Literature DB >> 17639386

Polyetheretherketone (PEEK) cage filled with cancellous allograft in anterior cervical discectomy and fusion.

Jen-Chung Liao1, Chi-Chien Niu, Wen-Jer Chen, Lih-Huei Chen.   

Abstract

From July 2004 to June 2005, 19 patients with 25 discs underwent anterior cervical discectomy and interbody fusion (ACDF) in which polyetheretherketone (PEEK) cages were filled with freeze-dried cancellous allograft bone. This kind of bone graft was made from femoral condyle that was harvested during total knee arthroplasty. Patient age at surgery was 52.9 (28-68) years. All patients were followed up at least 1 year. We measured the height of the disc and segmental sagittal angulation by pre-operative and post-operative radiographs. CT scan of the cervical spine at 1 year was used to evaluate fusion rates. Odom's criteria were used to assess the clinical outcome. All interbody disc spaces achieved successful union at 1-year follow-up. The use of a PEEK cage was found to increase the height of the disc immediately after surgery (5.0 mm pre-operatively, 7.3 mm immediately post-operatively). The final disc height was 6.2 mm, and the collapse of the disc height was 1.1 mm. The segmental lordosis also increased after surgery (2.0 degrees pre-operatively, 6.6 degrees immediately post-operatively), but the mean loss of lordosis correction was 3.3 degrees at final follow-up. Seventy-four percent of patients (14/19) exhibited excellent/good clinical outcomes. Analysis of the results indicated the cancellous allograft bone-filled PEEK cage used in ACDF is a good choice for patients with cervical disc disease, and avoids the complications of harvesting iliac autograft.

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Year:  2007        PMID: 17639386      PMCID: PMC2551716          DOI: 10.1007/s00264-007-0378-x

Source DB:  PubMed          Journal:  Int Orthop        ISSN: 0341-2695            Impact factor:   3.075


  19 in total

1.  The treatment of certain cervical-spine disorders by anterior removal of the intervertebral disc and interbody fusion.

Authors:  G W SMITH; R A ROBINSON
Journal:  J Bone Joint Surg Am       Date:  1958-06       Impact factor: 5.284

2.  Cervical disk lesions.

Authors:  G L ODOM; W FINNEY; B WOODHALL
Journal:  J Am Med Assoc       Date:  1958-01-04

3.  Polyetheretherketone as a biomaterial for spinal applications.

Authors:  Jeffrey M Toth; Mei Wang; Bradley T Estes; Jeffrey L Scifert; Howard B Seim; A Simon Turner
Journal:  Biomaterials       Date:  2005-08-22       Impact factor: 12.479

4.  Anterior cervical interbody fusion with radiolucent carbon fiber cages: clinical and radiological results.

Authors:  Ibo van der Haven; Piet J M van Loon; Ronald H M A Bartels; Job L C van Susante
Journal:  Acta Orthop Belg       Date:  2005-10       Impact factor: 0.500

5.  Outcome analyses of interbody titanium cage fusion used in the anterior discectomy for cervical degenerative disc disease.

Authors:  Shiuh-Lin Hwang; Yan-Fen Hwang; Ann-Shung Lieu; Chih-Lung Lin; Tai-Hung Kuo; Yu-Feng Su; Shen-Long Howng; Kung-Shing Lee
Journal:  J Spinal Disord Tech       Date:  2005-08

6.  Trapezoidal titanium cage in anterior cervical interbody fusion: a clinical experience.

Authors:  Chi-Chien Niu; Lih-Huei Chen; Po-Liang Lai; Tsai-Sheng Fu; Wen-Jer Chen
Journal:  Chang Gung Med J       Date:  2005-04

7.  Complications of iliac crest bone graft harvesting.

Authors:  E D Arrington; W J Smith; H G Chambers; A L Bucknell; N A Davino
Journal:  Clin Orthop Relat Res       Date:  1996-08       Impact factor: 4.176

8.  Maintenance of interbody space in one- and two-level anterior cervical interbody fusion: comparison of the effectiveness of autograft, allograft, and cage.

Authors:  Feng-Chen Kao; Chi-Chien Niu; Lih-Huei Chen; Po-Liang Lai; Wen-Jer Chen
Journal:  Clin Orthop Relat Res       Date:  2005-01       Impact factor: 4.176

9.  Anterior cervical discectomy and fusion involving a polyetheretherketone spacer and bone morphogenetic protein.

Authors:  Maxwell Boakye; Praveen V Mummaneni; Mark Garrett; Gerald Rodts; Regis Haid
Journal:  J Neurosurg Spine       Date:  2005-05

10.  An early comparative analysis of the use of fibular allograft versus autologous iliac crest graft for interbody fusion after anterior cervical discectomy.

Authors:  W F Young; R H Rosenwasser
Journal:  Spine (Phila Pa 1976)       Date:  1993-07       Impact factor: 3.468

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  29 in total

1.  A Prospective Study of the Functional Outcome of Anterior Cervical Discectomy With Fusion in Single Level Degenerative Cervical Disc Prolapse.

Authors:  Mayur M Kamani; Arjun Ballal; Vikram Shetty; H Ravindranath Rai; Deepak Hegde
Journal:  J Clin Diagn Res       Date:  2016-05-01

2.  Evaluation of bony fusion after anterior cervical discectomy: a systematic literature review.

Authors:  I Noordhoek; M T Koning; C L A Vleggeert-Lankamp
Journal:  Eur Spine J       Date:  2018-11-17       Impact factor: 3.134

3.  Evolution of Design of Interbody Cages for Anterior Lumbar Interbody Fusion.

Authors:  Kevin Phan; Ralph J Mobbs
Journal:  Orthop Surg       Date:  2016-08       Impact factor: 2.071

4.  Plate augmentation in anterior cervical discectomy and fusion with cage for degenerative cervical spinal disorders.

Authors:  Kyung-Jin Song; Cyrus E Taghavi; Margaret S Hsu; Kwang-Bok Lee; Gyu-Hyung Kim; Ji-Hoon Song
Journal:  Eur Spine J       Date:  2010-02-21       Impact factor: 3.134

5.  Efficacy of PEEK cages and plate augmentation in three-level anterior cervical fusion of elderly patients.

Authors:  Kyung Jin Song; Gyu Hyung Kim; Byeong Yeol Choi
Journal:  Clin Orthop Surg       Date:  2011-02-15

6.  A prospective randomized comparison of PEEK cage containing calcium sulphate or demineralized bone matrix with autograft in anterior cervical interbody fusion.

Authors:  Youzhuan Xie; Hua Li; Junjie Yuan; Lingjie Fu; Jianwei Yang; Pu Zhang
Journal:  Int Orthop       Date:  2014-11-30       Impact factor: 3.075

Review 7.  Biomaterial strategies for engineering implants for enhanced osseointegration and bone repair.

Authors:  Rachit Agarwal; Andrés J García
Journal:  Adv Drug Deliv Rev       Date:  2015-04-08       Impact factor: 15.470

8.  Comparison between anterior cervical discectomy fusion and cervical corpectomy fusion using titanium cages for reconstruction: analysis of outcome and long-term follow-up.

Authors:  Juan S Uribe; Jaypal Reddy Sangala; Edward A M Duckworth; Fernando L Vale
Journal:  Eur Spine J       Date:  2009-02-12       Impact factor: 3.134

9.  Polyetheretherketone (PEEK) cage filled with bone morphogenic protein and demineralised bone matrix in anterior cervical discectomy and fusion.

Authors:  Rob D Dickerman; Ashley S Reynolds; Brent Morgan
Journal:  Int Orthop       Date:  2007-08-28       Impact factor: 3.075

Review 10.  Polyurethane on titanium unconstrained disc arthroplasty versus anterior discectomy and fusion for the treatment of cervical disc disease: a review of level I-II randomized clinical trials including clinical outcomes.

Authors:  María Aragonés; Eduardo Hevia; Carlos Barrios
Journal:  Eur Spine J       Date:  2015-09-12       Impact factor: 3.134

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