Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Antimalarial bromophycolides J-Q from the Fijian red alga Callophycus serratus.

Literature DB >> 19271727

Antimalarial bromophycolides J-Q from the Fijian red alga Callophycus serratus.

Amy L Lane¹, E Paige Stout, An-Shen Lin, Jacques Prudhomme, Karine Le Roch, Craig R Fairchild, Scott G Franzblau, Mark E Hay, William Aalbersberg, Julia Kubanek.

Abstract

Bromophycolides J-Q (1-8) were isolated from extracts of the Fijian red alga Callophycus serratus and identified with 1D and 2D NMR spectroscopy and mass spectral analyses. These diterpene-benzoate macrolides represent two novel carbon skeletons and add to the 10 previously reported bromophycolides (9-18) from this alga. Among these 18 bromophycolides, several exhibited activities in the low micromolar range against the human malaria parasite Plasmodium falciparum.

Entities: CellLine Chemical Disease Gene Mutation Species

Mesh：

Substances：
Antimalarials
Diterpenes

Year: 2009 PMID： 19271727 PMCID： PMC2707147 DOI： 10.1021/jo900008w

Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354

16 in total

Review 1. Highlights of marine natural products chemistry (1972-1999).

Authors: D J Faulkner
Journal: Nat Prod Rep Date: 2000-02 Impact factor: 13.423

Review 2. Antimalarial drugs - what is in use and what is in the pipeline.

Authors: Martin Schlitzer
Journal: Arch Pharm (Weinheim) Date: 2008-03 Impact factor: 3.751

3. In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.

Authors: Kanakeshwari Falzari; Zhaohai Zhu; Dahua Pan; Huiwen Liu; Poonpilas Hongmanee; Scott G Franzblau
Journal: Antimicrob Agents Chemother Date: 2005-04 Impact factor: 5.191

4. Antineoplastic diterpene-benzoate macrolides from the Fijian red alga Callophycus serratus.

Authors: Julia Kubanek; Anne C Prusak; Terry W Snell; Rachel A Giese; Kenneth I Hardcastle; Craig R Fairchild; William Aalbersberg; Carmen Raventos-Suarez; Mark E Hay
Journal: Org Lett Date: 2005-11-10 Impact factor: 6.005

5. The global distribution of clinical episodes of Plasmodium falciparum malaria.

Authors: Robert W Snow; Carlos A Guerra; Abdisalan M Noor; Hla Y Myint; Simon I Hay
Journal: Nature Date: 2005-03-10 Impact factor: 49.962

6. Artemisinin induces apoptosis in human cancer cells.

Authors: Narendra P Singh; Henry C Lai
Journal: Anticancer Res Date: 2004 Jul-Aug Impact factor: 2.480

7. Novel, rapid, and inexpensive cell-based quantification of antimalarial drug efficacy.

Authors: Tyler N Bennett; Michelle Paguio; Bojana Gligorijevic; Clement Seudieu; Andrew D Kosar; Eugene Davidson; Paul D Roepe
Journal: Antimicrob Agents Chemother Date: 2004-05 Impact factor: 5.191

8. Simple and inexpensive fluorescence-based technique for high-throughput antimalarial drug screening.

Authors: Martin Smilkstein; Nongluk Sriwilaijaroen; Jane Xu Kelly; Prapon Wilairat; Michael Riscoe
Journal: Antimicrob Agents Chemother Date: 2004-05 Impact factor: 5.191

9. Human malaria parasites in continuous culture.

Authors: W Trager; J B Jensen
Journal: Science Date: 1976-08-20 Impact factor: 47.728

10. In vitro activity of artemisinin derivatives against African isolates and clones of Plasmodium falciparum.

Authors: L K Basco; J Le Bras
Journal: Am J Trop Med Hyg Date: 1993-09 Impact factor: 2.345

23 in total

1. Structure and biological evaluation of novel cytotoxic sterol glycosides from the marine red alga Peyssonnelia sp.

Authors: An-Shen Lin; Sebastian Engel; Benjamin A Smith; Craig R Fairchild; William Aalbersberg; Mark E Hay; Julia Kubanek
Journal: Bioorg Med Chem Date: 2010-10-28 Impact factor: 3.641

2. Bromophycolide A targets heme crystallization in the human malaria parasite Plasmodium falciparum.

Authors: E Paige Stout; Serena Cervantes; Jacques Prudhomme; Stefan France; James J La Clair; Karine Le Roch; Julia Kubanek
Journal: ChemMedChem Date: 2011-07-05 Impact factor: 3.466

3. Bioactive bromophycolides R-U from the Fijian red alga Callophycus serratus.

Authors: An-Shen Lin; E Paige Stout; Jacques Prudhomme; Karine Le Roch; Craig R Fairchild; Scott G Franzblau; William Aalbersberg; Mark E Hay; Julia Kubanek
Journal: J Nat Prod Date: 2010-02-26 Impact factor: 4.050

Review 4. Antiplasmodial natural products: an update.

Authors: Nasir Tajuddeen; Fanie R Van Heerden
Journal: Malar J Date: 2019-12-05 Impact factor: 2.979

5. Pharmacokinetics, metabolism, and in vivo efficacy of the antimalarial natural product bromophycolide A.

Authors: Margaret E Teasdale; Jacques Prudhomme; Manuel Torres; Matthew Braley; Serena Cervantes; Shanti C Bhatia; James J La Clair; Karine Le Roch; Julia Kubanek
Journal: ACS Med Chem Lett Date: 2013-10-10 Impact factor: 4.345

6. Unusual antimalarial meroditerpenes from tropical red macroalgae.

Authors: E Paige Stout; Jacques Prudhomme; Karine Le Roch; Craig R Fairchild; Scott G Franzblau; William Aalbersberg; Mark E Hay; Julia Kubanek
Journal: Bioorg Med Chem Lett Date: 2010-08-10 Impact factor: 2.823

7. A short asymmetric route to the bromophycolide A and D skeleton.

Authors: Hongkun Lin; Susan S Pochapsky; Isaac J Krauss
Journal: Org Lett Date: 2011-02-10 Impact factor: 6.005

8. Antimalarial Natural Products.

Authors: David G I Kingston; Maria Belen Cassera
Journal: Prog Chem Org Nat Prod Date: 2022

9. Inhibitory effect of a callophycin A derivative on iNOS expression via inhibition of Akt in lipopolysaccharide-stimulated RAW 264.7 cells.

Authors: Eun-Jung Park; Li Shen; Dianqing Sun; John M Pezzuto
Journal: J Nat Prod Date: 2013-12-03 Impact factor: 4.050

10. Bromophycoic acids: bioactive natural products from a Fijian red alga Callophycus sp.

Authors: Margaret E Teasdale; Tonya L Shearer; Sebastian Engel; Troy S Alexander; Craig R Fairchild; Jacques Prudhomme; Manuel Torres; Karine Le Roch; William Aalbersberg; Mark E Hay; Julia Kubanek
Journal: J Org Chem Date: 2012-09-05 Impact factor: 4.354