Literature DB >> 20141173

Bioactive bromophycolides R-U from the Fijian red alga Callophycus serratus.

An-Shen Lin1, E Paige Stout, Jacques Prudhomme, Karine Le Roch, Craig R Fairchild, Scott G Franzblau, William Aalbersberg, Mark E Hay, Julia Kubanek.   

Abstract

Four new bromophycolides, R-U (1-4), were isolated from the Fijian red alga Callophycus serratus and were identified by 1D and 2D NMR and mass spectroscopic analyses. These compounds expand the known structural variety of diterpene-benzoate macrolides and exhibited modest cytotoxicity toward selected human cancer cell lines. Bromophycolide S (2) also showed submicromolar activity against the human malaria parasite Plasmodium falciparum.

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Year:  2010        PMID： 20141173      PMCID： PMC3375676          DOI： 10.1021/np900686w

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  9 in total

1.  BMS-247550: a novel epothilone analog with a mode of action similar to paclitaxel but possessing superior antitumor efficacy.

Authors:  F Y Lee; R Borzilleri; C R Fairchild; S H Kim; B H Long; C Reventos-Suarez; G D Vite; W C Rose; R A Kramer
Journal:  Clin Cancer Res       Date:  2001-05       Impact factor: 12.531

2.  Bromophycolides C-I from the Fijian red alga Callophycus serratus.

Authors:  Julia Kubanek; Anne C Prusak; Terry W Snell; Rachel A Giese; Craig R Fairchild; William Aalbersberg; Mark E Hay
Journal:  J Nat Prod       Date:  2006-05       Impact factor: 4.050

Review 3.  Marine natural products.

Authors:  John W Blunt; Brent R Copp; Wan-Ping Hu; Murray H G Munro; Peter T Northcote; Michèle R Prinsep
Journal:  Nat Prod Rep       Date:  2009-01-06       Impact factor: 13.423

4.  In vitro and in vivo activities of macrolide derivatives against Mycobacterium tuberculosis.

Authors:  Kanakeshwari Falzari; Zhaohai Zhu; Dahua Pan; Huiwen Liu; Poonpilas Hongmanee; Scott G Franzblau
Journal:  Antimicrob Agents Chemother       Date:  2005-04       Impact factor: 5.191

5.  Antineoplastic diterpene-benzoate macrolides from the Fijian red alga Callophycus serratus.

Authors:  Julia Kubanek; Anne C Prusak; Terry W Snell; Rachel A Giese; Kenneth I Hardcastle; Craig R Fairchild; William Aalbersberg; Carmen Raventos-Suarez; Mark E Hay
Journal:  Org Lett       Date:  2005-11-10       Impact factor: 6.005

6.  Callophycoic acids and callophycols from the Fijian red alga Callophycus serratus.

Authors:  Amy L Lane; Elizabeth P Stout; Mark E Hay; Anne C Prusak; Kenneth Hardcastle; Craig R Fairchild; Scott G Franzblau; Karine Le Roch; Jacques Prudhomme; William Aalbersberg; Julia Kubanek
Journal:  J Org Chem       Date:  2007-08-23       Impact factor: 4.354

7.  Simple and inexpensive fluorescence-based technique for high-throughput antimalarial drug screening.

Authors:  Martin Smilkstein; Nongluk Sriwilaijaroen; Jane Xu Kelly; Prapon Wilairat; Michael Riscoe
Journal:  Antimicrob Agents Chemother       Date:  2004-05       Impact factor: 5.191

8.  Antimalarial bromophycolides J-Q from the Fijian red alga Callophycus serratus.

Authors:  Amy L Lane; E Paige Stout; An-Shen Lin; Jacques Prudhomme; Karine Le Roch; Craig R Fairchild; Scott G Franzblau; Mark E Hay; William Aalbersberg; Julia Kubanek
Journal:  J Org Chem       Date:  2009-04-03       Impact factor: 4.354

9.  Desorption electrospray ionization mass spectrometry reveals surface-mediated antifungal chemical defense of a tropical seaweed.

Authors:  Amy L Lane; Leonard Nyadong; Asiri S Galhena; Tonya L Shearer; E Paige Stout; R Mitchell Parry; Mark Kwasnik; May D Wang; Mark E Hay; Facundo M Fernandez; Julia Kubanek
Journal:  Proc Natl Acad Sci U S A       Date:  2009-04-06       Impact factor: 11.205
  9 in total
  16 in total

1.  Bromophycolide A targets heme crystallization in the human malaria parasite Plasmodium falciparum.

Authors:  E Paige Stout; Serena Cervantes; Jacques Prudhomme; Stefan France; James J La Clair; Karine Le Roch; Julia Kubanek
Journal:  ChemMedChem       Date:  2011-07-05       Impact factor: 3.466

Review 2.  Antiplasmodial natural products: an update.

Authors:  Nasir Tajuddeen; Fanie R Van Heerden
Journal:  Malar J       Date:  2019-12-05       Impact factor: 2.979

3.  Pharmacokinetics, metabolism, and in vivo efficacy of the antimalarial natural product bromophycolide A.

Authors:  Margaret E Teasdale; Jacques Prudhomme; Manuel Torres; Matthew Braley; Serena Cervantes; Shanti C Bhatia; James J La Clair; Karine Le Roch; Julia Kubanek
Journal:  ACS Med Chem Lett       Date:  2013-10-10       Impact factor: 4.345

4.  Unusual antimalarial meroditerpenes from tropical red macroalgae.

Authors:  E Paige Stout; Jacques Prudhomme; Karine Le Roch; Craig R Fairchild; Scott G Franzblau; William Aalbersberg; Mark E Hay; Julia Kubanek
Journal:  Bioorg Med Chem Lett       Date:  2010-08-10       Impact factor: 2.823

5.  A short asymmetric route to the bromophycolide A and D skeleton.

Authors:  Hongkun Lin; Susan S Pochapsky; Isaac J Krauss
Journal:  Org Lett       Date:  2011-02-10       Impact factor: 6.005

Review 6.  The structural diversity and promise of antiparasitic marine invertebrate-derived small molecules.

Authors:  Katharine R Watts; Karen Tenney; Phillip Crews
Journal:  Curr Opin Biotechnol       Date:  2010-10-16       Impact factor: 9.740

7.  Bromophycoic acids: bioactive natural products from a Fijian red alga Callophycus sp.

Authors:  Margaret E Teasdale; Tonya L Shearer; Sebastian Engel; Troy S Alexander; Craig R Fairchild; Jacques Prudhomme; Manuel Torres; Karine Le Roch; William Aalbersberg; Mark E Hay; Julia Kubanek
Journal:  J Org Chem       Date:  2012-09-05       Impact factor: 4.354

8.  Bioactivity of seagrass against the dengue fever mosquito Aedes aegypti larvae.

Authors:  M Syed Ali; S Ravikumar; J Margaret Beula
Journal:  Asian Pac J Trop Biomed       Date:  2012-07

9.  Antiprotozoal activities of organic extracts from French marine seaweeds.

Authors:  Catherine Vonthron-Sénécheau; Marcel Kaiser; Isabelle Devambez; Antoine Vastel; Isabelle Mussio; Anne-Marie Rusig
Journal:  Mar Drugs       Date:  2011-05-25       Impact factor: 6.085

10.  High content live cell imaging for the discovery of new antimalarial marine natural products.

Authors:  Serena Cervantes; Paige E Stout; Jacques Prudhomme; Sebastian Engel; Matthew Bruton; Michael Cervantes; David Carter; Young Tae-Chang; Mark E Hay; William Aalbersberg; Julia Kubanek; Karine G Le Roch
Journal:  BMC Infect Dis       Date:  2012-01-03       Impact factor: 3.090
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