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Literature DB >> 16395315

More than 1 + 2 in mRNA decapping.

Abstract

Decapping of messenger RNA was thought to involve a complex of only Dcp1 and Dcp2, but new data suggest that a larger multisubunit decapping complex exists in mammals. The larger complex includes a protein that facilitates the association of the two Dcp proteins and can be recruited by specific factors that promote mRNA decay.

Entities: Gene

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Year: 2006 PMID： 16395315 PMCID： PMC1939969 DOI： 10.1038/nsmb0106-7

Source DB: PubMed Journal: Nat Struct Mol Biol ISSN： 1545-9985 Impact factor: 15.369

19 in total

1. Identification of a human decapping complex associated with hUpf proteins in nonsense-mediated decay.

Authors: Jens Lykke-Andersen
Journal: Mol Cell Biol Date: 2002-12 Impact factor: 4.272

2. Decapping and decay of messenger RNA occur in cytoplasmic processing bodies.

Authors: Ujwal Sheth; Roy Parker
Journal: Science Date: 2003-05-02 Impact factor: 47.728

Review 3. The enzymes and control of eukaryotic mRNA turnover.

Authors: Roy Parker; Haiwei Song
Journal: Nat Struct Mol Biol Date: 2004-02 Impact factor: 15.369

4. Crystal structure of Dcp1p and its functional implications in mRNA decapping.

Authors: Meipei She; Carolyn J Decker; Kumar Sundramurthy; Yuying Liu; Nan Chen; Roy Parker; Haiwei Song
Journal: Nat Struct Mol Biol Date: 2004-02-01 Impact factor: 15.369

5. Multiple processing body factors and the ARE binding protein TTP activate mRNA decapping.

Authors: Martin Fenger-Grøn; Christy Fillman; Bodil Norrild; Jens Lykke-Andersen
Journal: Mol Cell Date: 2005-12-22 Impact factor: 17.970

6. Human Dcp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structures.

Authors: Erwin van Dijk; Nicolas Cougot; Sylke Meyer; Sylvie Babajko; Elmar Wahle; Bertrand Séraphin
Journal: EMBO J Date: 2002-12-16 Impact factor: 11.598

7. AU binding proteins recruit the exosome to degrade ARE-containing mRNAs.

Authors: C Y Chen; R Gherzi; S E Ong; E L Chan; R Raijmakers; G J Pruijn; G Stoecklin; C Moroni; M Mann; M Karin
Journal: Cell Date: 2001-11-16 Impact factor: 41.582

8. Analysis of recombinant yeast decapping enzyme.

Authors: Michelle Steiger; Anne Carr-Schmid; David C Schwartz; Megerditch Kiledjian; Roy Parker
Journal: RNA Date: 2003-02 Impact factor: 4.942

9. Identification of Edc3p as an enhancer of mRNA decapping in Saccharomyces cerevisiae.

Authors: Meenakshi Kshirsagar; Roy Parker
Journal: Genetics Date: 2004-02 Impact factor: 4.562

10. The hDcp2 protein is a mammalian mRNA decapping enzyme.

Authors: Zuoren Wang; Xinfu Jiao; Anne Carr-Schmid; Megerditch Kiledjian
Journal: Proc Natl Acad Sci U S A Date: 2002-09-06 Impact factor: 11.205

7 in total

1. The C-terminal region of Ge-1 presents conserved structural features required for P-body localization.

Authors: Martin Jinek; Ana Eulalio; Andreas Lingel; Sigrun Helms; Elena Conti; Elisa Izaurralde
Journal: RNA Date: 2008-08-28 Impact factor: 4.942

2. DCP1 forms asymmetric trimers to assemble into active mRNA decapping complexes in metazoa.

Authors: Felix Tritschler; Joerg E Braun; Carina Motz; Catia Igreja; Gabrielle Haas; Vincent Truffault; Elisa Izaurralde; Oliver Weichenrieder
Journal: Proc Natl Acad Sci U S A Date: 2009-12-04 Impact factor: 11.205

3. mRNA decapping enzyme 1a (Dcp1a)-induced translational arrest through protein kinase R (PKR) activation requires the N-terminal enabled vasodilator-stimulated protein homology 1 (EVH1) domain.

Authors: Jonathan D Dougherty; Lucas C Reineke; Richard E Lloyd
Journal: J Biol Chem Date: 2013-12-31 Impact factor: 5.157