Literature DB >> 20046796

Investigation of Depth of Interaction Encoding for a Pixelated LSO Array with a Single Multi-Channel PMT.

Yongfeng Yang1, Yibao Wu, Simon R Cherry.   

Abstract

A new approach to depth of interaction (DOI) encoding for a pixelated LSO array using a single multi-channel PMT was investigated. In this method the DOI information was estimated by taking advantage of optical crosstalk between LSO elements and examining the standard deviation (spread) of signals on all channels of the PMT. Unpolished and polished 6×6 LSO arrays with a crystal size of 1.3×1.3×20 mm(3) were evaluated on a Hamamatsu H7546 64-channel PMT. The arrays were placed on the center of the PMT and the central 16 channels of the PMT were individually read out and digitized. For the unpolished array, all crystals were resolved in the flood histogram. An average DOI resolution of 8 mm was obtained. The energy resolution was ∼25% after the signal amplitude was corrected using the measured DOI information. For the polished array, the flood histogram was superior to the unpolished array, however no DOI information could be measured. Using unpolished crystals, this method could be a practical way to achieve limited DOI information in PET detectors. The standard deviation of all PMT channels can be readily obtained using a resistor network. Only five signals (four signals to determine the x-y position and one signal measuring the standard deviation) need to be digitized, and this method only requires a single photon detector to read out the array. Unlike phoswich detectors, the method does not require segmenting the scintillator array into layers. The measured DOI resolution was much worse than that obtained with the dual-ended readout method, however, it was similar to that obtained with a two-layer phoswich detector.

Entities:  

Year:  2009        PMID: 20046796      PMCID: PMC2799034          DOI: 10.1109/TNS.2009.2016094

Source DB:  PubMed          Journal:  IEEE Trans Nucl Sci        ISSN: 0018-9499            Impact factor:   1.679


  24 in total

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Authors:  Yuan-Chuan Tai; Arion F Chatziioannou; Yongfeng Yang; Robert W Silverman; Ken Meadors; Stefan Siegel; Danny F Newport; Jennifer R Stickel; Simon R Cherry
Journal:  Phys Med Biol       Date:  2003-06-07       Impact factor: 3.609

2.  Evaluation of high performance data acquisition boards for simultaneous sampling of fast signals from PET detectors.

Authors:  Martin S Judenhofer; Bernd J Pichler; Simon R Cherry
Journal:  Phys Med Biol       Date:  2005-01-07       Impact factor: 3.609

Review 3.  Multimodality in vivo imaging systems: twice the power or double the trouble?

Authors:  Simon R Cherry
Journal:  Annu Rev Biomed Eng       Date:  2006       Impact factor: 9.590

4.  Simultaneous acquisition of multislice PET and MR images: initial results with a MR-compatible PET scanner.

Authors:  Ciprian Catana; Yibao Wu; Martin S Judenhofer; Jinyi Qi; Bernd J Pichler; Simon R Cherry
Journal:  J Nucl Med       Date:  2006-12       Impact factor: 10.057

Review 5.  The 2006 Henry N. Wagner Lecture: Of mice and men (and positrons)--advances in PET imaging technology.

Authors:  Simon R Cherry
Journal:  J Nucl Med       Date:  2006-11       Impact factor: 10.057

6.  Depth of interaction decoding of a continuous crystal detector module.

Authors:  T Ling; T K Lewellen; R S Miyaoka
Journal:  Phys Med Biol       Date:  2007-03-29       Impact factor: 3.609

7.  Measurements of wavelength shifting (WLS) fibre readout for a highly multiplexed, depth-encoding PET detector.

Authors:  Huini Du; Yongfeng Yang; Simon R Cherry
Journal:  Phys Med Biol       Date:  2007-04-10       Impact factor: 3.609

8.  Performance evaluation of the GE healthcare eXplore VISTA dual-ring small-animal PET scanner.

Authors:  Yuchuan Wang; Jurgen Seidel; Benjamin M W Tsui; Juan J Vaquero; Martin G Pomper
Journal:  J Nucl Med       Date:  2006-11       Impact factor: 10.057

Review 9.  Recent developments in PET detector technology.

Authors:  Tom K Lewellen
Journal:  Phys Med Biol       Date:  2008-08-11       Impact factor: 3.609

10.  A microPET/CT system for in vivo small animal imaging.

Authors:  H Liang; Y Yang; K Yang; Y Wu; J M Boone; S R Cherry
Journal:  Phys Med Biol       Date:  2007-06-04       Impact factor: 3.609

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  6 in total

1.  Evaluation of Matrix9 silicon photomultiplier array for small-animal PET.

Authors:  Junwei Du; Jeffrey P Schmall; Yongfeng Yang; Kun Di; Emilie Roncali; Gregory S Mitchell; Steve Buckley; Carl Jackson; Simon R Cherry
Journal:  Med Phys       Date:  2015-02       Impact factor: 4.071

2.  Simulation of light transport in scintillators based on 3D characterization of crystal surfaces.

Authors:  Emilie Roncali; Simon R Cherry
Journal:  Phys Med Biol       Date:  2013-03-11       Impact factor: 3.609

3.  Simulation study of light transport in laser-processed LYSO:Ce detectors with single-side readout.

Authors:  L Bläckberg; G El Fakhri; H Sabet
Journal:  Phys Med Biol       Date:  2017-10-19       Impact factor: 3.609

4.  Experimental evaluation of depth-of-interaction correction in a small-animal positron emission tomography scanner.

Authors:  Michael V Green; Harold G Ostrow; Jurgen Seidel; Martin G Pomper
Journal:  Mol Imaging       Date:  2010-12       Impact factor: 4.488

5.  Crystal identification in positron emission tomography using nonrigid registration to a Fourier-based template.

Authors:  Abhijit J Chaudhari; Anand A Joshi; Spencer L Bowen; Richard M Leahy; Simon R Cherry; Ramsey D Badawi
Journal:  Phys Med Biol       Date:  2008-08-22       Impact factor: 3.609

6.  Characterization of a high-resolution hybrid DOI detector for a dedicated breast PET/CT scanner.

Authors:  Felipe Godinez; Abhijit J Chaudhari; Yongfeng Yang; Richard Farrell; Ramsey D Badawi
Journal:  Phys Med Biol       Date:  2012-05-11       Impact factor: 3.609

  6 in total

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