Literature DB >> 19667802

Characterization of a 137Cs irradiator from a new perspective with modern dosimetric tools.

Samuel L Brady1, Greta Toncheva, Mark W Dewhirst, Terry T Yoshizumi.   

Abstract

To provide for accurate dosimetry in a 137Cs irradiator, the following were investigated: (1) correct mapping of the irradiator cavity's dose distribution, (2) rotated versus stationary dose rate measurements, (3) exposure-to-dose calibration selection for exposure time calculation, and (4) irradiator-timer error correction. This work introduces techniques to map dose distributions and measure dose rates with new high-sensitivity radiochromic films and a small-volume ion chamber constructed for in-beam, high-intensity gamma irradiation. Measured film distributions were compared to manufacturer-provided data and independent measurements from an ion chamber and TLD-100 chips. Measured film distributions agreed with the manufacturer-provided data in the central-vertical region, but disagreed by as much as 95% in surrounding regions. The independent measurements agreed within 96% with the measured dose distribution. Dose rates varied by approximately 11% for a rotational versus stationary setup, by approximately 10% for the dose-to-medium correction between air and soft tissue, and by approximately 4-12% for irradiation times from 0.2-0.7 min due to timer error. In conclusion, a critical irradiator characterization should be performed, initially, as a part of the acceptance testing of a newly installed irradiator, and periodically as an ongoing quality assurance protocol. We investigated, and recommend as part of a comprehensive irradiator verification protocol, the inclusion of radiochromic film-measured dose distributions, dose rates measured during rotation when samples are likewise rotated for exposure, timer error corrections for short-time irradiation, and exposure-to-dose corrections that reflect typical sample compositions, e.g., soft tissue or air.

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Year:  2009        PMID: 19667802      PMCID: PMC3721518          DOI: 10.1097/HP.0b013e3181a9bd42

Source DB:  PubMed          Journal:  Health Phys        ISSN: 0017-9078            Impact factor:   1.316


  19 in total

1.  Dependence of radiochromic film response kinetics on fractionated doses.

Authors:  I Ali; J F Williamson; C Costescu; J F Dempsey
Journal:  Appl Radiat Isot       Date:  2005-04       Impact factor: 1.513

2.  Precise radiochromic film dosimetry using a flat-bed document scanner.

Authors:  Slobodan Devic; Jan Seuntjens; Edwin Sham; Ervin B Podgorsak; C Ross Schmidtlein; Assen S Kirov; Christopher G Soares
Journal:  Med Phys       Date:  2005-07       Impact factor: 4.071

3.  Post-irradiation colouration of Gafchromic EBT radiochromic film.

Authors:  Tsang Cheung; Martin J Butson; Peter K N Yu
Journal:  Phys Med Biol       Date:  2005-10-04       Impact factor: 3.609

4.  Characterization and real-time optical measurements of the ionizing radiation dose response for a new radiochromic medium.

Authors:  Alexandra Rink; I Alex Vitkin; David A Jaffray
Journal:  Med Phys       Date:  2005-08       Impact factor: 4.071

5.  Energy dependence of response of new high sensitivity radiochromic films for megavoltage and kilovoltage radiation energies.

Authors:  Sou-Tung Chiu-Tsao; Yunsil Ho; Ravi Shankar; Lin Wang; Louis B Harrison
Journal:  Med Phys       Date:  2005-11       Impact factor: 4.071

6.  Absorption spectra variations of EBT radiochromic film from radiation exposure.

Authors:  M J Butson; T Cheung; P K N Yu
Journal:  Phys Med Biol       Date:  2005-06-22       Impact factor: 3.609

7.  Weak energy dependence of EBT gafchromic film dose response in the 50 kVp-10 MVp X-ray range.

Authors:  Martin J Butson; Tsang Cheung; Peter K N Yu
Journal:  Appl Radiat Isot       Date:  2005-08-18       Impact factor: 1.513

8.  Accurate dosimetry with GafChromic EBT film of a 6 MV photon beam in water: what level is achievable?

Authors:  L J van Battum; D Hoffmans; H Piersma; S Heukelom
Journal:  Med Phys       Date:  2008-02       Impact factor: 4.071

9.  Radiochromic film dosimetry: recommendations of AAPM Radiation Therapy Committee Task Group 55. American Association of Physicists in Medicine.

Authors:  A Niroomand-Rad; C R Blackwell; B M Coursey; K P Gall; J M Galvin; W L McLaughlin; A S Meigooni; R Nath; J E Rodgers; C G Soares
Journal:  Med Phys       Date:  1998-11       Impact factor: 4.071

10.  A study of GafChromic XR Type R film response with reflective-type densitometers and economical flatbed scanners.

Authors:  G Thomas; R Y L Chu; Frank Rabe
Journal:  J Appl Clin Med Phys       Date:  2003       Impact factor: 2.102

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  5 in total

1.  Isodose curve mappings measured while undergoing rotation for quality assurance testing of a 137Cs irradiator.

Authors:  Samuel L Brady; Terry T Yoshizumi; Colin Anderson-Evans; Giao Nguyen
Journal:  Health Phys       Date:  2012-02       Impact factor: 1.316

2.  Dosimetry Formalism and Implementation of a Homogenous Irradiation Protocol to Improve the Accuracy of Small Animal Whole-Body Irradiation Using a 137Cs Irradiator.

Authors:  N Patrik Brodin; Yong Chen; Ravindra Yaparpalvi; Chandan Guha; Wolfgang A Tomé
Journal:  Health Phys       Date:  2016-02       Impact factor: 1.316

3.  Specific issues in small animal dosimetry and irradiator calibration.

Authors:  Terry Yoshizumi; Samuel L Brady; Mike E Robbins; J Daniel Bourland
Journal:  Int J Radiat Biol       Date:  2011-10       Impact factor: 2.694

4.  Modern dosimetric tools for (60)Co irradiation at high containment laboratories.

Authors:  Barri Twardoski; Heinz Feldmann; Marshall E Bloom; Joe Ward
Journal:  Int J Radiat Biol       Date:  2011-10       Impact factor: 2.694

5.  Salivary glands regenerate after radiation injury through SOX2-mediated secretory cell replacement.

Authors:  Elaine Emmerson; Alison J May; Lionel Berthoin; Noel Cruz-Pacheco; Sara Nathan; Aaron J Mattingly; Jolie L Chang; William R Ryan; Aaron D Tward; Sarah M Knox
Journal:  EMBO Mol Med       Date:  2018-03       Impact factor: 12.137

  5 in total

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