rozners; Janelle Moulder
Journal:  Nucleic Acids Res       Date:  2004-01-09       Impact factor: 16.971
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  16 in total

1.  Concurrent Hydrogenation of Three Functional Groups Enables Synthesis of C3'-Homologated Nucleoside Amino Acids.

Authors:  Venubabu Kotikam; Eriks Rozners
Journal:  Org Lett       Date:  2017-07-21       Impact factor: 6.005

2.  Synthesis and Biological Activity of Short Interfering RNAs Having Several Consecutive Amide Internucleoside Linkages.

Authors:  Venubabu Kotikam; Julien A Viel; Eriks Rozners
Journal:  Chemistry       Date:  2019-12-17       Impact factor: 5.236

3.  A Single Amide Linkage in the Passenger Strand Suppresses Its Activity and Enhances Guide Strand Targeting of siRNAs.

Authors:  Travis Hardcastle; Irina Novosjolova; Venubabu Kotikam; Samwel K Cheruiyot; Daniel Mutisya; Scott D Kennedy; Martin Egli; Melissa L Kelley; Anja van Brabant Smith; Eriks Rozners
Journal:  ACS Chem Biol       Date:  2018-01-10       Impact factor: 5.100

Review 4.  Therapeutic potential of chemically modified siRNA: Recent trends.

Authors:  Chelliah Selvam; Daniel Mutisya; Sandhya Prakash; Kasturi Ranganna; Ramasamy Thilagavathi
Journal:  Chem Biol Drug Des       Date:  2017-05-16       Impact factor: 2.817

5.  Synthesis and properties of triazole-linked RNA.

Authors:  Daniel Mutisya; Chelliah Selvam; Scott D Kennedy; Eriks Rozners
Journal:  Bioorg Med Chem Lett       Date:  2011-04-05       Impact factor: 2.823

6.  An LNA-amide modification that enhances the cell uptake and activity of phosphorothioate exon-skipping oligonucleotides.

Authors:  Ysobel R Baker; Cameron Thorpe; Jinfeng Chen; Laura M Poller; Lina Cox; Pawan Kumar; Wooi F Lim; Lillian Lie; Graham McClorey; Sven Epple; Daniel Singleton; Michael A McDonough; Jack S Hardwick; Kirsten E Christensen; Matthew J A Wood; James P Hall; Afaf H El-Sagheer; Tom Brown
Journal:  Nat Commun       Date:  2022-07-12       Impact factor: 17.694

7.  Synthesis, biophysical studies and RNA interference activity of RNA having three consecutive amide linkages.

Authors:  Paul Tanui; Scott D Kennedy; Benjamin D Lunstad; Amanda Haas; Devin Leake; Eriks Rozners
Journal:  Org Biomol Chem       Date:  2014-02-28       Impact factor: 3.876

8.  Amide-Modified RNA: Using Protein Backbone to Modulate Function of Short Interfering RNAs.

Authors:  Venubabu Kotikam; Eriks Rozners
Journal:  Acc Chem Res       Date:  2020-07-13       Impact factor: 22.384

9.  Synthesis and gene silencing properties of siRNAs containing terminal amide linkages.

Authors:  Maria Gaglione; M Emilia Mercurio; Nicoletta Potenza; Nicola Mosca; Aniello Russo; Ettore Novellino; Sandro Cosconati; Anna Messere
Journal:  Biomed Res Int       Date:  2014-03-26       Impact factor: 3.411

10.  Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs.

Authors:  Daniel Mutisya; Chelliah Selvam; Benjamin D Lunstad; Pradeep S Pallan; Amanda Haas; Devin Leake; Martin Egli; Eriks Rozners
Journal:  Nucleic Acids Res       Date:  2014-05-09       Impact factor: 16.971
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