Literature DB >> 20522551

Programming of erythromycin biosynthesis by a modular polyketide synthase.

David E Cane1.   

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Year:  2010        PMID： 20522551      PMCID： PMC2934617          DOI： 10.1074/jbc.R110.144618

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


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  66 in total

1.  Quantitative analysis of loading and extender acyltransferases of modular polyketide synthases.

Authors:  Grace F Liou; Janice Lau; David E Cane; Chaitan Khosla
Journal:  Biochemistry       Date:  2003-01-14       Impact factor: 3.162

2.  The structure of docking domains in modular polyketide synthases.

Authors:  R William Broadhurst; Daniel Nietlispach; Michael P Wheatcroft; Peter F Leadlay; Kira J Weissman
Journal:  Chem Biol       Date:  2003-08

3.  MACROLIDE STEREOCHEMISTRY. 3. A CONFIGURATIONAL MODEL FOR MACROLIDE ANTIBIOTICS.

Authors:  W D CELMER
Journal:  J Am Chem Soc       Date:  1965-04-20       Impact factor: 15.419

4.  Organization of the enzymatic domains in the multifunctional polyketide synthase involved in erythromycin formation in Saccharopolyspora erythraea.

Authors:  S Donadio; L Katz
Journal:  Gene       Date:  1992-02-01       Impact factor: 3.688

5.  Erythromycin biosynthesis. The 4-pro-S hydride of NADPH is utilized for ketoreduction by both module 5 and module 6 of the 6-deoxyerythronolide B synthase.

Authors:  Y Yin; R Gokhale; C Khosla; D E Cane
Journal:  Bioorg Med Chem Lett       Date:  2001-06-18       Impact factor: 2.823

6.  Molecular basis of Celmer's rules: stereochemistry of catalysis by isolated ketoreductase domains from modular polyketide synthases.

Authors:  Alexandros P Siskos; Abel Baerga-Ortiz; Shilpa Bali; Viktor Stein; Hassan Mamdani; Dieter Spiteller; Bojana Popovic; Jonathan B Spencer; James Staunton; Kira J Weissman; Peter F Leadlay
Journal:  Chem Biol       Date:  2005-10

7.  Identification of DEBS 1, DEBS 2 and DEBS 3, the multienzyme polypeptides of the erythromycin-producing polyketide synthase from Saccharopolyspora erythraea.

Authors:  P Caffrey; D J Bevitt; J Staunton; P F Leadlay
Journal:  FEBS Lett       Date:  1992-06-15       Impact factor: 4.124

8.  Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases.

Authors:  Penny von Wettstein-Knowles; Johan G Olsen; Kirsten A McGuire; Anette Henriksen
Journal:  FEBS J       Date:  2006-02       Impact factor: 5.542

9.  Evidence for two catalytically independent clusters of active sites in a functional modular polyketide synthase.

Authors:  C M Kao; R Pieper; D E Cane; C Khosla
Journal:  Biochemistry       Date:  1996-09-24       Impact factor: 3.162

Review 10.  Structures and mechanisms of polyketide synthases.

Authors:  Chaitan Khosla
Journal:  J Org Chem       Date:  2009-09-04       Impact factor: 4.354
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  31 in total

1.  Observing the invisible through imaging mass spectrometry, a window into the metabolic exchange patterns of microbes.

Authors:  David J Gonzalez; Yuquan Xu; Yu-Liang Yang; Eduardo Esquenazi; Wei-Ting Liu; Anna Edlund; Tram Duong; Liangcheng Du; István Molnár; William H Gerwick; Paul R Jensen; Michael Fischbach; Chih-Chuang Liaw; Paul Straight; Victor Nizet; Pieter C Dorrestein
Journal:  J Proteomics       Date:  2012-05-26       Impact factor: 4.044

2.  Mechanism and Stereochemistry of Polyketide Chain Elongation and Methyl Group Epimerization in Polyether Biosynthesis.

Authors:  Xinqiang Xie; Ashish Garg; Chaitan Khosla; David E Cane
Journal:  J Am Chem Soc       Date:  2017-02-14       Impact factor: 15.419

Review 3.  Lipidomics in translational research and the clinical significance of lipid-based biomarkers.

Authors:  Daniel J Stephenson; L Alexis Hoeferlin; Charles E Chalfant
Journal:  Transl Res       Date:  2017-06-15       Impact factor: 7.012

Review 4.  Enzymatic Cascade Reactions in Biosynthesis.

Authors:  Christopher T Walsh; Bradley S Moore
Journal:  Angew Chem Int Ed Engl       Date:  2019-02-20       Impact factor: 15.336

Review 5.  Thiazolyl peptide antibiotic biosynthesis: a cascade of post-translational modifications on ribosomal nascent proteins.

Authors:  Christopher T Walsh; Michael G Acker; Albert A Bowers
Journal:  J Biol Chem       Date:  2010-06-03       Impact factor: 5.157

Review 6.  Combinatorial biosynthesis of polyketides--a perspective.

Authors:  Fong T Wong; Chaitan Khosla
Journal:  Curr Opin Chem Biol       Date:  2012-02-16       Impact factor: 8.822

7.  A single module type I polyketide synthase directs de novo macrolactone biogenesis during galbonolide biosynthesis in Streptomyces galbus.

Authors:  Hyun-Ju Kim; Suman Karki; So-Yeon Kwon; Si-Hyung Park; Baek-Hie Nahm; Yeon-Ki Kim; Hyung-Jin Kwon
Journal:  J Biol Chem       Date:  2014-10-21       Impact factor: 5.157

8.  Role of a conserved arginine residue in linkers between the ketosynthase and acyltransferase domains of multimodular polyketide synthases.

Authors:  Satoshi Yuzawa; Shiven Kapur; David E Cane; Chaitan Khosla
Journal:  Biochemistry       Date:  2012-04-24       Impact factor: 3.162

9.  Elucidation of the Stereospecificity of C-Methyltransferases from trans-AT Polyketide Synthases.

Authors:  Xinqiang Xie; Chaitan Khosla; David E Cane
Journal:  J Am Chem Soc       Date:  2017-04-25       Impact factor: 15.419

Review 10.  Structural analysis of protein-protein interactions in type I polyketide synthases.

Authors:  Wei Xu; Kangjian Qiao; Yi Tang
Journal:  Crit Rev Biochem Mol Biol       Date:  2012-12-19       Impact factor: 8.250
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