Literature DB >> 18454300

Investigation of emission-transmission misalignment artifacts on rubidium-82 cardiac PET with adenosine pharmacologic stress.

David M Schuster1, Raghuveer K Halkar, Fabio P Esteves, Ernest V Garcia, C David Cooke, Mushabbar A Syed, F DuBois Bowman, John R Votaw.   

Abstract

PURPOSE: This study was undertaken to determine if artifacts from misalignment of cardiac emission to transmission data is present in adenosine stress studies and if the artifact could be reproduced by intentional misalignment in normal exams. PROCEDURES: Seventy consecutive 82Rb myocardial perfusion studies were reviewed. Utilizing a quality control program, misalignment was assessed. The study was reprocessed after manual realignment to determine if the defect extent changed. Emission and transmission acquisitions in six normal studies also were intentionally misaligned.
RESULTS: Twenty of 69 rest studies (29.0%) and 17 of 69 (24.6%) stress studies demonstrated misalignment. In four patients with stress misalignment, there was a significant change in clinical interpretation. Upon intentionally misaligning six normal studies, a lateral wall defect was reproduced.
CONCLUSIONS: Emission-transmission misalignment occurs in 29.0% and 24.6% of 82Rb rest and adenosine stress studies, respectively. While there is a positive correlation of artifactual defects with misalignment, the presence and size of artifacts is variable and unpredictable at seemingly lesser degrees of misalignment.

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Year:  2008        PMID: 18454300     DOI: 10.1007/s11307-008-0139-2

Source DB:  PubMed          Journal:  Mol Imaging Biol        ISSN: 1536-1632            Impact factor:   3.488


  23 in total

1.  Outcomes and costs of positron emission tomography: comparison of intravenous adenosine and intravenous dipyridamole.

Authors:  M J Holmberg; S M Mohiuddin; D E Hilleman; B D Lucas; E C Wadibia
Journal:  Clin Ther       Date:  1997 May-Jun       Impact factor: 3.393

2.  Common artifacts in PET myocardial perfusion images due to attenuation-emission misregistration: clinical significance, causes, and solutions.

Authors:  Catalin Loghin; Stefano Sdringola; K Lance Gould
Journal:  J Nucl Med       Date:  2004-06       Impact factor: 10.057

3.  Optimal specificity of thallium-201 SPECT through recognition of imaging artifacts.

Authors:  E G DePuey; E V Garcia
Journal:  J Nucl Med       Date:  1989-04       Impact factor: 10.057

4.  Frequent diagnostic errors in cardiac PET/CT due to misregistration of CT attenuation and emission PET images: a definitive analysis of causes, consequences, and corrections.

Authors:  K Lance Gould; Tinsu Pan; Catalin Loghin; Nils P Johnson; Ashrith Guha; Stefano Sdringola
Journal:  J Nucl Med       Date:  2007-06-15       Impact factor: 10.057

5.  Quantitative same-day rest-stress technetium-99m-sestamibi SPECT: definition and validation of stress normal limits and criteria for abnormality.

Authors:  K F Van Train; J Areeda; E V Garcia; C D Cooke; J Maddahi; H Kiat; G Germano; G Silagan; R Folks; D S Berman
Journal:  J Nucl Med       Date:  1993-09       Impact factor: 10.057

6.  Simulation study of respiratory-induced errors in cardiac positron emission tomography/computed tomography.

Authors:  Gianna M Fitzpatrick; R Glenn Wells
Journal:  Med Phys       Date:  2006-08       Impact factor: 4.071

7.  Technical aspects of myocardial SPECT imaging with technetium-99m sestamibi.

Authors:  E V Garcia; C D Cooke; K F Van Train; R Folks; J Peifer; E G DePuey; J Maddahi; N Alazraki; J Galt; N Ezquerra
Journal:  Am J Cardiol       Date:  1990-10-16       Impact factor: 2.778

Review 8.  Clinical cardiac positron emission tomography: state of the art.

Authors:  K L Gould
Journal:  Circulation       Date:  1991-09       Impact factor: 29.690

Review 9.  Cardiac positron emission tomography and the role of adenosine pharmacologic stress.

Authors:  Timothy M Bateman
Journal:  Am J Cardiol       Date:  2004-07-22       Impact factor: 2.778

10.  Minimizing artifacts resulting from respiratory and cardiac motion by optimization of the transmission scan in cardiac PET/CT.

Authors:  Jonathon A Nye; Fabio Esteves; John R Votaw
Journal:  Med Phys       Date:  2007-06       Impact factor: 4.071

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  1 in total

1.  Is metal artefact reduction mandatory in cardiac PET/CT imaging in the presence of pacemaker and implantable cardioverter defibrillator leads?

Authors:  Pardis Ghafarian; S M R Aghamiri; Mohammad R Ay; Arman Rahmim; Thomas H Schindler; Osman Ratib; Habib Zaidi
Journal:  Eur J Nucl Med Mol Imaging       Date:  2010-10-20       Impact factor: 9.236

  1 in total

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