Literature DB >> 17061307

On the acceptor substrate of C-glycosyltransferase UrdGT2: three prejadomycin C-Glycosides from an engineered mutant of Streptomyces globisporus 1912 DeltalndE(urdGT2).

Irfan Baig1, Madan Kharel, Anton Kobylyanskyy, Lili Zhu, Yuriy Rebets, Bohdan Ostash, Andriy Luzhetskyy, Andreas Bechthold, Victor A Fedorenko, Jürgen Rohr.   

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Year:  2006        PMID： 17061307      PMCID： PMC2881212          DOI： 10.1002/anie.200603176

Source DB:  PubMed          Journal:  Angew Chem Int Ed Engl        ISSN： 1433-7851            Impact factor:   15.336


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  23 in total

1.  The NDP-sugar co-substrate concentration and the enzyme expression level influence the substrate specificity of glycosyltransferases: cloning and characterization of deoxysugar biosynthetic genes of the urdamycin biosynthetic gene cluster.

Authors:  D Hoffmeister; K Ichinose; S Domann; B Faust; A Trefzer; G Dräger; A Kirschning; C Fischer; E Künzel; D Bearden; J Rohr; A Bechthold
Journal:  Chem Biol       Date:  2000-11

2.  Urdamycin L: a novel metabolic shunt product that provides evidence for the role of the urdM gene in the urdamycin A biosynthetic pathway of Streptomyces fradiae TU 2717.

Authors:  Uwe Rix; Lily L Remsing; Dirk Hoffmeister; Andreas Bechthold; Jürgen Rohr
Journal:  Chembiochem       Date:  2003-01-03       Impact factor: 3.164

3.  Function of lanGT3, a glycosyltransferase gene involved in landomycin A biosynthesis.

Authors:  Andriy Luzhetskyy; Tao Liu; Marta Fedoryshyn; Bohdan Ostash; Viktor Fedorenko; Jürgen Rohr; Andreas Bechthold
Journal:  Chembiochem       Date:  2004-11-05       Impact factor: 3.164

4.  Generation of novel landomycins M and O through targeted gene disruption.

Authors:  Andriy Luzhetskyy; Lili Zhu; Miranda Gibson; Marta Fedoryshyn; Clemens Dürr; Carsten Hofmann; Dirk Hoffmeister; Bohdan Ostash; Cynthia Mattingly; Val Adams; Victor Fedorenko; Jürgen Rohr; Andreas Bechthold
Journal:  Chembiochem       Date:  2005-04       Impact factor: 3.164

5.  Cloning and characterization of a gene cluster from Streptomyces cyanogenus S136 probably involved in landomycin biosynthesis.

Authors:  L Westrich; S Domann; B Faust; D Bedford; D A Hopwood; A Bechthold
Journal:  FEMS Microbiol Lett       Date:  1999-01-15       Impact factor: 2.742

6.  Landomycin A inhibits DNA synthesis and G1/S cell cycle progression.

Authors:  R T Crow; B Rosenbaum; R Smith; Y Guo; K S Ramos; G A Sulikowski
Journal:  Bioorg Med Chem Lett       Date:  1999-06-21       Impact factor: 2.823

Review 7.  Glycosyltransferases involved in the biosynthesis of biologically active natural products that contain oligosaccharides.

Authors:  Andriy Luzhetskyy; Andreas Vente; Andreas Bechthold
Journal:  Mol Biosyst       Date:  2005-06-23

8.  Engineered urdamycin glycosyltransferases are broadened and altered in substrate specificity.

Authors:  Dirk Hoffmeister; Barrie Wilkinson; Graham Foster; Philip J Sidebottom; Koji Ichinose; Andreas Bechthold
Journal:  Chem Biol       Date:  2002-03

9.  Cloning and characterization of a polyketide synthase gene from Streptomyces fradiae Tü2717, which carries the genes for biosynthesis of the angucycline antibiotic urdamycin A and a gene probably involved in its oxygenation.

Authors:  H Decker; S Haag
Journal:  J Bacteriol       Date:  1995-11       Impact factor: 3.490

10.  Urdamycins, new angucycline antibiotics from Streptomyces fradiae. IV. Biosynthetic studies of urdamycins A-D.

Authors:  J Rohr; J M Beale; H G Floss
Journal:  J Antibiot (Tokyo)       Date:  1989-07       Impact factor: 2.649
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  10 in total

1.  OleD Loki as a Catalyst for Tertiary Amine and Hydroxamate Glycosylation.

Authors:  Ryan R Hughes; Khaled A Shaaban; Jianjun Zhang; Hongnan Cao; George N Phillips; Jon S Thorson
Journal:  Chembiochem       Date:  2017-01-09       Impact factor: 3.164

2.  Structural characterization of O- and C-glycosylating variants of the landomycin glycosyltransferase LanGT2.

Authors:  Heng Keat Tam; Johannes Härle; Stefan Gerhardt; Jürgen Rohr; Guojun Wang; Jon S Thorson; Aurélien Bigot; Monika Lutterbeck; Wolfgang Seiche; Bernhard Breit; Andreas Bechthold; Oliver Einsle
Journal:  Angew Chem Int Ed Engl       Date:  2015-01-07       Impact factor: 15.336

3.  Cloning and characterization of the ravidomycin and chrysomycin biosynthetic gene clusters.

Authors:  Madan K Kharel; S Eric Nybo; Micah D Shepherd; Jürgen Rohr
Journal:  Chembiochem       Date:  2010-03-01       Impact factor: 3.164

4.  Properties of lanK-based regulatory circuit involved in landomycin biosynthesis in Streptomyces cyanogenus S136.

Authors:  B Ostash; I Ostash; L Zhu; M K Kharel; A Luzhetskiĭ; A Bechthold; S Walker; J Rohr; V Fedorenko
Journal:  Genetika       Date:  2010-05

Review 5.  Delineation of gilvocarcin, jadomycin, and landomycin pathways through combinatorial biosynthetic enzymology.

Authors:  Madan K Kharel; Jürgen Rohr
Journal:  Curr Opin Chem Biol       Date:  2012-03-30       Impact factor: 8.822

6.  Generation of new landomycins with altered saccharide patterns through over-expression of the glycosyltransferase gene lanGT3 in the biosynthetic gene cluster of landomycin A in Streptomyces cyanogenus S-136.

Authors:  Lili Zhu; Andriy Luzhetskyy; Martha Luzhetska; Cynthia Mattingly; Val Adams; Andreas Bechthold; Jürgen Rohr
Journal:  Chembiochem       Date:  2007-01-02       Impact factor: 3.164

7.  Moromycins A and B, isolation and structure elucidation of C-glycosylangucycline-type antibiotics from Streptomyces sp. KY002.

Authors:  Mohamed S Abdelfattah; Madan Kumar Kharel; John Andrew Hitron; Irfan Baig; Jürgen Rohr
Journal:  J Nat Prod       Date:  2008-07-31       Impact factor: 4.050

8.  Two Cooperative Glycosyltransferases Are Responsible for the Sugar Diversity of Saquayamycins Isolated from Streptomyces sp. KY 40-1.

Authors:  Shaimaa M Salem; Stevi Weidenbach; Jürgen Rohr
Journal:  ACS Chem Biol       Date:  2017-09-13       Impact factor: 5.100

9.  OleD Loki as a Catalyst for Hydroxamate Glycosylation.

Authors:  Ryan R Hughes; Khaled A Shaaban; Larissa V Ponomareva; Jamie Horn; Chunhui Zhang; Chang-Guo Zhan; S Randal Voss; Markos Leggas; Jon S Thorson
Journal:  Chembiochem       Date:  2019-11-26       Impact factor: 3.164

Review 10.  Leloir Glycosyltransferases in Applied Biocatalysis: A Multidisciplinary Approach.

Authors:  Luuk Mestrom; Marta Przypis; Daria Kowalczykiewicz; André Pollender; Antje Kumpf; Stefan R Marsden; Isabel Bento; Andrzej B Jarzębski; Katarzyna Szymańska; Arkadiusz Chruściel; Dirk Tischler; Rob Schoevaart; Ulf Hanefeld; Peter-Leon Hagedoorn
Journal:  Int J Mol Sci       Date:  2019-10-23       Impact factor: 5.923
  10 in total

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