PURPOSE: To evaluate the image quality of an iterative reconstruction algorithm (IRIS) in low-dose chest CT in comparison with standard-dose filtered back projection (FBP) CT. MATERIALS AND METHODS: Eighty consecutive patients referred for a follow-up chest CT examination of the chest, underwent a low-dose CT examination (Group 2) in similar technical conditions to those of the initial examination, (Group 1) except for the milliamperage selection and the replacement of regular FBP reconstruction by iterative reconstructions using three (Group 2a) and five iterations (Group 2b). RESULTS: Despite a mean decrease of 35.5% in the dose-length-product, there was no statistically significant difference between Group 2a and Group 1 in the objective noise, signal-to-noise (SNR) and contrast-to-noise (CNR) ratios and distribution of the overall image quality scores. Compared to Group 1, objective image noise in Group 2b was significantly reduced with increased SNR and CNR and a trend towards improved image quality. CONCLUSION: Iterative reconstructions using three iterations provide similar image quality compared with the conventionally used FBP reconstruction at 35% less dose, thus enabling dose reduction without loss of diagnostic information. According to our preliminary results, even higher dose reductions than 35% may be feasible by using more than three iterations.
PURPOSE: To evaluate the image quality of an iterative reconstruction algorithm (IRIS) in low-dose chest CT in comparison with standard-dose filtered back projection (FBP) CT. MATERIALS AND METHODS: Eighty consecutive patients referred for a follow-up chest CT examination of the chest, underwent a low-dose CT examination (Group 2) in similar technical conditions to those of the initial examination, (Group 1) except for the milliamperage selection and the replacement of regular FBP reconstruction by iterative reconstructions using three (Group 2a) and five iterations (Group 2b). RESULTS: Despite a mean decrease of 35.5% in the dose-length-product, there was no statistically significant difference between Group 2a and Group 1 in the objective noise, signal-to-noise (SNR) and contrast-to-noise (CNR) ratios and distribution of the overall image quality scores. Compared to Group 1, objective image noise in Group 2b was significantly reduced with increased SNR and CNR and a trend towards improved image quality. CONCLUSION: Iterative reconstructions using three iterations provide similar image quality compared with the conventionally used FBP reconstruction at 35% less dose, thus enabling dose reduction without loss of diagnostic information. According to our preliminary results, even higher dose reductions than 35% may be feasible by using more than three iterations.
Authors: Marco Das; Andreas Horst Mahnken; Georg Mühlenbruch; Achim Stargardt; Claudia Weiss; Dirk-Alexander Sennst; Thomas G Flohr; Rolf W Günther; Joachim Ernst Wildberger Journal: AJR Am J Roentgenol Date: 2005-05 Impact factor: 3.959
Authors: Virginia Tsapaki; John E Aldrich; Raju Sharma; Maria Anna Staniszewska; Anchali Krisanachinda; Madan Rehani; Alan Hufton; Chariklia Triantopoulou; Petros N Maniatis; John Papailiou; Mathias Prokop Journal: Radiology Date: 2006-07-12 Impact factor: 11.105
Authors: A Korn; M Fenchel; B Bender; S Danz; T K Hauser; D Ketelsen; T Flohr; C D Claussen; M Heuschmid; U Ernemann; H Brodoefel Journal: AJNR Am J Neuroradiol Date: 2011-10-27 Impact factor: 3.825
Authors: Stephan Baumueller; Anna Winklehner; Christoph Karlo; Robert Goetti; Thomas Flohr; Erich W Russi; Thomas Frauenfelder; Hatem Alkadhi Journal: Eur Radiol Date: 2012-06-15 Impact factor: 5.315
Authors: Andreas Christe; Johannes Heverhagen; Christoph Ozdoba; Christian Weisstanner; Stefan Ulzheimer; Lukas Ebner Journal: World J Radiol Date: 2013-11-28