Literature DB >> 20966323

Dual-source dual-energy CT with additional tin filtration: Dose and image quality evaluation in phantoms and in vivo.

Andrew N Primak1, Juan Carlos Ramirez Giraldo, Christian D Eusemann, Bernhard Schmidt, Birgit Kantor, Joel G Fletcher, Cynthia H McCollough.   

Abstract

OBJECTIVE: The objective of this study was to investigate the effect on radiation dose and image quality of the use of additional spectral filtration for dual-energy CT using dual-source CT (DSCT).
MATERIALS AND METHODS: A commercial DSCT scanner was modified by adding tin filtration to the high-kV tube, and radiation output and noise were measured in water phantoms. Dose values for equivalent image noise were compared between the dual-energy mode with and without tin filtration and the single-energy mode. To evaluate dual-energy CT material discrimination, the material-specific dual-energy ratio for calcium and that for iodine were determined using images of anthropomorphic phantoms. Data were additionally acquired from imaging a 38-kg pig and an 87-kg pig, and the noise of the linearly mixed images and virtual noncontrast images was compared between dual-energy modes. Finally, abdominal dual-energy CT images of two patients of similar sizes undergoing clinically indicated CT were compared.
RESULTS: Adding tin filtration to the high-kV tube improved the dual-energy contrast between iodine and calcium as much as 290%. Data from our animal study showed that tin filtration had no effect on noise in the dual-energy CT mixed images but decreased noise by as much as 30% in the virtual noncontrast images. Virtual noncontrast images of patients acquired using 100 and 140 kV with added tin filtration had improved image quality relative to those generated using 80 and 140 kV without tin filtration.
CONCLUSION: Tin filtration of the high-kV tube of a DSCT scanner increases the ability of dual-energy CT to discriminate between calcium and iodine without increasing dose relative to single-energy CT. Furthermore, the use of 100- and 140-kV tube potentials allows improved dual-energy CT imaging of large patients.

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Year:  2010        PMID: 20966323      PMCID: PMC2963033          DOI: 10.2214/AJR.09.3956

Source DB:  PubMed          Journal:  AJR Am J Roentgenol        ISSN: 0361-803X            Impact factor:   3.959


  38 in total

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Authors:  Justin L Ducote; Tong Xu; Sabee Molloi
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2.  First performance evaluation of a dual-source CT (DSCT) system.

Authors:  Thomas G Flohr; Cynthia H McCollough; Herbert Bruder; Martin Petersilka; Klaus Gruber; Christoph Süss; Michael Grasruck; Karl Stierstorfer; Bernhard Krauss; Rainer Raupach; Andrew N Primak; Axel Küttner; Stefan Achenbach; Christoph Becker; Andreas Kopp; Bernd M Ohnesorge
Journal:  Eur Radiol       Date:  2005-12-10       Impact factor: 5.315

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6.  Split-filter computed tomography: a simple technique for dual energy scanning.

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8.  Dual-energy mammography: a detector analysis.

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  43 in total

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4.  Single- and dual-energy CT of the abdomen: comparison of radiation dose and image quality of 2nd and 3rd generation dual-source CT.

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5.  Reduction of Metal Artifacts and Improvement in Dose Efficiency Using Photon-Counting Detector Computed Tomography and Tin Filtration.

Authors:  Wei Zhou; David J Bartlett; Felix E Diehn; Katrina N Glazebrook; Amy L Kotsenas; Rickey E Carter; Joel G Fletcher; Cynthia H McCollough; Shuai Leng
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6.  Comparison of image quality and radiation dose of different pulmonary CTA protocols on a 128-slice CT: high-pitch dual source CT, dual energy CT and conventional spiral CT.

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7.  Scatter correction associated with dedicated dual-source CT hardware improves accuracy of lung air measures.

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10.  Dual-energy computed tomography imaging of atherosclerotic plaques in a mouse model using a liposomal-iodine nanoparticle contrast agent.

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