Literature DB >> 16756269

High-resolution NMR spectroscopy of a GPCR in aligned bicelles.

Sang Ho Park1, Stefan Prytulla, Anna A De Angelis, Jonathan Miles Brown, Hans Kiefer, Stanley J Opella.   

Abstract

Solid-state NMR spectra with single-site resolution of CXCR1, a G protein-coupled receptor (GPCR), were obtained in magnetically aligned phospholipid bicelles. These results demonstrate that GPCRs in phospholipid bilayers are suitable samples for structure determination by solid-state NMR. The spectra also enable studies of drug-receptor interactions.

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Year:  2006        PMID： 16756269      PMCID： PMC3236030          DOI： 10.1021/ja0606632

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  39 in total

1.  High-resolution NMR spectroscopy of membrane proteins in aligned bicelles.

Authors:  Anna A De Angelis; Alexander A Nevzorov; Sang Ho Park; Stanley C Howell; Anthony A Mrse; Stanley J Opella
Journal:  J Am Chem Soc       Date:  2004-12-01       Impact factor: 15.419

2.  Biosynthesis and purification of a hydrophobic peptide from transmembrane domains of G-protein-coupled CB2 receptor.

Authors:  H Zheng; J Zhao; S Wang; C-M Lin; T Chen; D H Jones; C Ma; S Opella; X-Q Xie
Journal:  J Pept Res       Date:  2005-04

Review 3.  Solid-state NMR in drug design and discovery for membrane-embedded targets.

Authors:  Anthony Watts
Journal:  Nat Rev Drug Discov       Date:  2005-07       Impact factor: 84.694

4.  Magic angle spinning NMR of the protonated retinylidene Schiff base nitrogen in rhodopsin: expression of 15N-lysine- and 13C-glycine-labeled opsin in a stable cell line.

Authors:  M Eilers; P J Reeves; W Ying; H G Khorana; S O Smith
Journal:  Proc Natl Acad Sci U S A       Date:  1999-01-19       Impact factor: 11.205

5.  SPINAL modulated decoupling in high field double- and triple-resonance solid-state NMR experiments on stationary samples.

Authors:  Neeraj Sinha; Christopher V Grant; Chin H Wu; Anna A De Angelis; Stanley C Howell; Stanley J Opella
Journal:  J Magn Reson       Date:  2005-08-30       Impact factor: 2.229

6.  Solution NMR spectroscopy of the human vasopressin V2 receptor, a G protein-coupled receptor.

Authors:  Changlin Tian; Richard M Breyer; Hak Jun Kim; Murthy D Karra; David B Friedman; Anne Karpay; Charles R Sanders
Journal:  J Am Chem Soc       Date:  2005-06-08       Impact factor: 15.419

7.  Changes in interhelical hydrogen bonding upon rhodopsin activation.

Authors:  Ashish B Patel; Evan Crocker; Philip J Reeves; Elena V Getmanova; Markus Eilers; H Gobind Khorana; Steven O Smith
Journal:  J Mol Biol       Date:  2005-04-08       Impact factor: 5.469

8.  The conformation of the cytoplasmic helix 8 of the CB1 cannabinoid receptor using NMR and circular dichroism.

Authors:  Gregory Choi; Jianxin Guo; Alexandros Makriyannis
Journal:  Biochim Biophys Acta       Date:  2005-02-01

9.  Biosynthesis and NMR analysis of a 73-residue domain of a Saccharomyces cerevisiae G protein-coupled receptor.

Authors:  Racha Estephan; Jacqueline Englander; Boris Arshava; Karen L Samples; Jeffrey M Becker; Fred Naider
Journal:  Biochemistry       Date:  2005-09-06       Impact factor: 3.162

10.  Motion of carboxyl terminus of Galpha is restricted upon G protein activation. A solution NMR study using semisynthetic Galpha subunits.

Authors:  Lori L Anderson; Garland R Marshall; Evan Crocker; Steven O Smith; Thomas J Baranski
Journal:  J Biol Chem       Date:  2005-06-27       Impact factor: 5.157
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  47 in total

1.  A rapid and efficient way to obtain modified chemokines for functional and biophysical studies.

Authors:  Samantha J Allen; Damon J Hamel; Tracy M Handel
Journal:  Cytokine       Date:  2011-05-31       Impact factor: 3.861

Review 2.  Nanodiscs versus macrodiscs for NMR of membrane proteins.

Authors:  Sang Ho Park; Sabrina Berkamp; Gabriel A Cook; Michelle K Chan; Hector Viadiu; Stanley J Opella
Journal:  Biochemistry       Date:  2011-09-30       Impact factor: 3.162

Review 3.  Structure determination of membrane proteins in five easy pieces.

Authors:  Francesca M Marassi; Bibhuti B Das; George J Lu; Henry J Nothnagel; Sang Ho Park; Woo Sung Son; Ye Tian; Stanley J Opella
Journal:  Methods       Date:  2011-09-20       Impact factor: 3.608

Review 4.  Chemical shift tensor - the heart of NMR: Insights into biological aspects of proteins.

Authors:  Hazime Saitô; Isao Ando; Ayyalusamy Ramamoorthy
Journal:  Prog Nucl Magn Reson Spectrosc       Date:  2010-05-07       Impact factor: 9.795

5.  Three-dimensional experiment for solid-state NMR of aligned protein samples in high field magnets.

Authors:  Alexander A Nevzorov; Sang Ho Park; Stanley J Opella
Journal:  J Biomol NMR       Date:  2007-01-10       Impact factor: 2.835

6.  Structure determination of a membrane protein with two trans-membrane helices in aligned phospholipid bicelles by solid-state NMR spectroscopy.

Authors:  Anna A De Angelis; Stanley C Howell; Alexander A Nevzorov; Stanley J Opella
Journal:  J Am Chem Soc       Date:  2006-09-20       Impact factor: 15.419

7.  Sensitivity and resolution enhancement in solid-state NMR spectroscopy of bicelles.

Authors:  Sergey V Dvinskikh; Kazutoshi Yamamoto; Ulrich H N Dürr; Ayyalusamy Ramamoorthy
Journal:  J Magn Reson       Date:  2006-11-02       Impact factor: 2.229

Review 8.  Solution NMR of membrane proteins in bilayer mimics: small is beautiful, but sometimes bigger is better.

Authors:  Sébastien F Poget; Mark E Girvin
Journal:  Biochim Biophys Acta       Date:  2007-09-20

9.  Helix conformations in 7TM membrane proteins determined using oriented-sample solid-state NMR with multiple residue-specific 15N labeling.

Authors:  Thomas Vosegaard; Miya Kamihira-Ishijima; Anthony Watts; Niels Chr Nielsen
Journal:  Biophys J       Date:  2007-09-07       Impact factor: 4.033

10.  Combination of ¹⁵N reverse labeling and afterglow spectroscopy for assigning membrane protein spectra by magic-angle-spinning solid-state NMR: application to the multidrug resistance protein EmrE.

Authors:  James R Banigan; Anindita Gayen; Nathaniel J Traaseth
Journal:  J Biomol NMR       Date:  2013-03-29       Impact factor: 2.835
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