Literature DB >> 12714063

Polyketide biosynthesis beyond the type I, II and III polyketide synthase paradigms.

Ben Shen1.   

Abstract

Recent literature on polyketide biosynthesis suggests that polyketide synthases have much greater diversity in both mechanism and structure than the current type I, II and III paradigms. These examples serve as an inspiration for searching novel polyketide synthases to give new insights into polyketide biosynthesis and to provide new opportunities for combinatorial biosynthesis.

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Year:  2003        PMID： 12714063     DOI： 10.1016/s1367-5931(03)00020-6

Source DB:  PubMed          Journal:  Curr Opin Chem Biol        ISSN： 1367-5931            Impact factor:   8.822


  138 in total

1.  Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model.

Authors:  Wen Liu; Joachim Ahlert; Qunjie Gao; Evelyn Wendt-Pienkowski; Ben Shen; Jon S Thorson
Journal:  Proc Natl Acad Sci U S A       Date:  2003-10-03       Impact factor: 11.205

2.  Development of a mariner-based transposon for use in Sorangium cellulosum.

Authors:  Bryan Julien; Ruby Fehd
Journal:  Appl Environ Microbiol       Date:  2003-10       Impact factor: 4.792

3.  Phylogenetic analysis of polyketide synthase I domains from soil metagenomic libraries allows selection of promising clones.

Authors:  Aurélien Ginolhac; Cyrille Jarrin; Benjamin Gillet; Patrick Robe; Petar Pujic; Karine Tuphile; Hélène Bertrand; Timothy M Vogel; Guy Perrière; Pascal Simonet; Renaud Nalin
Journal:  Appl Environ Microbiol       Date:  2004-09       Impact factor: 4.792

4.  Culturable endophytes of medicinal plants and the genetic basis for their bioactivity.

Authors:  Kristin I Miller; Chen Qing; Daniel Man-Yuen Sze; Basil D Roufogalis; Brett A Neilan
Journal:  Microb Ecol       Date:  2012-03-21       Impact factor: 4.552

5.  Unique actinomycetes from marine caves and coral reef sediments provide novel PKS and NRPS biosynthetic gene clusters.

Authors:  Tyler W Hodges; Marc Slattery; Julie B Olson
Journal:  Mar Biotechnol (NY)       Date:  2011-10-15       Impact factor: 3.619

Review 6.  New insights into the formation of fungal aromatic polyketides.

Authors:  Jason M Crawford; Craig A Townsend
Journal:  Nat Rev Microbiol       Date:  2010-12       Impact factor: 60.633

7.  Probing the selectivity and protein·protein interactions of a nonreducing fungal polyketide synthase using mechanism-based crosslinkers.

Authors:  Joel Bruegger; Robert W Haushalter; Bob Haushalter; Anna L Vagstad; Anna Vagstad; Gaurav Shakya; Nathan Mih; Craig A Townsend; Michael D Burkart; Shiou-Chuan Tsai
Journal:  Chem Biol       Date:  2013-08-29

8.  Probing the compatibility of type II ketosynthase-carrier protein partners.

Authors:  Andrew S Worthington; Gene H Hur; Jordan L Meier; Qian Cheng; Bradley S Moore; Michael D Burkart
Journal:  Chembiochem       Date:  2008-09-01       Impact factor: 3.164

9.  Structural basis for binding specificity between subclasses of modular polyketide synthase docking domains.

Authors:  Tonia J Buchholz; Todd W Geders; Frank E Bartley; Kevin A Reynolds; Janet L Smith; David H Sherman
Journal:  ACS Chem Biol       Date:  2009-01-16       Impact factor: 5.100

10.  Structural characterization of CalO2: a putative orsellinic acid P450 oxidase in the calicheamicin biosynthetic pathway.

Authors:  Jason G McCoy; Heather D Johnson; Shanteri Singh; Craig A Bingman; In-Kyoung Lei; Jon S Thorson; George N Phillips
Journal:  Proteins       Date:  2009-01
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