Literature DB >> 17348706

Guttiferones K and L, antiproliferative compounds of Rheedia calcicola from the Madagascar rain forest.

Shugeng Cao1, Peggy J Brodie, James S Miller, Fidy Ratovoson, Chris Birkinshaw, Sennen Randrianasolo, Etienne Rakotobe, Vincent E Rasamison, David G I Kingston.   

Abstract

Bioassay-guided fractionation of the ethanol extract obtained from the fruits of Rheedia calcicola led to the isolation of two new guttiferone analogues, guttiferones K (1) and L (16-hydroxyguttiferone K) (2). The structures of 1 and 2 were established on the basis of extensive interpretation of one- and two-dimensional NMR spectroscopic data. Both compounds were tested for their antiproliferative activity against the A2780 human ovarian cancer cell line.

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Year:  2007        PMID： 17348706      PMCID： PMC2464366          DOI： 10.1021/np070004i

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  13 in total

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9.  Radiation survival parameters of antineoplastic drug-sensitive and -resistant human ovarian cancer cell lines and their modification by buthionine sulfoximine.

Authors:  K G Louie; B C Behrens; T J Kinsella; T C Hamilton; K R Grotzinger; W M McKoy; M A Winker; R F Ozols
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Journal:  Fitoterapia       Date:  2004-06       Impact factor: 2.882
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  6 in total

1.  Antiproliferative cardenolides of an Elaeodendron sp. from the Madagascar rain forest(1).

Authors:  Shugeng Cao; Peggy J Brodie; James S Miller; Fidy Ratovoson; Martin W Callmander; Sennen Randrianasolo; Etienne Rakotobe; Vincent E Rasamison; Edward M Suh; Karen TenDyke; David G I Kingston
Journal:  J Nat Prod       Date:  2007-06-05       Impact factor: 4.050

2.  An antiproliferative xanthone of Symphonia pauciflora from the Madagascar rainforest.

Authors:  Ende Pana; Shugeng Cao; Peggy J Brodie; James S Miller; Rolland Rakotodrajaona; Fidy Ratovoson; Chris Birkinshaw; Rabodo Andriantsiferana; Vincent E Rasamison; David G I Kingston
Journal:  Nat Prod Commun       Date:  2010-05       Impact factor: 0.986

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Journal:  Chem Commun (Camb)       Date:  2010-07-07       Impact factor: 6.222

4.  Antiproliferative compounds of Artabotrys madagascariensis from the Madagascar rainforest.

Authors:  Brian T Murphy; Shugeng Cao; Peggy J Brodie; James S Miller; Fidy Ratovoson; Chris Birkinshaw; Etienne Rakotobe; Vincent E Rasamison; Karen Tendyke; Edward M Suh; David G I Kingston
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Authors:  Shugeng Cao; David G I Kingston
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  6 in total

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