PURPOSE: Global and regional left ventricular (LV) function are important indicators of the cardiac status in patients with coronary artery disease (CAD). Therapy and prognosis are to a large extent dependent on LV function. Multi-slice computed tomography (MSCT) has already earned its place as an imaging modality for non-invasive assessment of the coronary arteries, but since retrospective gating to the patient's ECG is performed, information on LV function can be derived. METHODS: In 49 patients with known or suspected CAD, coronary angiography with MSCT imaging was performed, in addition to gated SPECT and 2D echocardiography. LV end-diastolic and LV end-systolic volumes and LV ejection fraction were analysed with dedicated software (CMR Analytical Software System, Medis, Leiden, The Netherlands for MSCT; gated SPECT by QGS, Cedars-Sinai Medical Center, Los Angeles, CA, USA), and by the biplane Simpson's rule for 2D echocardiography. Regional wall motion was evaluated according to a 17-segment model and a three-point score system. RESULTS: Correlations were fairly good between gated SPECT and MSCT (LVEDV: r=0.65; LVESV: r=0.63; LVEF: r=0.60), and excellent between 2D echocardiography and MSCT (LVEDV: r=0.92; LVESV: r=0.93; LVEF: r=0.80). Agreement for regional wall motion was 95% (kappa=0.66) between gated SPECT and MSCT, and 96% (kappa=0.73) between 2D echocardiography and MSCT. CONCLUSION: Global and regional LV function and LV volumes can be adequately assessed with MSCT. Correlations with 2D echocardiography are stronger than with gated SPECT.
PURPOSE: Global and regional left ventricular (LV) function are important indicators of the cardiac status in patients with coronary artery disease (CAD). Therapy and prognosis are to a large extent dependent on LV function. Multi-slice computed tomography (MSCT) has already earned its place as an imaging modality for non-invasive assessment of the coronary arteries, but since retrospective gating to the patient's ECG is performed, information on LV function can be derived. METHODS: In 49 patients with known or suspected CAD, coronary angiography with MSCT imaging was performed, in addition to gated SPECT and 2D echocardiography. LV end-diastolic and LV end-systolic volumes and LV ejection fraction were analysed with dedicated software (CMR Analytical Software System, Medis, Leiden, The Netherlands for MSCT; gated SPECT by QGS, Cedars-Sinai Medical Center, Los Angeles, CA, USA), and by the biplane Simpson's rule for 2D echocardiography. Regional wall motion was evaluated according to a 17-segment model and a three-point score system. RESULTS: Correlations were fairly good between gated SPECT and MSCT (LVEDV: r=0.65; LVESV: r=0.63; LVEF: r=0.60), and excellent between 2D echocardiography and MSCT (LVEDV: r=0.92; LVESV: r=0.93; LVEF: r=0.80). Agreement for regional wall motion was 95% (kappa=0.66) between gated SPECT and MSCT, and 96% (kappa=0.73) between 2D echocardiography and MSCT. CONCLUSION: Global and regional LV function and LV volumes can be adequately assessed with MSCT. Correlations with 2D echocardiography are stronger than with gated SPECT.
Authors: Manuel D Cerqueira; Neil J Weissman; Vasken Dilsizian; Alice K Jacobs; Sanjiv Kaul; Warren K Laskey; Dudley J Pennell; John A Rumberger; Thomas Ryan; Mario S Verani Journal: Circulation Date: 2002-01-29 Impact factor: 29.690
Authors: S Achenbach; T Giesler; D Ropers; S Ulzheimer; H Derlien; C Schulte; E Wenkel; W Moshage; W Bautz; W G Daniel; W A Kalender; U Baum Journal: Circulation Date: 2001-05-29 Impact factor: 29.690
Authors: Joanne D Schuijf; Jeroen J Bax; Liesbeth P Salm; J Wouter Jukema; Hildo J Lamb; Ernst E van der Wall; Albert de Roos Journal: Am J Cardiol Date: 2005-03-01 Impact factor: 2.778
Authors: Martijn S Dirksen; J Wouter Jukema; Jeroen J Bax; Hildo J Lamb; Eric Boersma; Joan C Tuinenburg; Jacob Geleijns; Ernst E van der Wall; Albert de Roos Journal: Am J Cardiol Date: 2005-02-15 Impact factor: 2.778
Authors: Liesbeth P Salm; Joanne D Schuijf; Albert de Roos; Hildo J Lamb; Hubert W Vliegen; J Wouter Jukema; Raoul Joemai; Ernst E van der Wall; Jeroen J Bax Journal: Eur J Echocardiogr Date: 2005-08-10
Authors: N B Schiller; H Acquatella; T A Ports; D Drew; J Goerke; H Ringertz; N H Silverman; B Brundage; E H Botvinick; R Boswell; E Carlsson; W W Parmley Journal: Circulation Date: 1979-09 Impact factor: 29.690
Authors: G Germano; H Kiat; P B Kavanagh; M Moriel; M Mazzanti; H T Su; K F Van Train; D S Berman Journal: J Nucl Med Date: 1995-11 Impact factor: 10.057
Authors: Andreas H Mahnken; Ralf Koos; Marcus Katoh; Elmar Spuentrup; Petra Busch; Joachim E Wildberger; Harald P Kühl; Rolf W Günther Journal: Eur Radiol Date: 2005-01-29 Impact factor: 5.315
Authors: Axel Kuettner; Andreas F Kopp; Stephen Schroeder; Thilo Rieger; Juergen Brunn; Christoph Meisner; Martin Heuschmid; Tobias Trabold; Christof Burgstahler; Jens Martensen; Wolfgang Schoebel; Hans-Konrad Selbmann; Claus D Claussen Journal: J Am Coll Cardiol Date: 2004-03-03 Impact factor: 24.094
Authors: Piotr J Slomka; Daniel S Berman; Yuan Xu; Paul Kavanagh; Sean W Hayes; Sharmila Dorbala; Mathews Fish; Guido Germano Journal: J Nucl Cardiol Date: 2012-01-26 Impact factor: 5.952
Authors: Brian B Ghoshhajra; Pal Maurovich-Horvat; Tust Techasith; Hector M Medina; Daniel Verdini; Manavjot S Sidhu; Ron Blankstein; Thomas J Brady; Ricardo C Cury Journal: J Cardiovasc Comput Tomogr Date: 2011-11-18
Authors: F Cademartiri; E Maffei; A Palumbo; R Malagò; F Alberghina; A Aldrovandi; V Brambilla; G Runza; L La Grutta; A Menozzi; L Vignali; G Casolo; M Midiri; N R Mollet Journal: Radiol Med Date: 2007-10-21 Impact factor: 3.469