Literature DB >> 17023189

Femoroplasty--augmentation of the proximal femur with a composite bone cement--feasibility, biomechanical properties and osteosynthesis potential.

J Beckmann1, S J Ferguson, M Gebauer, C Luering, B Gasser, P Heini.   

Abstract

BACKGROUND: Analogous to vertebroplasty, cement-augmentation of the proximal femur ("femoroplasty") could reinforce osteoporotic bones. This study was to evaluate (i) the feasibility of femoroplasty with a composite cement (Cortoss), (ii) its influence on femoral strength by mechanical testing and (iii) the feasibility of stable osteosynthesis of the augmented fractured bones.
METHODS: Nine human cadaveric femora were augmented with a composite bone cement, the surface heat generation monitored, and then tested biomechanically against their native contralateral control to determine fracture strength. Subsequently, thirteen reinforced and fractured femora were osteosynthetized by different implants and tested against their osteosynthetisized, non-augmented contralateral control.
FINDINGS: Cement could be injected easily, with a moderate temperature rise. A positive correlation between BMD and fracture load and a significant increase in fracture load (+43%) of the augmented femora compared to their native controls (6324 N and 4430 N, respectively) as well as a significant increase in energy-to-failure (+187%, 86 N m and 30 N m, respectively) was found. Osteosynthesis was possible in cement-augmented femora. Osteosynthetisized femora showed equivalent strength to the intact controls.
INTERPRETATION: Augmentation of the proximal femur with composite bone cement could be of use in prophylaxis of fractures in osteoporotic femurs. Osteosynthesis of the fractured augmented bones is a challenging procedure but has a good chance to restore strength.

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Year:  2006        PMID: 17023189     DOI: 10.1016/j.medengphy.2006.08.006

Source DB:  PubMed          Journal:  Med Eng Phys        ISSN: 1350-4533            Impact factor:   2.242


  23 in total

1.  Subject-specific planning of femoroplasty: a combined evolutionary optimization and particle diffusion model approach.

Authors:  Ehsan Basafa; Mehran Armand
Journal:  J Biomech       Date:  2014-05-14       Impact factor: 2.712

Review 2.  Prophylactic augmentation of the osteoporotic proximal femur-mission impossible?

Authors:  Peter Varga; Ladina Hofmann-Fliri; Michael Blauth; Markus Windolf
Journal:  Bonekey Rep       Date:  2016-12-07

3.  Bone texture analysis of human femurs using a new device (BMA™) improves failure load prediction.

Authors:  S Kolta; S Paratte; T Amphoux; S Persohn; S Campana; W Skalli; S Paternotte; J-N Argenson; J-M Bouler; O Gagey; C Roux
Journal:  Osteoporos Int       Date:  2011-06-09       Impact factor: 4.507

4.  Osteosynthetic improvement of osteoporotic bone: prevention surgery.

Authors:  Sandro Giannini; Deianira Luciani; Eugenio Chiarello; Matteo Cadossi; Giuseppe Tedesco; Martha Hoque; Saverio Gnudi
Journal:  Clin Cases Miner Bone Metab       Date:  2011-01

5.  Subject-specific planning of femoroplasty: an experimental verification study.

Authors:  Ehsan Basafa; Ryan J Murphy; Yoshito Otake; Michael D Kutzer; Stephen M Belkoff; Simon C Mears; Mehran Armand
Journal:  J Biomech       Date:  2014-11-12       Impact factor: 2.712

6.  Significance of preoperative planning for prophylactic augmentation of osteoporotic hip: A computational modeling study.

Authors:  Amirhossein Farvardin; Ehsan Basafa; Mahsan Bakhtiarinejad; Mehran Armand
Journal:  J Biomech       Date:  2019-07-19       Impact factor: 2.712

7.  Patient-specific finite element modeling for femoral bone augmentation.

Authors:  Ehsan Basafa; Robert S Armiger; Michael D Kutzer; Stephen M Belkoff; Simon C Mears; Mehran Armand
Journal:  Med Eng Phys       Date:  2013-02-01       Impact factor: 2.242

Review 8.  Surgical prevention of femoral neck fractures in elderly osteoporotic patients. A literature review.

Authors:  Eugenio Chiarello; Giuseppe Tedesco; Matteo Cadossi; Paola Capra; Silvio Terrando; Andrea Miti; Sandro Giannini
Journal:  Clin Cases Miner Bone Metab       Date:  2016-05-11

9.  The effect of cement placement on augmentation of the osteoporotic proximal femur.

Authors:  Edward G Sutter; Simon J Wall; Simon C Mears; Stephen M Belkoff
Journal:  Geriatr Orthop Surg Rehabil       Date:  2010-09

10.  Anatomical variance in acetabular anteversion does not predict hip fracture patterns in the elderly: a retrospective study in 135 patients.

Authors:  Megan Y Kamath; Nathan W Coleman; Stephen M Belkoff; Simon C Mears
Journal:  Geriatr Orthop Surg Rehabil       Date:  2011-03
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