Literature DB >> 17661031

Performance of the new generation of whole-body PET/CT scanners: Discovery STE and Discovery VCT.

M Teräs1, T Tolvanen, J J Johansson, J J Williams, J Knuuti.   

Abstract

PURPOSE: The new GE Discovery STE and Discovery VCT respectively combine 16-slice and 64-slice CT with PET. The PET scanner has a new BGO detector block of 8 x 6 matrix (6.3 x 4.7 x 30 mm(3)). The aim of this study was to test the performance of the new scanner.
METHODS: The PET performance evaluation was done using NEMA methodology. Owing to improved front-end electronics, the system was tested with different energy window and coincidence timing settings.
RESULTS: Transaxial resolution FWHM for 2D(3D) mode at 1 cm offset from the centre of the field of view (R1) was 4.87 mm (5.12 mm) and at 10 cm off centre (R10) radially 5.70 mm (5.89 mm) and tangentially 5.84 mm (5.47 mm). The axial resolutions were 4.4 mm (5.18 mm) (R1) and 5.99 mm (5.86 mm) (R10). The sensitivities were 2.3 cps/kBq (8.8 cps/kBq) (R0, centre of field of view) and 2.3 cps/kBq (8.9 cps/kBq) (R10). The system scatter fraction was 21.4% in 2D at an energy of 375 keV (33.9% in 3D mode at a higher energy of 425 keV). Peak noise equivalent count rates (k=1) were 84.9 kcps at 43.9 kBq/ml (2D) and 67.6 kcps at 12.1 kBq/ml (3D). In image quality measurement the hot sphere to background contrast with 10- to 22-mm diameter spheres varied from 14% to 68%, being slightly better in 3D than in 2D mode. Cold sphere contrast was 67% in 2D and 59% in 3D mode.
CONCLUSION: GE's new STE and VCT PET/CT systems have improved spatial resolution without loss in sensitivity. When compared with the LYSO crystal-based GE Discovery RX, the resolution and scatter fraction are comparable, the count rate capability is lower but the sensitivity is higher.

Mesh:

Year:  2007        PMID: 17661031     DOI: 10.1007/s00259-007-0493-3

Source DB:  PubMed          Journal:  Eur J Nucl Med Mol Imaging        ISSN: 1619-7070            Impact factor:   9.236


  13 in total

Review 1.  From PET detectors to PET scanners.

Authors:  John L Humm; Anatoly Rosenfeld; Alberto Del Guerra
Journal:  Eur J Nucl Med Mol Imaging       Date:  2003-10-02       Impact factor: 9.236

2.  Against: Is LSO the future of PET?

Authors:  Joel S Karp
Journal:  Eur J Nucl Med Mol Imaging       Date:  2002-11       Impact factor: 9.236

3.  PET performance measurements using the NEMA NU 2-2001 standard.

Authors:  Margaret E Daube-Witherspoon; Joel S Karp; Michael E Casey; Frank P DiFilippo; Horace Hines; Gerd Muehllehner; Vilim Simcic; Charles W Stearns; Lars-Eric Adam; Steve Kohlmyer; Vesna Sossi
Journal:  J Nucl Med       Date:  2002-10       Impact factor: 10.057

4.  PET performance measurements for an LSO-based combined PET/CT scanner using the National Electrical Manufacturers Association NU 2-2001 standard.

Authors:  Yusuf E Erdi; Sadek A Nehmeh; Tim Mulnix; John L Humm; Charles C Watson
Journal:  J Nucl Med       Date:  2004-05       Impact factor: 10.057

5.  Performance characteristics of a newly developed PET/CT scanner using NEMA standards in 2D and 3D modes.

Authors:  Osama Mawlawi; Donald A Podoloff; Steve Kohlmyer; John J Williams; Charles W Stearns; Randall F Culp; Homer Macapinlac
Journal:  J Nucl Med       Date:  2004-10       Impact factor: 10.057

6.  Performance characteristics obtained for a new 3-dimensional lutetium oxyorthosilicate-based whole-body PET/CT scanner with the National Electrical Manufacturers Association NU 2-2001 standard.

Authors:  Marco Brambilla; Chiara Secco; Marco Dominietto; Roberta Matheoud; Gianmauro Sacchetti; Eugenio Inglese
Journal:  J Nucl Med       Date:  2005-12       Impact factor: 10.057

7.  Performance standards in positron emission tomography.

Authors:  J S Karp; M E Daube-Witherspoon; E J Hoffman; T K Lewellen; J M Links; W H Wong; R D Hichwa; M E Casey; J G Colsher; R E Hitchens
Journal:  J Nucl Med       Date:  1991-12       Impact factor: 10.057

8.  Performance evaluation of the new whole-body PET/CT scanner: Discovery ST.

Authors:  Valentino Bettinardi; Massimo Danna; Annarita Savi; Michela Lecchi; Isabella Castiglioni; Maria Carla Gilardi; Helmut Bammer; Giovanni Lucignani; Ferruccio Fazio
Journal:  Eur J Nucl Med Mol Imaging       Date:  2004-02-10       Impact factor: 9.236

9.  Performance characteristics of a whole-body PET scanner.

Authors:  T R DeGrado; T G Turkington; J J Williams; C W Stearns; J M Hoffman; R E Coleman
Journal:  J Nucl Med       Date:  1994-08       Impact factor: 10.057

10.  Performance of Philips Gemini TF PET/CT scanner with special consideration for its time-of-flight imaging capabilities.

Authors:  Suleman Surti; Austin Kuhn; Matthew E Werner; Amy E Perkins; Jeffrey Kolthammer; Joel S Karp
Journal:  J Nucl Med       Date:  2007-03       Impact factor: 10.057

View more
  44 in total

Review 1.  PET/MRI hybrid imaging: devices and initial results.

Authors:  Bernd J Pichler; Martin S Judenhofer; Hans F Wehrl
Journal:  Eur Radiol       Date:  2008-03-21       Impact factor: 5.315

2.  Assessment of patient selection criteria for quantitative imaging with respiratory-gated positron emission tomography.

Authors:  Stephen R Bowen; Larry A Pierce; Adam M Alessio; Chi Liu; Scott D Wollenweber; Charles W Stearns; Paul E Kinahan
Journal:  J Med Imaging (Bellingham)       Date:  2014-09-24

3.  Dual gated PET/CT imaging of small targets of the heart: method description and testing with a dynamic heart phantom.

Authors:  Tommi Kokki; Hannu T Sipilä; Mika Teräs; Tommi Noponen; Nicolas Durand-Schaefer; Riku Klén; Juhani Knuuti
Journal:  J Nucl Cardiol       Date:  2010 Jan-Feb       Impact factor: 5.952

Review 4.  Precision and accuracy of clinical quantification of myocardial blood flow by dynamic PET: A technical perspective.

Authors:  Jonathan B Moody; Benjamin C Lee; James R Corbett; Edward P Ficaro; Venkatesh L Murthy
Journal:  J Nucl Cardiol       Date:  2015-04-14       Impact factor: 5.952

5.  Quantitative and qualitative evaluation of sequential PET/MRI using a newly developed mobile PET system for brain imaging.

Authors:  Mizue Suzuki; Yasutaka Fushimi; Tomohisa Okada; Takuya Hinoda; Ryusuke Nakamoto; Yoshiki Arakawa; Nobukatsu Sawamoto; Kaori Togashi; Yuji Nakamoto
Journal:  Jpn J Radiol       Date:  2021-02-28       Impact factor: 2.374

6.  Correlation of 18F-FDG PET/CT assessments with disease activity and markers of inflammation in patients with early rheumatoid arthritis following the initiation of combination therapy with triple oral antirheumatic drugs.

Authors:  Anne Roivainen; Sannamari Hautaniemi; Timo Möttönen; Pirjo Nuutila; Vesa Oikonen; Riitta Parkkola; Luminita Pricop; Rudyard Ress; Nicholas Seneca; Marko Seppänen; Timo Yli-Kerttula
Journal:  Eur J Nucl Med Mol Imaging       Date:  2012-11-15       Impact factor: 9.236

7.  Impact of third-line treatment with irinotecan plus cetuximab on non-tumor standardized uptake values in patients with metastatic colorectal cancer.

Authors:  Kim Francis Andersen; Kristin Skougaard; Anne Lerberg Nielsen; Helle Westergren Hendel
Journal:  Oncol Lett       Date:  2012-04-18       Impact factor: 2.967

8.  PET Probe-Guided Surgery in Patients with Breast Cancer: Proposal for a Methodological Approach.

Authors:  Paolo Orsaria; Agostino Chiaravalloti; Alessandro Fiorentini; Chiara Pistolese; Gianluca Vanni; Alessandra Vittoria Granai; Dimitrios Varvaras; Roberta Danieli; Orazio Schillaci; Giuseppe Petrella; Oreste Claudio Buonomo
Journal:  In Vivo       Date:  2017-01-02       Impact factor: 2.155

9.  Validation of 18F-FDG-PET Single-Subject Optimized SPM Procedure with Different PET Scanners.

Authors:  Luca Presotto; Tommaso Ballarini; Silvia Paola Caminiti; Valentino Bettinardi; Luigi Gianolli; Daniela Perani
Journal:  Neuroinformatics       Date:  2017-04

10.  Validation of [18F]fluorodeoxyglucose and positron emission tomography (PET) for the measurement of intestinal metabolism in pigs, and evidence of intestinal insulin resistance in patients with morbid obesity.

Authors:  H Honka; J Mäkinen; J C Hannukainen; M Tarkia; V Oikonen; M Teräs; V Fagerholm; T Ishizu; A Saraste; C Stark; T Vähäsilta; P Salminen; A Kirjavainen; M Soinio; A Gastaldelli; J Knuuti; P Iozzo; P Nuutila
Journal:  Diabetologia       Date:  2013-01-20       Impact factor: 10.122

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.