PURPOSE: To describe the preoperative and postoperative motility disturbances encountered in the Tube Versus Trabeculectomy (TVT) Study during the first year of follow-up. DESIGN: Multicenter randomized clinical trial. METHODS: settings: Seventeen clinical centers. population: Patients 18 to 85 years old who had previous trabeculectomy and/or cataract surgery and uncontrolled glaucoma with intraocular pressure >; or =18 mm Hg and < or =40 mm Hg on maximum tolerated medical therapy. interventions: 350-mm(2) Baerveldt glaucoma implant or trabeculectomy with mitomycin C (MMC). main outcome measures: Preoperative and postoperative evaluation of ocular motility and diplopia. RESULTS:Motility disturbances were detected in 55 patients (28%) at baseline. New-onset persistent diplopia was reported in 5 patients (5%) in the tube group and no patients in the trabeculectomy group at 1 year (P = .06). A new postoperative motility disturbance developed or worsened in 7 patients (9.9%) in the tube group and no patients in the trabeculectomy group during the first year of follow-up (P = .005). Postoperative motility disturbances were also associated with increasing age (P < .001) and right eye surgery (P = .044). CONCLUSIONS:Preoperative motility disturbances were common among patients in the TVT Study. New postoperative motility disturbances were more frequent following tube shunt surgery than trabeculectomy with MMC after 1 year of follow-up.
RCT Entities:
PURPOSE: To describe the preoperative and postoperative motility disturbances encountered in the Tube Versus Trabeculectomy (TVT) Study during the first year of follow-up. DESIGN: Multicenter randomized clinical trial. METHODS: settings: Seventeen clinical centers. population: Patients 18 to 85 years old who had previous trabeculectomy and/or cataract surgery and uncontrolled glaucoma with intraocular pressure > or =18 mm Hg and < or =40 mm Hg on maximum tolerated medical therapy. interventions: 350-mm(2) Baerveldtglaucoma implant or trabeculectomy with mitomycin C (MMC). main outcome measures: Preoperative and postoperative evaluation of ocular motility and diplopia. RESULTS:Motility disturbances were detected in 55 patients (28%) at baseline. New-onset persistent diplopia was reported in 5 patients (5%) in the tube group and no patients in the trabeculectomy group at 1 year (P = .06). A new postoperative motility disturbance developed or worsened in 7 patients (9.9%) in the tube group and no patients in the trabeculectomy group during the first year of follow-up (P = .005). Postoperative motility disturbances were also associated with increasing age (P < .001) and right eye surgery (P = .044). CONCLUSIONS:Preoperative motility disturbances were common among patients in the TVT Study. New postoperative motility disturbances were more frequent following tube shunt surgery than trabeculectomy with MMC after 1 year of follow-up.
Authors: R Krishna; D G Godfrey; D L Budenz; E Escalona-Camaaño; S J Gedde; D S Greenfield; W Feuer; I U Scott Journal: Ophthalmology Date: 2001-03 Impact factor: 12.079
Authors: Esma Islamaj; Luc Van Vught; Caroline P Jordaan-Kuip; Koenraad A Vermeer; Teresa A Ferreira; Peter W T De Waard; Hans G Lemij; Jan-Willem M Beenakker Journal: PLoS One Date: 2022-10-20 Impact factor: 3.752
Authors: Donald L Budenz; William J Feuer; Keith Barton; Joyce Schiffman; Vital P Costa; David G Godfrey; Yvonne M Buys Journal: Am J Ophthalmol Date: 2015-11-18 Impact factor: 5.258
Authors: Swarup S Swaminathan; Alessandro A Jammal; Helen L Kornmann; Philip P Chen; William J Feuer; Felipe A Medeiros; Steven J Gedde Journal: Ophthalmology Date: 2020-03-04 Impact factor: 14.277