RATIONALE AND OBJECTIVES: To compare trabecular bone structure measures obtained in magnetic resonance images of the distal radius and the calcaneus as well as computed tomographic images of the spine versus bone mineral density (BMD) of the spine and the calcaneus in the prediction of osteoporotic spine fracture status. MATERIAL AND METHODS: High-resolution magnetic resonance images of the calcaneus and the distal radius and thin-section computed tomographic images of thoracic and lumbar vertebrae were obtained from 74 cadavers. Structure analysis was performed using parameters analogous to standard histomorphometry. BMD of the spine was determined by using quantitative computed tomography and of the calcaneus by using dual x-ray absorptiometry. Spine radiographs of these cadavers were assessed concerning vertebral deformities. RESULTS: The diagnostic performance in differentiating fracture and nonfracture subjects was highest for structure parameters in the spine and slightly lower for these parameters in the distal radius and for BMD of the spine. CONCLUSION: In this study structure parameters in the spine were best suited to predict the osteoporotic fracture status of the spine.
RATIONALE AND OBJECTIVES: To compare trabecular bone structure measures obtained in magnetic resonance images of the distal radius and the calcaneus as well as computed tomographic images of the spine versus bone mineral density (BMD) of the spine and the calcaneus in the prediction of osteoporotic spine fracture status. MATERIAL AND METHODS: High-resolution magnetic resonance images of the calcaneus and the distal radius and thin-section computed tomographic images of thoracic and lumbar vertebrae were obtained from 74 cadavers. Structure analysis was performed using parameters analogous to standard histomorphometry. BMD of the spine was determined by using quantitative computed tomography and of the calcaneus by using dual x-ray absorptiometry. Spine radiographs of these cadavers were assessed concerning vertebral deformities. RESULTS: The diagnostic performance in differentiating fracture and nonfracture subjects was highest for structure parameters in the spine and slightly lower for these parameters in the distal radius and for BMD of the spine. CONCLUSION: In this study structure parameters in the spine were best suited to predict the osteoporotic fracture status of the spine.
Authors: E-M Lochmüller; K Pöschl; L Würstlin; M Matsuura; R Müller; T M Link; F Eckstein Journal: Osteoporos Int Date: 2007-10-03 Impact factor: 4.507
Authors: Arnold C Cheung; Miriam A Bredella; Ma'moun Al Khalaf; Michael Grasruck; Christianne Leidecker; Rajiv Gupta Journal: Skeletal Radiol Date: 2009-05-09 Impact factor: 2.199
Authors: Yusuf A Bhagat; Chamith S Rajapakse; Jeremy F Magland; Michael J Wald; Hee Kwon Song; Mary B Leonard; Felix W Wehrli Journal: Acad Radiol Date: 2011-08-04 Impact factor: 3.173
Authors: Thomas Baum; Melanie Kutscher; Dirk Müller; Christoph Räth; Felix Eckstein; Eva-Maria Lochmüller; Ernst J Rummeny; Thomas M Link; Jan S Bauer Journal: J Bone Miner Metab Date: 2012-11-22 Impact factor: 2.626
Authors: Glenn A Ladinsky; Branimir Vasilic; Andra M Popescu; Michael Wald; Babette S Zemel; Peter J Snyder; Louise Loh; Hee Kwon Song; Punam K Saha; Alexander C Wright; Felix W Wehrli Journal: J Bone Miner Res Date: 2008-01 Impact factor: 6.741