Literature DB >> 19374124

Biosynthesis of polyketide synthase extender units.

Yolande A Chan1, Angela M Podevels, Brian M Kevany, Michael G Thomas.   

Abstract

This review covers the biosynthesis of extender units that are utilized for the assembly of polyketides by polyketide synthases. The metabolic origins of each of the currently known polyketide synthase extender units are covered.

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Year:  2009        PMID: 19374124      PMCID: PMC2766543          DOI: 10.1039/b801658p

Source DB:  PubMed          Journal:  Nat Prod Rep        ISSN: 0265-0568            Impact factor:   13.423


  124 in total

1.  Identification of a set of genes involved in the formation of the substrate for the incorporation of the unusual "glycolate" chain extension unit in ansamitocin biosynthesis.

Authors:  Brian J Carroll; Steven J Moss; Linquan Bai; Yasuo Kato; Sabine Toelzer; Tin-Wein Yu; Heinz G Floss
Journal:  J Am Chem Soc       Date:  2002-04-24       Impact factor: 15.419

2.  Genetic characterization of the chlorothricin gene cluster as a model for spirotetronate antibiotic biosynthesis.

Authors:  Xin-Ying Jia; Zhen-Hua Tian; Lei Shao; Xu-Dong Qu; Qun-Fei Zhao; Jian Tang; Gong-Li Tang; Wen Liu
Journal:  Chem Biol       Date:  2006-06

3.  Biosynthetic origin of the C2 units of geldanamycin and distribution of label from D-[6-13C]glucose.

Authors:  A Haber; R D Johnson; K L Rinehart
Journal:  J Am Chem Soc       Date:  1977-05-11       Impact factor: 15.419

4.  A new substrate specificity for acyl transferase domains of the ascomycin polyketide synthase in Streptomyces hygroscopicus.

Authors:  Christopher D Reeves; Loleta M Chung; Yaoquan Liu; Qun Xue; John R Carney; W Peter Revill; Leonard Katz
Journal:  J Biol Chem       Date:  2002-01-10       Impact factor: 5.157

Review 5.  Polyketide biosynthesis beyond the type I, II and III polyketide synthase paradigms.

Authors:  Ben Shen
Journal:  Curr Opin Chem Biol       Date:  2003-04       Impact factor: 8.822

6.  The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.

Authors:  K Wu; L Chung; W P Revill; L Katz; C D Reeves
Journal:  Gene       Date:  2000-06-13       Impact factor: 3.688

7.  Crystal structure of the beta-subunit of acyl-CoA carboxylase: structure-based engineering of substrate specificity.

Authors:  Lautaro Diacovich; Deborah Lynn Mitchell; Huy Pham; Gabriela Gago; Melrose Mendoza Melgar; Chaitan Khosla; Hugo Gramajo; Shiou-Chuan Tsai
Journal:  Biochemistry       Date:  2004-11-09       Impact factor: 3.162

8.  Isolation of galantins I and II, water-soluble basic peptides. Studies on antibiotics from the genus Bacillus. III.

Authors:  J Shoji; R Sakazaki; Y Wakisaka; K Koizumi; M Mayama; S Matsuura
Journal:  J Antibiot (Tokyo)       Date:  1975-02       Impact factor: 2.649

Review 9.  Malonate metabolism: biochemistry, molecular biology, physiology, and industrial application.

Authors:  Yu Sam Kim
Journal:  J Biochem Mol Biol       Date:  2002-09-30

10.  Ethyl-substituted erythromycin derivatives produced by directed metabolic engineering.

Authors:  D L Stassi; S J Kakavas; K A Reynolds; G Gunawardana; S Swanson; D Zeidner; M Jackson; H Liu; A Buko; L Katz
Journal:  Proc Natl Acad Sci U S A       Date:  1998-06-23       Impact factor: 11.205

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  90 in total

1.  Identification of the biosynthetic gene cluster for the antibiotic polyketide L-155,175 in Streptomyces hygroscopicus.

Authors:  Eun Young Kim; Jae Woo Han; Jee Yeon Lee; Beom Seok Kim
Journal:  Folia Microbiol (Praha)       Date:  2012-06-06       Impact factor: 2.099

2.  Structure-guided expansion of the substrate range of methylmalonyl coenzyme A synthetase (MatB) of Rhodopseudomonas palustris.

Authors:  Heidi A Crosby; Katherine C Rank; Ivan Rayment; Jorge C Escalante-Semerena
Journal:  Appl Environ Microbiol       Date:  2012-07-06       Impact factor: 4.792

Review 3.  Programming of erythromycin biosynthesis by a modular polyketide synthase.

Authors:  David E Cane
Journal:  J Biol Chem       Date:  2010-06-03       Impact factor: 5.157

4.  A novel docking domain interface model predicting recombination between homoeologous modular biosynthetic gene clusters.

Authors:  Antonio Starcevic; Janko Diminic; Jurica Zucko; Mouhsine Elbekali; Tobias Schlosser; Mohamed Lisfi; Ana Vukelic; Paul F Long; Daslav Hranueli; John Cullum
Journal:  J Ind Microbiol Biotechnol       Date:  2010-11-24       Impact factor: 3.346

Review 5.  The biosynthetic pathway of FK506 and its engineering: from past achievements to future prospects.

Authors:  Yeon Hee Ban; Sung Ryeol Park; Yeo Joon Yoon
Journal:  J Ind Microbiol Biotechnol       Date:  2015-09-05       Impact factor: 3.346

6.  Structure-based analysis of the molecular interactions between acyltransferase and acyl carrier protein in vicenistatin biosynthesis.

Authors:  Akimasa Miyanaga; Shohei Iwasawa; Yuji Shinohara; Fumitaka Kudo; Tadashi Eguchi
Journal:  Proc Natl Acad Sci U S A       Date:  2016-02-01       Impact factor: 11.205

Review 7.  Protein engineering towards natural product synthesis and diversification.

Authors:  Angelica O Zabala; Ralph A Cacho; Yi Tang
Journal:  J Ind Microbiol Biotechnol       Date:  2011-10-18       Impact factor: 3.346

8.  Development of a Genetically Encoded Biosensor for Detection of Polyketide Synthase Extender Units in Escherichia coli.

Authors:  Edward Kalkreuter; Aaron M Keeler; Alexandra A Malico; Kyle S Bingham; Anuran K Gayen; Gavin J Williams
Journal:  ACS Synth Biol       Date:  2019-05-28       Impact factor: 5.110

9.  Development of a cyanobacterial heterologous polyketide production platform.

Authors:  Julia Roulet; Arnaud Taton; James W Golden; Ana Arabolaza; Michael D Burkart; Hugo Gramajo
Journal:  Metab Eng       Date:  2018-07-21       Impact factor: 9.783

10.  Molecular insights into the biosynthesis of guadinomine: a type III secretion system inhibitor.

Authors:  Tracy C Holmes; Aaron E May; Kathia Zaleta-Rivera; J Graham Ruby; Peter Skewes-Cox; Michael A Fischbach; Joseph L DeRisi; Masato Iwatsuki; Satoshi Ōmura; Chaitan Khosla
Journal:  J Am Chem Soc       Date:  2012-10-10       Impact factor: 15.419

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